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The preoperative cholescintigrams of 16 patients with subacute or chronic gallbladder (GB) perforation demonstrated at surgery were reviewed, and the scintigraphic findings were characterized. Persistent GB nonvisualization was found in each study. Additional findings included a band of increased pericholecystic hepatic activity (PCHA) (n = 7) and/or a photopenic region in the GB fossa (n = 7). PCHA and photopenic region findings, when visualized, were most commonly associated with a subacute localized perforation with pericholecystic abscess formation. However, the sensitivity of each of these findings was only 44%. Cholescintigrams did not directly demonstrate the perforation site in any patient. Although the presence of the PCHA sign and/or GB fossa photopenic region appears to identify a subgroup of patients at increased risk for perforation, cholescintigraphy is relatively insensitive for detection of subacute or chronic GB perforation. 相似文献
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The stability of betamethasone-17-valerate in semi-solid bases has been investigated. Emphasis has been placed on the stability problems which could arise upon dilution of proprietary preparations by the use of model systems. Betamethasone-17-valerate has been shown to decompose to betamethasone-21-valerate and betamethasone alcohol. Quantitation of the decomposition was by direct densitometry on thin layer chromatographic plates. The decomposition was found to be an apparent first order process and to depend on the diluent used and its concentration. Attempts were also made to relate the rate of decomposition to the pH of the base used, and to stabilize the products. 相似文献
25.
Gallbladder nonvisualization in cholescintigraphy has been shown to be a reliable finding in acute cholecystitis. In some cholescintigrams, we have observed faintly increased pericholecystic hepatic activity in conjunction with gallbladder nonvisualization. To determine the frequency and significance of the pericholecystic hepatic activity finding, we evaluated 334 consecutive adult patients who had cholescintigrams with technetium-99m diisopropylphenylcarboamoyl iminodiacetic acid. Pericholecystic hepatic activity was seen in 21% of the abnormal scans demonstrating gallbladder nonvisualization but in none of the other scans. Thirteen of these patients underwent surgery; 11 (85%) were found to have acute cholecystitis, and two (15%) had chronic cholecystitis. Four patients (31%) had acute gangrenous cholecystitis, and five (39%) had cholecystitis complicated by gallbladder perforation. The pericholecystic hepatic activity sign is not specific for gangrenous cholecystitis or gallbladder perforation but does reliably indicate inflammatory gallbladder disease and is associated with a relatively high incidence of cholecystitis complicated by perforation. 相似文献
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Prognostic factors for the success rate of embryo freezing 总被引:5,自引:6,他引:5
Karlstrom PO; Bergh T; Forsberg AS; Sandkvist U; Wikland M 《Human reproduction (Oxford, England)》1997,12(6):1263-1266
To find some prognostic factors for the outcome of frozen-thawed cycles, we
have retrospectively analysed all frozen pre-embryos that were thawed
during 1993 and 1994 at two in-vitro fertilization (IVF) units in Sweden.
Supernumerary pre-embryos were frozen from 551 oocyte retrievals and these
resulted in 660 frozen-thawed cycles which lead to 623 thawed embryo
transfers. The outcome of these transfers was 137 clinical pregnancies with
a pregnancy rate of 22% per frozen-thawed embryo transfers. Women <40
years of age had a higher birth rate than those > or =40 years, 19 and
5% respectively (P < 0.01). Transfers with two and three pre-embryos
resulted in pregnancy rates of 23 and 27%, respectively, compared with 14%
for transfer of one embryo. A pregnancy resulting from the initial embryo
transfers had a predictive value for results of the subsequent
frozen-thawed cycle. Embryo grade and cleavage stage at the time of
freezing was important for the survival of the frozen-thawed pre-embryos.
The pregnancy rate was not influenced by the cleavage stage, but a tendency
toward a lower pregnancy rate was seen for the embryos with lower grading.
To conclude, cryopreservation seems to be beneficial in women <40 years
of age, who have supernumerary pre-embryos of good quality for freezing and
of which at least two can be transferred.
相似文献
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