全文获取类型
收费全文 | 12935篇 |
免费 | 705篇 |
国内免费 | 47篇 |
专业分类
耳鼻咽喉 | 188篇 |
儿科学 | 381篇 |
妇产科学 | 208篇 |
基础医学 | 1744篇 |
口腔科学 | 416篇 |
临床医学 | 857篇 |
内科学 | 3054篇 |
皮肤病学 | 236篇 |
神经病学 | 888篇 |
特种医学 | 560篇 |
外科学 | 2372篇 |
综合类 | 58篇 |
一般理论 | 1篇 |
预防医学 | 285篇 |
眼科学 | 153篇 |
药学 | 819篇 |
中国医学 | 43篇 |
肿瘤学 | 1424篇 |
出版年
2023年 | 55篇 |
2022年 | 116篇 |
2021年 | 256篇 |
2020年 | 144篇 |
2019年 | 193篇 |
2018年 | 269篇 |
2017年 | 218篇 |
2016年 | 277篇 |
2015年 | 264篇 |
2014年 | 340篇 |
2013年 | 425篇 |
2012年 | 592篇 |
2011年 | 640篇 |
2010年 | 357篇 |
2009年 | 310篇 |
2008年 | 534篇 |
2007年 | 597篇 |
2006年 | 623篇 |
2005年 | 627篇 |
2004年 | 616篇 |
2003年 | 588篇 |
2002年 | 635篇 |
2001年 | 454篇 |
2000年 | 457篇 |
1999年 | 377篇 |
1998年 | 185篇 |
1997年 | 136篇 |
1996年 | 132篇 |
1995年 | 124篇 |
1994年 | 104篇 |
1993年 | 92篇 |
1992年 | 344篇 |
1991年 | 284篇 |
1990年 | 255篇 |
1989年 | 277篇 |
1988年 | 230篇 |
1987年 | 196篇 |
1986年 | 177篇 |
1985年 | 203篇 |
1984年 | 154篇 |
1983年 | 96篇 |
1979年 | 69篇 |
1977年 | 49篇 |
1974年 | 51篇 |
1973年 | 49篇 |
1971年 | 46篇 |
1970年 | 41篇 |
1969年 | 49篇 |
1968年 | 46篇 |
1966年 | 39篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
11.
Fengshi Chen Toru Bando Nobuharu Hanaoka Tatsuo Fukuse Seiki Hasegawa Hiromi Wada 《The Japanese Journal of Thoracic and Cardiovascular Surgery》2005,53(10):562-564
Ganciclovir resistance in cytomegalovirus (CMV) is an increasing problem in lung-transplant recipients with adverse clinical outcomes. We experienced the successful treatment of ganciclovir-resistant CMV infection in a lung-transplant recipient still receiving CMV prophylaxis. A 24-year-old woman with lymphangioleiomyomatosis underwent a living-donor lobar lung transplantation. She was a primary CMV mismatch (D+/R-) patient. She recovered from her postoperative complications, and was about to be discharged. However, she suffered ganciclovir-resistant CMV infection during prophylactic therapy. She was successfully treated with foscarnet, and is now alive without recurrence 18 months after surgery. 相似文献
12.
13.
Koh-ichi Sakata Masanori Someya Mutsuko Omatsu Hiroko Asanuma Tadashi Hasegawa Masato Hareyama Tetsuo Himi 《BMC cancer》2007,7(1):229
Background
Nasal NK/T cell lymphoma is an aggressive disease and has a poor prognosis. Nasal NK/T cell lymphoma is refractory to conventional chemotherapy and has strong tendency of widespread relapse or dissemination into distant sites. 相似文献14.
K. Arima Minako Nakamura Nobuhiko Sunohara Masafumi Ogawa Midori Anno Yoko Izumiyama Shigeo Hirai Kazuhiko Ikeda 《Acta neuropathologica》1997,93(6):558-566
Coiled bodies and interfascicular threads are conspicuous white matter abnormalities of brains of patients with progressive
supranuclear palsy (PSP). Both structures are argyrophilic and immunoreactive for the microtubule-binding protein tau. This
report concerns the ultrastructural localization of interfascicular threads and their relationship to coiled bodies in five
PSP patients. We showed for the first time that abnormal tubules with a 13- to 15-nm diameter and fuzzy outer contours were
the common structures of coiled bodies in the oligodendroglial perikarya and of interfascicular threads. Moreover, the tubules
were immunolabeled by anti-tau antibodies. The abnormal tau-positive tubules of interfascicular threads were located in the
inner loop of the myelin sheath. Our study further indicated that the thread-like structures in the white matter comprised,
at least in part, oligodendroglial processes, and that they were also present in gray matter. We consider that the formation
of coiled bodies in the perikarya and of interfascicular threads represents a common cytoskeletal abnormality of the oligodendroglia
of PSP patients. Moreover, even though the white matter alterations of PSP resemble those of corticobasal degeneration, there
are certain ultrastructural differences in the abnormal oligodendroglial tubules of the two diseases.
Received: 4 October 1996 / Accepted: 6 December 1996 相似文献
15.
H Iwanami M Saitoh K Narita M Tachibana K Hasegawa M Sakonzi E Tuboi 《Kyobu geka. The Japanese journal of thoracic surgery》1990,43(3):211-214
Of 200 lung cancer lesions resected in our hospital, there were 15 cases (7.5%) with middle lobe origin. The histological types were adenocarcinoma in 13 patients (4 patients with alveolar cell carcinoma), squamous cell carcinoma in one and large cell carcinoma in one. These patients were classified into two groups according to the type of operation they received and each group was evaluated. Group I (resection of the middle lobe) included 8 patients. Each one of Stage IIIB and Stage IV received the operation to improve their symptoms. The six patients of Stage I received only middle lobectomy as absolute curable cases. Group II (resection of the middle and lower lobes) included 7 patients, who had preoperative diagnosis of stage III. Two of them were postoperatively found to be cases of Stage I and Stage II. Although it was still short-term, the follow-up evaluation proved that these patients survived without local recurrence and distant metastasis, except for two with pleural dissemination and one with cerebral metastasis, who had received lobectomy as palliative operation. No difference was observed between the two groups receiving different types of operation. 相似文献
16.
K Kondoh S Sasaki T Oku S Minohara S Hasegawa Y Sawada M Morita A Takeuchi 《Kyobu geka. The Japanese journal of thoracic surgery》1992,45(7):565-9; discussion 569-72
In six hundred and six consecutive patients undergoing coronary artery bypass grafting (CABG) within the past 17 years (May 1974 to March 1991), repeated CABG were performed on 10 patients (1.65%). The main reasons for repeated CABG were graft failure (GF) in 8, progression of native disease (NP) in 5 and incomplete revascularization (IR) in 3 patients. The incidence of GF was high either within a half year or around 5 years after CABG. Although all patients survived from reoperation, four patients continued to have mild angina pectoris. When the recurrence of angina is noted after CABG, coronary arteriography and if necessary PTCA should be done as soon as possible. If a second surgery is inevitable, maximum utilization of arterial graft and accomplishment of complete revascularization are emphasized. 相似文献
17.
M Tsuchiya W Ueda M Tomoda E Takimoto K Furuno Y Kuzume H Kanaya T Hasegawa J Aono M Maesako 《Masui. The Japanese journal of anesthesiology》1990,39(7):915-917
The dynamic and functional state of soda lime can be more precisely assessed by measuring changes in wall temperatures of the absorption chambers rather than observing color change of the soda lime granules. We demonstrated in this report that the liquid crystal thermometer is an inexpensive and reliable measuring device for this purpose. 相似文献
18.
Antiherpes activity of chemically synthesized lipid A-subunit analogue GLA-60 in immunosuppressed mice 总被引:4,自引:0,他引:4
Intraperitoneal administration of 10 micrograms GLA-60, a chemically synthesized lipid A analogue, to mice one day after treatment with 200 mg/kg of cyclophosphamide (CY) significantly increased the number of macrophages, lymphocytes and polymorphonuclear leukocytes (PMNs) in the peritoneal cavity. The intrinsic antiviral activity of macrophages against herpes simplex virus type 1 (HSV-1) as well as natural killer (NK) activity against YAC-1 target cells was stimulated by administration of GLA-60 to CY-immunosuppressed mice. When the mice were administered GLA-60 prior to HSV-1 infection, virus growth was inhibited and the mortality rate of infected mice was reduced. Thus, GLA-60 is a potent immunomodulator achieving its antiviral action through enhancement of nonspecific host defense mechanisms. Combined treatment of GLA-60 with the antiviral agent acyclovir (ACV) resulted in greater protection against HSV-1 in the CY-immunosuppressed mice than did single treatment with either GLA-60 or ACV. 相似文献
19.
Clinical significance of selective middle hepatic venography 总被引:1,自引:0,他引:1
Selective middle hepatic venography was performed in 86 patients who had been scheduled to undergo liver resection because of hepatobiliary diseases. Special catheters were used of which tips were bended counterclockwise at an angle of 45 degrees. Successful middle hepatic venograms were obtained in 65 cases (76%). Abnormal findings were observed in 27 cases (42%), and it was difficult to diagnose them by ultrasonography or computed tomography. Selective middle hepatic venogram is very useful to understand surgical anatomy of the liver in each case preoperatively. In 5 cases of giant tumor, middle hepatic venography is necessary to identify the exact site of the tumor. Selective middle hepatic venography is considered to be one of the indispensable, examinations for liver resection. 相似文献
20.