全文获取类型
收费全文 | 144篇 |
免费 | 4篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 4篇 |
妇产科学 | 6篇 |
基础医学 | 11篇 |
临床医学 | 14篇 |
内科学 | 22篇 |
皮肤病学 | 3篇 |
神经病学 | 8篇 |
特种医学 | 6篇 |
外科学 | 22篇 |
综合类 | 2篇 |
预防医学 | 5篇 |
眼科学 | 38篇 |
药学 | 6篇 |
出版年
2022年 | 1篇 |
2021年 | 6篇 |
2020年 | 2篇 |
2019年 | 2篇 |
2018年 | 7篇 |
2017年 | 2篇 |
2016年 | 4篇 |
2015年 | 3篇 |
2014年 | 7篇 |
2013年 | 5篇 |
2012年 | 15篇 |
2011年 | 15篇 |
2010年 | 12篇 |
2009年 | 3篇 |
2008年 | 15篇 |
2007年 | 6篇 |
2006年 | 9篇 |
2005年 | 8篇 |
2004年 | 11篇 |
2003年 | 5篇 |
2002年 | 7篇 |
2001年 | 1篇 |
1997年 | 1篇 |
1992年 | 1篇 |
排序方式: 共有148条查询结果,搜索用时 15 毫秒
141.
Rationale, aims and objectives This study aimed to develop a scale that can be used to assess the perceptions of the community about physicians and their medical practice. Methods A Likert‐type scale was developed and applied to 220 subjects twice within a 7–10 day interval. Internal consistency reliability and test–retest reliability were used as indicators of the reliability of the scale. Results Chronbach’s alpha values obtained from two reliability tests were 0.82 and 0.83, respectively, and correlation coefficient between the two tests was 0.61. The mean value of items indicated that perceptions about physicians were between ‘negative’ and ‘neutral’. Conclusions The reliability of this scale was found to be at acceptable levels and therefore it can be used to assess the perceptions of people from different social classes about physicians. 相似文献
142.
Soysal A Atay T Ozu T Arpaci B 《The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques》2004,31(3):357-362
OBJECTIVE: Motor and sensory nerve conductions, F responses, sympathetic skin responses and R-R interval variations (RRIV) were studied to determine the type of peripheral neuropathy among patients with leprosy. METHODS: Twenty-nine consecutive patients with leprosy (25 male, 4 female) hospitalized in the "Istanbul Leprosy Hospital" between January - December, 1999 were included in this study. Ten patients had borderline lepromatous leprosy, and 19 had lepromatous leprosy. None of the patients studied had the tuberculoid form. The mean age was 55 +/- 12 years. The control group consisted of 30 (26 male, 4 female) healthy volunteers (mean age: 58.1 +/- 7.8 years). All subjects included in the study underwent neurological examination and electrophysiological evaluation. Standard procedures were performed for evaluating sensory and motor conduction studies. Motor studies were carried out on both left and right median, ulnar, tibial and common peroneal nerves while median, ulnar, sural and superficial peroneal nerves were examined for sensory studies. Sympathetic skin response recordings on both hands and RRIV recordings on precordial region were done in order to evaluate the autonomic involvement. RESULTS: The lower extremity was found to be more severely affected than the upper, and sensory impairment predominated over motor. Of 58 upper limbs examined, no sympathetic skin responses was recorded in 46 (79.3%). Compared with the controls, the RRIVs of the leprosy patients were found to be reduced during both resting and deep forced hyperventilation. CONCLUSION: Our results indicate that leprosy causes a predominantly axonal polyneuropathy that is more severe in the lower extremities. Sensory nerve damage is accompanied by autonomic involvement. 相似文献
143.
Corneal topographic changes after retinal detachment surgery 总被引:1,自引:0,他引:1
PURPOSE: To evaluate the changes in corneal topography after scleral buckling surgery for retinal detachment. METHODS: Twenty-one eyes of 21 patients with the diagnosis of retinal detachment were included in this prospective study. Scleral buckling surgery was performed on all patients. The corneal topography of each was measured before surgery and at 1 week and 1 and 6 months after surgery by computer-assisted videokeratoscopy using the EyeSys 2000 Corneal Analysis System. Changes in corneal videokeratographies were analyzed using the Holladay Diagnostic Summary (HDS) software package. RESULTS: A statistically significant central corneal steepening (average, 1.8 diopter) was noted 1 week after surgery. The total and irregular astigmatic components both revealed a significant but transient increase in the first postoperative month. All these topographic changes persisted for as long as 6 months but returned to preoperative values afterward. CONCLUSION: Scleral buckling was found to induce transient changes in corneal topography producing both myopia and corneal astigmatism. Videokeratography is helpful for documenting such corneal changes after scleral buckling surgery for retinal detachment. 相似文献
144.
A study on the toxicity of intravitreal levofloxacin in rabbits 总被引:4,自引:0,他引:4
PURPOSE: To investigate the retinal toxicity of different doses of intravitreal injections of levofloxacin in a rabbit model, which is the levorotatory component of ofloxacin and approximately twice as potent as ofloxacin and highly active in vitro against gram-positive and -negative bacteria, and anaerobic bacteria including many ocular pathogens. METHODS: Sixteen albino rabbits were used in this study, and divided four groups. Levofloxacin in doses of 50, 100, 250 and 500 microg was injected into the midvitreous of rabbit's left eyes. The other eye served as a control and received normal saline solution. Indirect ophthalmoscopy, electroretinography (ERG) and light microscopy were used for retinal toxicity of levofloxacin. ERGs were recorded before injection and at 1(st) day, 1(st), 2(nd) and 4(th) weeks. At the end of follow-up period, the rabbits were killed and the eyes were enucleated for histologic evaluation. RESULTS: Intravitreal injections of 50, 100, 250 and 500 microg levofloxacin did not cause any deterioration of the a-wave, b-wave or oscillatory potentials of ERG throughout the follow-up period of 4 weeks. No evidence of retinal toxicity was observed by indirect ophthalmoscopy and light microscopy in any case. CONCLUSIONS: In therapeutic doses of 500 microg or less, intravitreal levofloxacin does not have retinal toxicity in rabbit eyes and this dose was well above the MIC(90) values of ocular pathogens that cause endophthalmitis. If future studies in other species confirm our findings, intravitreal levofloxacin may be a potentially important drug in the treatment and prevention of clinical bacterial endophthalmitis. 相似文献
145.
146.
Clinical factors affecting the direct cost of patients hospitalized with acute exacerbation of chronic obstructive pulmonary disease 总被引:2,自引:0,他引:2
Ornek T Tor M Altın R Atalay F Geredeli E Soylu O Erboy F 《International journal of medical sciences》2012,9(4):285-290
Background: Chronic obstructive pulmonary disease (COPD) is a disease of increasing significance in terms of economic and social burden due to its increasing prevalence and high costs. Direct costs of COPD are mostly associated with hospitalization expenditures. In this study, our objective was to investigate the costs of hospitalization and factors affecting these costs in patients hospitalized due to acute exacerbation of COPD (AECOPD).Methods: A total of 284 patients hospitalized AECOPD were included in the study. Data were examined retrospectively using the electronic hospital charts.Results: Mean duration of hospitalization was 11.38 ± 6.94 days among study patients. Rates of admission to the intensive care unit, initiation of non-invasive mechanical ventilation (NIMV) and invasive mechanical ventilation (MIV) were 37.3% (n=106), 44.4% (n=126) and 18.3% (n=52) respectively. The rate of mortality was 14.8% (n=42). Mean cost of a single patient hospitalized for an AECOPD was calculated as $1765 ± 2139. Mean cost of admission was $889 ± 533 in standard ward, and $2508 ± 2857 in intensive care unit (ICU). The duration of hospitalization, a FEV1% predicted value below 30%, having smoked 40 package-years or more, the number of co-morbidities, NIMV, IMV, ICU, exitus and the number of hospitalizations in the past year were among the factors that increased costs significantly. Hospital acquired pneumonia, chronic renal failure and anemia also increased the costs of COPD significantly.Conclusion: The costs of treatment increase with the severity of COPD or with progression to a higher stage. Efforts and expenditures aimed at preventing COPD exacerbations might decrease the costs in COPD. 相似文献
147.
Cagatay Ozturk Selhan Karadereler Ibrahim Ornek Meric Enercan Kursat Ganiyusufoglu Azmi Hamzaoglu 《International orthopaedics》2010,34(4):543-546
The routine use of magnetic resonance imaging (MRI) in adolescent idiopathic scoliosis remains controversial, and current
indications for MRI in idiopathic scoliosis vary from study to study. The purpose of this study was to demonstrate the prevalence
of neural axis malformations and the clinical relevance of routine MRI studies in the evaluation of patients with adolescent
idiopathic scoliosis undergoing surgical intervention without any neurological findings. A total of 249 patients with a diagnosis
of idiopathic scoliosis were treated surgically between the years 2002 and 2007. A routine whole spine MRI analysis was performed
in all patients. On the preoperative clinical examination, all patients were neurologically intact. There were 20 (8%) patients
(3 males and 17 females) who had neural axis abnormalities on MRI. Three of those 20 patients needed additional neurosurgical
procedures before corrective surgery; the remaining underwent corrective spinal surgery without any neurosurgical operations.
Magnetic resonance imaging may be beneficial for patients with presumed idiopathic scoliosis even in the absence of neurological
findings and it is ideally performed from the level of the brainstem to the sacrum. 相似文献
148.
Arslan M Cantürk M Ornek D Gamli M Pala Y Dikmen B Basaran M 《Clinics (S?o Paulo, Brazil)》2010,65(9):831-835