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排序方式: 共有1241条查询结果,搜索用时 15 毫秒
991.
Stephen PJ Macdonald Yusuf Nagree Daniel M Fatovich Helen L Flavell Francis Loutsky 《Emergency medicine Australasia : EMA》2011,23(6):717-725
Objective: To compare two methods of risk stratification for suspected acute coronary syndrome (ACS) in the ED. Methods: A prospective observational multicentre study was undertaken of patients undergoing evaluation in the ED for possible ACS. We compared the National Heart Foundation of Australia/Cardiac Society of Australia and New Zealand (NHF/CSANZ) guideline and the Thrombolysis in Myocardial Infarction (TIMI) risk score for differentiating high‐ and low‐risk patients. Composite outcome was all cause death, myocardial infarction or coronary revascularisation within 30 days. Results: Of 1758 enrolments, 223 (13%) reached the study outcome. Area under the receiver operator characteristic (ROC) curve was 0.79 (95% CI 0.76–0.81) for the NHF/CSANZ group and 0.71 (0.68–0.75) for TIMI score based on initial troponin result (P < 0.001), and 0.82 (95% CI 0.80–0.84) and 0.76 (0.73–0.79) respectively when the 8–12 h troponin result is included (P = 0.001). Thirty day event rates were 33% for NHF/CSANZ high‐risk vs 1.5% for combined low/intermediate risk (P < 0.001). For TIMI score, 30 day event rates were 23% for a score ≥2 and 4.8% for TIMI < 2 (P < 0.001). The NHF/CSANZ guideline identified more patients as low risk compared with the TIMI risk score (61% vs 48%, P < 0.001). Conclusions: The NHF/CSANZ guideline is superior to the TIMI risk score for risk stratification of suspected ACS in the ED. 相似文献
992.
993.
New anticoagulants are being introduced into the market. These drugs are orally administered, have predictable pharmacokinetics and dose response, do not require monitoring and have an acceptable safety profile when used appropriately, and so avoid many of the disadvantages and possible complications of warfarin and heparin. Dabigatran is the most widely used, and has been approved by the Therapeutic Goods Administration. The use of dabigatran will likely increase in the coming years, and so it is important for dentists to be aware of its mechanism of action, the possible complications, and how to reverse the bleeding if it occurs. This review discusses dabigatran and reports on our experience of five cases, and provides practical clinical advice on how to manage patients on dabigatran who require dental treatment, particularly extractions. 相似文献
994.
Rachel L Sills Stephen PJ Macdonald Briony G Williams Jonathon D Burcham David McCutcheon Anne E Cordingley Daniel M Fatovich 《Emergency medicine Australasia : EMA》2020,32(3):515-517
Collaboration with consumers is an emerging focus for medical researchers worldwide. Public involvement is increasingly encouraged, and in some cases stipulated by funding bodies, in order to secure financial support. While consumer involvement could be viewed as another hurdle in the funding application process, it can add immense value to research outcomes. However, given the diverse and transient nature of our consumer group, how can we develop meaningful public engagement in emergency medicine research? 相似文献
995.
Gerben Keijzers Stephen PJ Macdonald Andrew A Udy Glenn Arendts Michael Bailey Rinaldo Bellomo Gabriel E Blecher Jonathon Burcham Andrew R Coggins Anthony Delaney Daniel M Fatovich John F Fraser Amanda Harley Peter Jones Frances B Kinnear Katya May Sandra Peake David McD Taylor Patricia Williams 《Emergency medicine Australasia : EMA》2020,32(4):586-598
996.
David van Bockel C. Mee Ling Munier Stuart Turville Steven G. Badman Gregory Walker Alberto Ospina Stella Anupriya Aggarwal Malinna Yeang Anna Condylios Anthony D. Kelleher Tanya L. Applegate Andrew Vallely David Whiley William Rawlinson Phillip Cunningham John Kaldor Rebecca Guy 《Viruses》2020,12(11)
997.
PJ Commerford 《Cardiovascular journal of Africa》2014,25(6):255-Dec;25(6):255
998.
Increased expression of the multidrug resistance-associated protein gene in relapsed acute leukemia 总被引:10,自引:2,他引:10
Schneider E; Cowan KH; Bader H; Toomey S; Schwartz GN; Karp JE; Burke PJ; Kaufmann SH 《Blood》1995,85(1):186-193
999.
1000.
PJ Commerford 《Cardiovascular journal of Africa》2015,26(6):203-Dec;26(6):203