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61.
Stavros I. Tyritzis Abolfazl Hosseini Justin Collins Tommy Nyberg Martin N. Jonsson Oscar Laurin Dinyar Khazaeli Christofer Adding Martin Schumacher N. Peter Wiklund 《European urology》2013
Background
Robot-assisted radical cystectomy (RARC) with totally intracorporeal neobladder diversion is a complex procedure that has been reported with good outcomes in small series.Objective
To present complications and oncologic and functional outcomes of this procedure.Design, setting, and participants
Between 2003 and 2012 in a tertiary referral center, 70 patients were operated on by two experienced robotic surgeons. Data were collected prospectively and reviewed retrospectively.Intervention
RARC with totally intracorporeal modified Studer ileal neobladder formation.Outcome measurements and statistical analysis
The overall outcome of RARC with a totally intracorporeal neobladder was presented by assessing (1) surgical margins, (2) recurrence or cancer-specific death at 24 mo, (3) 30-d and 90-d complications graded according to the modified Clavien-Dindo system, (4) daytime and nighttime continence (no or one pad per day) at 6 and 12 mo, and (5) satisfactory sexual activity or potency at 6 mo and 12 mo. Survival rates were estimated by Kaplan-Meier plots.Results and limitations
Median follow-up of the cohort was 30.3 mo (interquartile range: 12.7–35.6). We recorded negative margins in 69 of 70 patients (98.6%). Clavien 3–5 complications occurred in 22 of 70 patients (31.4%) at 30 d and 13 of 70 (18.6%) at >30 d. At 90 d, the overall complication rate was 58.5%. Clavien <3 and Clavien ≥3 complications were recorded in 15 of 70 patients (21.4%) and 26 of 70 (37.1%), respectively. Kaplan-Meier estimates for recurrence-free, cancer-specific, and overall survival at 24 mo were 80.7%, 88.9%, and 88.9%, respectively. Daytime continence and satisfactory sexual function or potency at 12 mo ranged between 70% and 90% in both men and women. Limitations of this study include its retrospective design, selection bias due to the learning curve phase, and missing data.Conclusions
In this expert center for RARC, outcomes after RARC with totally intracorporeal neobladder diversion appear satisfactory and in line with contemporary open series. 相似文献62.
Lisa Lieberman Una Diffley Sandy King Shelley Chanler Maryanne Ferrara Oscar Alleyne Joan Facelle 《American journal of public health》2013,103(11):1942-1948
In 2000, Rockland County, a small suburban county north of New York City, dedicated $1 million of its Master Settlement Agreement funds to a comprehensive tobacco control program, Put It Out Rockland. Developed and implemented by the county health department, this program used an essential public health services model and an ongoing financial investment, within the context of strong statewide tobacco control efforts, to lower adult smoking rates to 9.7% and to reduce both smoking among youths and exposure to secondhand smoke over the ensuing decade. By combining state funds and local dollars for a total of $6.75 cost per capita, this comprehensive effort yielded 11 000 fewer smokers and translated to a potential savings of more than $24 million for the county. 相似文献
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Population genomic and genome-wide association studies of agroclimatic traits in sorghum 总被引:5,自引:0,他引:5
Geoffrey P. Morris Punna Ramu Santosh P. Deshpande C. Thomas Hash Trushar Shah Hari D. Upadhyaya Oscar Riera-Lizarazu Patrick J. Brown Charlotte B. Acharya Sharon E. Mitchell James Harriman Jeffrey C. Glaubitz Edward S. Buckler Stephen Kresovich 《Proceedings of the National Academy of Sciences of the United States of America》2013,110(2):453-458
66.
Meghan D. Althoff Colin Anderson-Smits Stephanie Kovacs Oscar Salinas John Hembling Norine Schmidt Patricia Kissinger 《AIDS and behavior》2013,17(7):2416-2425
Multiple sexual partnerships (MSP), both concurrent and serial short gap, are thought to increase the risk of HIV and sexually transmitted infection (STI) acquisition and transmission. In this study we evaluate potential individual and environmental risk factors for engaging in MSP in a cohort of newly arrived Latino migrant men (LMM) in New Orleans, LA, USA. Participants were surveyed at three time points over a nine-month period to examine factors associated with MSP. Of the 113 men, 32.5 % reported ever MSP. In 290 observations, 19.5 % of men had concurrent, and 15.0 % had serial short gap partnerships in at least one interviews. Substance was associated with MSP, OR (95 % CI) 2.00 (1.16, 3.45) whereas belonging to a community organization was found to be protective, OR 0.32 (0.17, 0.59). Interventions to reduce substance use and promote social connection are needed to prevent a potential HIV/STI epidemic in this population. 相似文献
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