全文获取类型
收费全文 | 23150篇 |
免费 | 1167篇 |
国内免费 | 88篇 |
专业分类
耳鼻咽喉 | 138篇 |
儿科学 | 349篇 |
妇产科学 | 374篇 |
基础医学 | 2900篇 |
口腔科学 | 749篇 |
临床医学 | 1676篇 |
内科学 | 5532篇 |
皮肤病学 | 426篇 |
神经病学 | 2135篇 |
特种医学 | 1034篇 |
外科学 | 3531篇 |
综合类 | 93篇 |
预防医学 | 661篇 |
眼科学 | 425篇 |
药学 | 1859篇 |
中国医学 | 56篇 |
肿瘤学 | 2467篇 |
出版年
2023年 | 115篇 |
2022年 | 216篇 |
2021年 | 382篇 |
2020年 | 223篇 |
2019年 | 321篇 |
2018年 | 372篇 |
2017年 | 289篇 |
2016年 | 370篇 |
2015年 | 386篇 |
2014年 | 529篇 |
2013年 | 626篇 |
2012年 | 975篇 |
2011年 | 1126篇 |
2010年 | 572篇 |
2009年 | 532篇 |
2008年 | 987篇 |
2007年 | 1007篇 |
2006年 | 965篇 |
2005年 | 969篇 |
2004年 | 957篇 |
2003年 | 933篇 |
2002年 | 960篇 |
2001年 | 921篇 |
2000年 | 942篇 |
1999年 | 918篇 |
1998年 | 293篇 |
1997年 | 237篇 |
1996年 | 221篇 |
1995年 | 186篇 |
1994年 | 166篇 |
1993年 | 150篇 |
1992年 | 652篇 |
1991年 | 565篇 |
1990年 | 597篇 |
1989年 | 578篇 |
1988年 | 493篇 |
1987年 | 456篇 |
1986年 | 451篇 |
1985年 | 403篇 |
1984年 | 278篇 |
1983年 | 235篇 |
1980年 | 91篇 |
1979年 | 240篇 |
1978年 | 142篇 |
1977年 | 128篇 |
1975年 | 100篇 |
1974年 | 95篇 |
1972年 | 105篇 |
1971年 | 103篇 |
1969年 | 101篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
Hirofumi Tomiyama Jiko Yamada Yutaka Koji Minoru Yambe Kohki Motobe Kazuki Shiina Yoshio Yamamoto Akira Yamashina 《Hypertension research》2007,30(5):417-426
This observational study of Japanese men without metabolic syndrome (MetS) (age: 41+/-8 years) was conducted to clarify whether or not heart rate elevation precedes the development of full-blown MetS. MetS was defined based on two modifications of the criteria of the Japanese Expert Committee on the Diagnosis and Classification of Metabolic Syndrome. Premetabolic syndrome subjects were defined as those having one component of MetS with increased body mass index (BMI). Among the subjects without MetS (n=1,859 when the BMI criterion was >or=25 and n=2,020 when the BMI criterion was >or=27.5), the incidence of progression to full-blown MetS by the time of the second examination at the end of the 3-year study period was higher in the subjects with premetabolic syndrome than in those without it. The receiver-operator characteristic curve analysis and binary logistic regression analysis revealed that the odds ratio (OR) of a heart rate >or=69 beats/min at the first examination for progression to full-blown MetS by the time of the second examination was significant in subjects with premetabolic syndrome (BMI>or=25: OR=3.64 [1.22-10.88]; BMI>or=27.5: OR=3.67 [1.28-10.55]; p<0.05). Thus, heart rate elevation appears to precede the development of full-blown MetS in subjects with premetabolic syndrome. Heart rate seems to be a simple and useful marker for predicting the progression to full-blown MetS of middle-aged Japanese men with premetabolic syndrome. 相似文献
22.
Soichiro Yoshida Tetsuo Hayashi Makoto Morozumi Hisato Osada Norinari Honda Takumi Yamada 《International journal of urology》2007,14(7):665-667
The incidence of stonestreet formation after extracorporeal shock wave lithotripsy (ESWL) rises with increasing stone burden. However, stonestreet after ESWL is often experienced even in stones smaller than 20 mm. To examine whether the non-contrast helical computed tomography (CT) data could predict stonestreet formation in these stones, 53 radiopaque stones of 5-20 mm treated with ESWL were evaluated. Maximal dimension was measured on plain radiograph. From an attenuation value histogram graphed from the CT data, total stone volume and mean attenuation value were calculated. Seven stonestreets longer than 25 mm developed. There was no significant difference in maximal dimension and total stone volume between stones that did and stones that did not develop stonestreet. Mean attenuation value was the sole significant predictive factor. Application of mean attenuation value with cut-off level of 650 HU would anticipate stonestreet formation with a sensitivity of 85.7% and a specificity of 71.7%. The estimated risk of stonestreet formation is high in the treatment of stones with higher mean attenuation value. 相似文献
23.
Seiichi Saito Shunichi Namiki Kenji Numahata Makoto Satoh Shigeto Ishidoya Akihiro Ito Haruo Nakagawa Yasuhiro Kaiho Takehiko Sanada Atsushi Yamada Yoichi Arai 《International journal of urology》2007,14(2):133-139
PURPOSE: To determine the effect of an interposition nerve graft on sexual function after radical prostatectomy. METHODS: This study includes 64 patients, without hormonal therapy, who underwent a radical prostatectomy and intraoperative electrophysiological confirmation of cavernous nerve preservation. Twelve patients underwent a unilateral interposition sural nerve graft (UNG) for the resected neurovascular bundle. Twenty-one and 31 patients underwent bilateral nerve-sparing (BNS) and unilateral nerve-sparing (UNS) surgery without a nerve graft, respectively. As the age of patients was significantly younger in the UNG group than in the other groups, age-matched analysis also was conducted. Sexual function, evaluated by a self-administered questionnaire using the University of California Los Angeles-Prostate Cancer Index, was compared statistically among the three groups. RESULTS: In the age-matched analysis, the postoperative sexual function (SXF) score of the UNG group showed an intermediate level of recovery between those of the BNS and UNS groups at 12 months and reached the same level as the score at 12 months of the BNS group at 18 months postoperatively. The difference in the SXF score between the UNG and UNS groups began to appear after 6 months postoperatively and increased steadily with time. However, the background factors, such as the baseline SXF score, the usage rate of phosphodiesterase 5 inhibitors, and the rate of comorbidities were different between the UNG and UNS groups. CONCLUSIONS: The difference of the SXF score between the UNG and UNS groups increased with time after 6 months postoperatively. However, it might be difficult at present to attribute a better recovery of the SXF score to the nerve graft because of the difference in the background factors between the groups. 相似文献
24.
Taizen Nakase Toshiki Mizuno Sanae Harada Kei Yamada Tsunehiko Nishimura Kotaro Ozasa Yoshiyuki Watanabe Ken Nagata 《Journal of clinical neuroscience》2007,14(10):943-947
While gene polymorphism for angiotensinogen (AGT) is reported to contribute to the regulation of blood pressure and salt sensitivity, its effect on the risk of ischemic stroke remains controversial. We hypothesized that polymorphism of the AGT gene could be a risk factor for ischemic stroke. Major clinical risk factors and the AGT gene M235T polymorphism were examined in 147 consecutive stroke patients and 133 healthy age-matched controls. All patients were categorized into four stroke types (single lacuna, multiple lacunae, large-artery atherosclerosis and branch atheromatous disease in brainstem) and two vascular groups (large and perforating arterial lesions). The AGT gene M allele significantly increased the risk of single lacuna, multiple lacunae and small arterial lesions, in male patients (p=0.029, 0.031 and 0.026, respectively). Synergistic effects of the AGT gene polymorphism and clinical risks were not observed. In conclusion, AGT M allele may present a risk of lacunar infarctions in Japanese men, independent of hypertension. 相似文献
25.
Kazumichi Yamada Satoshi Goto Taro Oyama Makoto Yoshikawa Shinji Nagahiro Yukitaka Ushio 《Acta neuropathologica》1995,89(2):172-177
The present study concerns the vulnerability of striatal interneurons immunopositive for the Ca2+-binding protein calretinin to ischemic neuronal injury. An immunohistochemical study was carried out on the striata of rats which had undergone transient middle cerebral artery occlusion. Two weeks after the ischemia, there was a marked reduction in the number of calretinin-positive neurons in the ipsilateral ischemic lesion, although the striatal interneurons positive for parvalbumin, which are a neuronal population distinct from the calretinin-immunoreactive cells in the striatum, were spared in the insulted areas. The present data indicate that the striatal calretinin-positive neurons are less resistant to transient ischemia, suggesting that there may exist vulnerability differences among the striatal interneurons in ischemia-induced neuronal injury. 相似文献
26.
Staging of esophageal carcinoma in vitro with 4.7-T MR imaging 总被引:4,自引:0,他引:4
27.
Kozo Yamada Seiji Hayasaka Yukari Yamamoto Tomoichi Setogawa 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》1990,228(1):1-4
We examined 62 patients with acute herpes zoster involving the trigeminal nerve; 13 had eruptions only and 49 (51 eyes) had
eruptions with ocular complications. Bilateral involvement was found in two patients. The frequency of the disease appeared
to increase with age, and the disease was least active in November. Patients with eruptions only demonstrated affected areas
along the first, second, and/or third divisions of the trigeminal nerve. Ocular complications occurred in patients who had
eruptions along the first and/or second divisions of the nerve, and they were usually noted in patients with eruptions on
the tip and one side of the node. The ocular complications and associated systemic conditions varied. 相似文献
28.
29.
30.