全文获取类型
收费全文 | 296056篇 |
免费 | 17219篇 |
国内免费 | 414篇 |
专业分类
耳鼻咽喉 | 4205篇 |
儿科学 | 10283篇 |
妇产科学 | 10243篇 |
基础医学 | 44943篇 |
口腔科学 | 7496篇 |
临床医学 | 24146篇 |
内科学 | 55747篇 |
皮肤病学 | 6309篇 |
神经病学 | 20992篇 |
特种医学 | 11610篇 |
外国民族医学 | 43篇 |
外科学 | 46650篇 |
综合类 | 7765篇 |
现状与发展 | 1篇 |
一般理论 | 160篇 |
预防医学 | 19893篇 |
眼科学 | 6943篇 |
药学 | 20865篇 |
中国医学 | 787篇 |
肿瘤学 | 14608篇 |
出版年
2018年 | 3611篇 |
2017年 | 2650篇 |
2016年 | 3069篇 |
2015年 | 3486篇 |
2014年 | 4569篇 |
2013年 | 7198篇 |
2012年 | 9050篇 |
2011年 | 9435篇 |
2010年 | 6119篇 |
2009年 | 5541篇 |
2008年 | 8659篇 |
2007年 | 9507篇 |
2006年 | 9348篇 |
2005年 | 8944篇 |
2004年 | 8654篇 |
2003年 | 8157篇 |
2002年 | 7753篇 |
2001年 | 13318篇 |
2000年 | 13646篇 |
1999年 | 11415篇 |
1998年 | 3022篇 |
1997年 | 2788篇 |
1996年 | 2633篇 |
1995年 | 2544篇 |
1994年 | 2342篇 |
1992年 | 8312篇 |
1991年 | 8449篇 |
1990年 | 8259篇 |
1989年 | 8075篇 |
1988年 | 7313篇 |
1987年 | 7071篇 |
1986年 | 6719篇 |
1985年 | 6514篇 |
1984年 | 4760篇 |
1983年 | 4118篇 |
1982年 | 2469篇 |
1979年 | 4427篇 |
1978年 | 3228篇 |
1977年 | 2731篇 |
1976年 | 2503篇 |
1975年 | 2833篇 |
1974年 | 3352篇 |
1973年 | 3362篇 |
1972年 | 3118篇 |
1971年 | 2948篇 |
1970年 | 2838篇 |
1969年 | 2581篇 |
1968年 | 2538篇 |
1967年 | 2373篇 |
1966年 | 2264篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
141.
142.
J L Dubois-Randé D Loisance A M Duval-Moulin P Deleuze D Lellouche O Tavolaro L Hittinger C Benvenuti P Merlet D Brun 《Archives des maladies du coeur et des vaisseaux》1989,82(8):1433-1438
Enoximone is a positive inotropic agent belonging to the group of phosphodiesterase F-III inhibitors. The drug was tested in 34 patients uncontrolled by sympathomimetic drugs and referred to our department for urgent heart transplantation or circulatory assistance. After insertion of a Swan-Ganzgatheter and a radial artery catheter for haemodynamic monitoring, enoximone was administered as a 15-minute intravenous bolus injection of 1 to 2.5 mg/kf every 8 hours, in addition to sympathomimetic agents. Clinical and haemodynamic improvement was observed after thirty minutes in 30 patients. The cardiac index rose from 1.82 to 2.67 l/min/m2 and the pulmonary wedge pressure fell from 30.8 to 18.9 mmHg. Systemic arterial resistance decreased from 2170 to 1520 dyn. s. cm-5, and pulmonary resistance from 5.5 to 4.6 Wood units (p less than 0.01 for all values). Four patients had no haemodynamic improvement and were put on circulatory assistance, using a Jarvik 7 total artificial heart in 3 of them and heterotopic circulatory assistance in one. After clinical investigation for contra-indication to heart transplantation, and as their improved haemodynamic status permitted, 12 of the 30 patients were considered suitable (group B) for heart transplantation. Transplantation was performed within a week of admission in 11 patients without any need for mechanical assistance. One of the group B patients who required implantation of a Jarvik 7 artificial heart died after 12 hours of assistance. Eighteen patients were considered unsuitable for transplantation (group A) and treated medically.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
143.
144.
V. E. Kataev O. I. Militsina I. Yu. Strobykina G. I. Kovylyaeva R. Z. Musin O. V. Fedorova G. L. Rusinov M. N. Zueva G. G. Mordovskoi A. G. Tolstikov 《Pharmaceutical Chemistry Journal》2006,40(9):473-475
Diesters based on isosteviol and dicarboxylic acids were synthesized and tested for antituberculous activity. Isosteviol and
some of its derivatives exhibit appreciable tuberculostatic properties in vitro, the activity being dependent on the length of the polymethylene spacer connecting two ent-beyeran fragments. The mechanism of the antituberculous action of isosteviol derivatives are discussed.
__________
Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 40, No. 9, pp. 12–13, September, 2006. 相似文献
145.
F. Cotton O. Pellet F.-N. Gilly A. Granier L. Sournac O. Glehen 《European journal of surgical oncology》2006,32(10):1212-1216
AIM: Peritonectomy procedures with intraperitoneal chemohyperthermia are an effective but costly treatment for peritoneal carcinomatosis (PC). Consequently a proper selection of patients is necessary. We evaluated the benefit of MRI prior to surgery, in the detection of two of the main surgery contraindications: bulky mesenteric tumors and bladder implants. METHODS: Three experts retrospectively reviewed abdominal and pelvic MRI from 19 cases of surgically proved PC (ovary: 7; colorectal: 7; gastric: 2; pseudomyxoma peritonei: 2; appendix: 1). RESULTS: Mesenteric tumors were always identified as hypersignal masses on axial and coronal fat suppression gadolinium-enhanced T1 images (n=3). Three out of five bladder implants were detected. The two cases of bladder implants that were not detected on MRI were missed because the bladder was not filled. The best sequence for the detection of bladder involvement was axial T2-weighted images with bladder filling. CONCLUSIONS: Evaluating the preoperative resectability of PC is crucial for patient management. MRI seems to reliably detect bulky mesenteric tumors and bladder implants on condition the bladder is filled and appropriate sequences are used. 相似文献
146.
TB in the elderly in industrialised countries. 总被引:1,自引:0,他引:1
Peter D O Davies 《The international journal of tuberculosis and lung disease》2007,11(11):1157-1159
147.
J. de Rotrou L. Battal-Merlet E. Wenisch C. Chausson E. Bizet F. Dray H. Lenoir A.-S. Rigaud O. Hanon 《European journal of neurology》2007,14(2):144-149
Within the context of early diagnosis of Alzheimer's disease (AD), there is a growing interest in neuropsychological screening tests. Amongst these tests, we focused on the largely used Memory Impairment Screen (MIS). The objective of the present work was to show that adding a 10-min delayed recall to the MIS, improves the test psychometric characteristics in order to detect dementia in the earliest stages. A prospective study was carried out on a cohort of 270 consecutive elderly ambulatory subjects attending the Broca Hospital Memory Clinic: normal controls ( n = 67), mild cognitive impairment subjects ( n = 98) and mildly demented patients [ n = 105, Mini Mental State Examination (MMSE) = 23 ± 4]. This study consisted in testing the advantage of the 10-min delayed recall entitled MIS-D compared with the MIS. At a cut-off score of 6, the MIS-D revealed satisfying psychometric characteristics with a sensitivity of 81% and a specificity of 91%, whilst the MIS alone indicated a sensitivity of 60% and a specificity of 88% in detecting dementia. In demented patients with MMSE score ≥26, MIS-D properties still remained satisfying (sensitivity: 75%, specificity: 92%). MIS-D is a more relevant screening test than MIS alone at very early stages of dementia. 相似文献
148.
T S Gur'eva O A Dadasheva V V Tsetlin E I Mednikova Z N Lebedeva 《Aviakosmicheskaia i ekologicheskaia meditsina》2007,41(1):20-24
Experiments on Japanese quail embryogenesis on a background of chronic exposure to gamma- and neutron doses comparable with the doses of ionized radiation inside the orbital space stations Mir and ISS, and exploration vehicles gave evidence that permanent absorption of low gamma-doses (0,15 cgy/d) did not impact development of the Japanese quail embryos. On the contrary, the neutron dose of 200 microgy/d imparted by the neutron flux of 30 particles/cm2s was hazardous to embryos as it caused morphological disorders in 12% of embryos. 相似文献
149.
Irina O Pohodenko-Chudakova 《Journal of cranio-maxillo-facial surgery》2005,33(2):118-122
BACKGROUND: The present study investigated the use of acupuncture analgesia in maxillofacial surgery. PATIENTS AND METHODS: Acupuncture analgesia was applied in 120 patients. In 20 of these, surgery was carried out under general anaesthesia in combination with acupuncture analgesia. In 100 patients, acupuncture analgesia was applied in addition to traditional postoperative analgesia. In case of troublesome postoperative pain, it was necessary to carry out additional sessions (1-4) of acupuncture stimulation. RESULTS: When acupuncture analgesia was used, the pulse rate and blood pressure during surgery generally remained stable. In the present study serum cortisol was also measured and showed only minor elevation. DISCUSSION: The present study demonstrated favourable results when the first variant of the brake method of acupoint stimulation was used for 40-50 min with additional manual twirling of the needles. This involved inserting needles into the acupoints and, using slow, rolling manual movements increasing the amplitude step-by-step provoking simultaneous especially strong patient sensations. CONCLUSION: Acupuncture analgesia can be a useful adjunct to conventional anaesthesia in maxillofacial surgery. 相似文献
150.
Keratography as a guide to selective suture removal for the reduction of astigmatism after penetrating keratoplasty 总被引:2,自引:0,他引:2
After penetrating keratoplasty in 52 eyes, keratography refraction and keratometry were used to select appropriate interrupted sutures for removal in order to reduce astigmatism. All eyes had one continuous and either 12 or 16 interrupted nylon sutures. The keratographs were examined retrospectively and separated into six groups on the basis of similar mire patterns. The removal of single sutures associated with three of these patterns reduced astigmatism by the following average amounts: symmetrical oval pattern, 0.44 diopters (D); D-shaped oval pattern, 2.07 D; and focal indentation pattern, 6.60 D. The other three patterns--mildly disrupted mires, incomplete mires, and uninterpretable mires--did not allow quantification of results. Examples of these keratographic patterns are presented and recommendations are made for their use in the management of astigmatism following penetrating keratoplasty. 相似文献