全文获取类型
收费全文 | 15519篇 |
免费 | 752篇 |
国内免费 | 46篇 |
专业分类
耳鼻咽喉 | 168篇 |
儿科学 | 347篇 |
妇产科学 | 367篇 |
基础医学 | 2823篇 |
口腔科学 | 256篇 |
临床医学 | 1100篇 |
内科学 | 2126篇 |
皮肤病学 | 487篇 |
神经病学 | 1346篇 |
特种医学 | 1643篇 |
外科学 | 2013篇 |
综合类 | 93篇 |
一般理论 | 1篇 |
预防医学 | 1281篇 |
眼科学 | 161篇 |
药学 | 1443篇 |
中国医学 | 104篇 |
肿瘤学 | 558篇 |
出版年
2023年 | 110篇 |
2022年 | 106篇 |
2021年 | 273篇 |
2020年 | 186篇 |
2019年 | 260篇 |
2018年 | 384篇 |
2017年 | 270篇 |
2016年 | 346篇 |
2015年 | 298篇 |
2014年 | 418篇 |
2013年 | 628篇 |
2012年 | 1084篇 |
2011年 | 1460篇 |
2010年 | 676篇 |
2009年 | 342篇 |
2008年 | 1096篇 |
2007年 | 1216篇 |
2006年 | 1241篇 |
2005年 | 1024篇 |
2004年 | 923篇 |
2003年 | 905篇 |
2002年 | 736篇 |
2001年 | 391篇 |
2000年 | 492篇 |
1999年 | 294篇 |
1998年 | 114篇 |
1997年 | 77篇 |
1996年 | 54篇 |
1995年 | 72篇 |
1994年 | 38篇 |
1993年 | 29篇 |
1992年 | 29篇 |
1991年 | 31篇 |
1990年 | 36篇 |
1989年 | 31篇 |
1988年 | 25篇 |
1986年 | 19篇 |
1985年 | 31篇 |
1984年 | 24篇 |
1983年 | 25篇 |
1982年 | 35篇 |
1981年 | 30篇 |
1980年 | 30篇 |
1979年 | 28篇 |
1978年 | 29篇 |
1976年 | 21篇 |
1975年 | 26篇 |
1973年 | 18篇 |
1967年 | 19篇 |
1963年 | 19篇 |
排序方式: 共有10000条查询结果,搜索用时 578 毫秒
41.
S. Momčilović C. Cantacessi V. Arsić-Arsenijević D. Otranto S. Tasić-Otašević 《Clinical microbiology and infection》2019,25(3):290-309
Background
Parasitic diseases are one of the world's most devastating and prevalent infections, causing millions of morbidities and mortalities annually. In the past, many of these infections have been linked predominantly to tropical or subtropical areas. Nowadays, however, climatic and vector ecology changes, a significant increase in international travel, armed conflicts, and migration of humans and animals have influenced the transmission of some parasitic diseases from ‘book pages’ to reality in developed countries. It has also been noted that many patients who have never travelled to endemic areas suffer from blood-borne infections caused by protozoa. In the light of existing knowledge, this new trend can be explained by the fact that in the process of migration a large number of asymptomatic carriers become a part of the blood bank donor and transplant donor populations. Accurate and rapid diagnosis represents the crucial weapon in the fight against parasitic infections.Aims
To review old and new approaches for rapid diagnosis of parasitic infections.Sources
Data for this review were obtained through searches of PubMed using combinations of the following terms: parasitological diagnostics, microscopy, lateral flow assays, immunochromatographic assays, multiplex-PCR, and transplantation.Content
In this review, we provide a brief account of the advantages and limitations of rapid methods for diagnosis of parasitic diseases and focus our attention on current and future research in this area. The approximate costs associated with the use of different techniques and their applicability in endemic and non-endemic areas are also discussed.Implications
Microscopy remains the cornerstone of parasitological diagnostics, especially in the field and low-resource settings, and provides epidemiological assessment of parasite burden. However, increased use and availability of point-of-care tests and molecular assays in modern era allow more rapid and accurate diagnoses and increased sensitivity in the identification of parasitic infections. 相似文献42.
43.
Stevanović R Tiljak H Stanić A Varga S Not T Jovanović A 《Acta medica Croatica : c?asopis Hravatske akademije medicinskih znanosti》2005,59(3):267-271
A consensus reached by the medical profession, Croatian Institute of Health Insurance, Croatian Institute of Public Health, and Ministry of Health constitutes a solution to the problem of a data standard required in building an information system for primary health care. This consists of accepting ICPC-2 as a data standard for our Family Medicine, Pediatrics and Women's Health. The classification structure of the International Classification of Primary Care allows, recommends and urges that special codes be established by individual states or local authorities when registering patients' reasons for seeking medical aid or medical procedures. Namely, it urges the authorities to set the codes for such reasons about which a state or local agreement or determination has been made. This is the first public presentation of the proposal Croatia's Additions to the International Classification of Primary Care. They are essential to its implementation in our health insurance, health statistics and medical informatics. 相似文献
44.
Erceg M Stevanović R Babić-Erceg A 《Acta medica Croatica : c?asopis Hravatske akademije medicinskih znanosti》2005,59(3):245-249
Information production and its communication being a key public health activity, developing modern information systems is a precondition for its fulfilling these assignments. A national public health information system (NPHIS) is a set of human resources combined with computing and communication technologies. It enables data linkage and data coverage as well as undertaking information production and dissemination in an effective, standardized and safe way. The Croatian Institute of Public Health LAN/WAN modules are under development. Health Safety System, Health Workers Registry, and Digital Library are among the Institute's developmental priorities. Communication between NPHIS participants would unfold over the Internet by using every relevant data protection method. Web technology-based applications would be run on special servers. Between individual applications, use would be made of the transaction module of communication through an exchange of the HL7 standard-based xml messages. In the conditions of transition, the health system must make an optimal use of the resources, which is not feasible without applying modern information and communication technologies. 相似文献
45.
Zupanić-Krmek D Nemet D 《Acta medica Croatica : c?asopis Hravatske akademije medicinskih znanosti》2004,58(4):251-261
Opportunistic fungal infections are becoming more frequent complications during cancer therapy, after organ transplantation and in AIDS infections, especially after better control of bacterial infections in immunocompromised patients. Periods of prolonged neutropenia with neutrophil count less than 0.5 x 10(9)/L longer than 7 days, are the most important risk factors for the development of systemic fungal infections. Especially susceptible are the patients during treatment of acute leukemia, or after bone marrow transplantation. The most frequent causing agents of systemic fungal infections are Candida and Aspergillus species, than Cryptococcus neoformans and Mucor. Some other unusual species such Fusarium, Trichosporon, non-albicans Candida species of Candida are becoming more frequent, and is frequently resistant to conventional therapy. The difficulties in early and precise diagnosis of fungal infections, and the lack of adequate and efficient drugs are responsible for the high mortality of immunocompromised patients, even in potentially curable diseases. The recognition of risk factors, introduction of prophylactic measures, application of empirical antifungal therapy, are the procedures for the reduction of morbidity and mortality of invasive fungal infections. Fluconazole administration in prevention of systemic fungal infections, has become the standard approach, especially after bone marrow transplantation, while the oral itraconazole solution, has even more extended activity. Fluconazole appears successful also in the treatment of systemic Candidiasis. Conventional amphotericin-B is still the "gold standard" in the treatment of fungal infections. The new lipid formulations of amphotericin-B, intravenous itraconazole, has an identical efficacy, but are less toxic than conventional amphotericin-B. Several new promising agents are in the stage of clinical investigation like voriconazole, caspofungin, mycafungin and some other. 相似文献
46.
47.
Immune Responses to Bile-Tolerant Helicobacter Species in Patients with Chronic Liver Diseases, a Randomized Population Group, and Healthy Blood Donors 下载免费PDF全文
Olga Ananieva Ingrid Nilsson Tamara Vorobjova Raivo Uibo Torkel Wadstrm 《Clinical and Vaccine Immunology : CVI》2002,9(6):1160-1164
Bile-tolerant Helicobacter species such as Helicobacter pullorum, Helicobacter bilis, and Helicobacter hepaticus are associated with hepatic disorders in animals and may be involved in the pathogenesis of chronic liver diseases (CLD) in humans. Antibody responses to cell surface proteins of H. pullorum, H. bilis, and H. hepaticus in serum samples from patients with CLD, a randomized population group, and healthy blood donors were evaluated by using enzyme linked immunosorbent assay (ELISA). The results were compared with the antibody responses to Helicobacter pylori. For analysis of a possible cross-reactivity between bile-tolerant Helicobacter species and H. pylori, sera from a subpopulation of each group were absorbed with a whole-cell extract of H. pylori and retested by ELISA. Results before absorption showed that the mean value of the ELISA units for H. pullorum was significantly higher in patients with CLD than in healthy blood donors (P = 0.01). Antibody reactivity to cell surface protein of H. hepaticus was also significantly higher in the CLD patients than in the healthy blood donors and the population group (P = 0.005 and P = 0.002, respectively). Following the absorption, antibody responses to H. pullorum decreased significantly in all three groups (P = 0.0001 for CLD patients, P = 0.0005 for the population group, and P < 0.0001 for the blood donors), indicating that cross-reactivity between H. pylori and other Helicobacter spp. occurs. The antibody responses to H. hepaticus and H. bilis in CLD patients remained high following absorption experiments compared to ELISA results before absorption. The significance of this finding requires further investigations. 相似文献
48.
49.
50.
Vukić Z 《Croatian medical journal》2001,42(5):569-571
Left Bochdalek hernia is a serious and complex condition with high mortality. In most cases, it presents in the neonatal period and is seldom found later in life when symptomatology, usually after an asymptomatic period, is quite different and the prognosis excellent. The embryological development of left Bochdalek hernia suggests the presence of abdominal content in the left pleural cavity before birth. The type of clinical presentation and the prognosis depend on the time of visceral herniation. This study presents two cases of left Bochdalek hernia with delayed presentation. In both cases, after surgical reposition of the hernia, a small congenital diaphragmatic defect was found hidden between the rims of diaphragm. This indicates the possibility for the abdominal content to enter the left pleural cavity at the time of presentation. 相似文献