全文获取类型
收费全文 | 22802篇 |
免费 | 1637篇 |
国内免费 | 77篇 |
专业分类
耳鼻咽喉 | 375篇 |
儿科学 | 622篇 |
妇产科学 | 412篇 |
基础医学 | 2791篇 |
口腔科学 | 414篇 |
临床医学 | 2349篇 |
内科学 | 4894篇 |
皮肤病学 | 531篇 |
神经病学 | 1901篇 |
特种医学 | 785篇 |
外科学 | 3373篇 |
综合类 | 315篇 |
现状与发展 | 1篇 |
一般理论 | 21篇 |
预防医学 | 2081篇 |
眼科学 | 530篇 |
药学 | 1459篇 |
中国医学 | 25篇 |
肿瘤学 | 1637篇 |
出版年
2023年 | 123篇 |
2022年 | 224篇 |
2021年 | 500篇 |
2020年 | 314篇 |
2019年 | 469篇 |
2018年 | 592篇 |
2017年 | 411篇 |
2016年 | 452篇 |
2015年 | 512篇 |
2014年 | 749篇 |
2013年 | 1083篇 |
2012年 | 1535篇 |
2011年 | 1591篇 |
2010年 | 869篇 |
2009年 | 816篇 |
2008年 | 1349篇 |
2007年 | 1456篇 |
2006年 | 1419篇 |
2005年 | 1378篇 |
2004年 | 1393篇 |
2003年 | 1204篇 |
2002年 | 1085篇 |
2001年 | 286篇 |
2000年 | 274篇 |
1999年 | 308篇 |
1998年 | 298篇 |
1997年 | 210篇 |
1996年 | 178篇 |
1995年 | 183篇 |
1994年 | 162篇 |
1993年 | 149篇 |
1992年 | 183篇 |
1991年 | 180篇 |
1990年 | 152篇 |
1989年 | 164篇 |
1988年 | 149篇 |
1987年 | 137篇 |
1986年 | 146篇 |
1985年 | 136篇 |
1984年 | 137篇 |
1983年 | 100篇 |
1982年 | 107篇 |
1981年 | 133篇 |
1980年 | 109篇 |
1979年 | 109篇 |
1978年 | 86篇 |
1977年 | 83篇 |
1976年 | 74篇 |
1973年 | 77篇 |
1972年 | 71篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
Andy Waldhelm Sydney Allen Lacy Grand Carolyn Bopp Kristian Foster Ginger Muckridge Neil Schwarz 《International Journal of Sports Physical Therapy》2022,17(3):466
Background and PurposeAnterior cruciate ligament injuries are prevalent among the athletic population, imposing a heavy economic burden, and the risk of re-injury. Most current biomechanical screening tasks are performed in the sagittal plane, and there is a need for more screening tools that assess sports specific movements in the frontal plane. The purpose of this study was to determine the reliability of and examine differences between sexes in the performance of the Lateral Bound Test (LBT).Materials/MethodsEach subject performed three trials of a LBT which included jumping laterally from one leg over a hurdle and landing on the opposite leg. Two cameras were placed six feet from the landing marker. Maximum dynamic knee valgus using the frontal plane projection angle and knee flexion angle at initial contact and maximal knee flexion were measured upon landing leg using 2D video analysis software. Additionally, video of 10 individuals’ trials were analyzed twice with one week between the analyses to obtain intra-rater reliability while 12 participants were retested one week later to determine test-retest reliability.ResultsThirty healthy subjects, 16 males, 14 females participated. Intra-rater reliability was determined to be excellent for all variables (ICC>0.96). In contrast, the test-retest reliability had greater disparity. Test-retest reliability ranged from poor (ICC = 0.47) to excellent (ICC > 0.90). Significant differences existed between the sexes, including males being significantly taller, weighing more, and demonstrating greater bilateral dynamic knee valgus (p < 0.05). No significant differences existed between sexes for knee flexion angles.ConclusionThe new LBT had excellent intra-rater reliability for assessing dynamic knee valgus and initial and maximum knee flexion angle when performing a functional movement in the frontal plane. Furthermore, males landed with more dynamic knee valgus than females which is contradictory to what has been observed with functional screening tools performed in the sagittal plane.Level of Evidence3b (reliability study) 相似文献
992.
By use of an in vitro experimental system which permits the observation at high resolution of articular cartilage in a physiologic condition, its biomechanical response to compression was investigated before and after enzymatic digestion of the proteoglycan components with testicular hyaluronidase. The study provides further insight into the functional interplay between the collagen network and the hydrated proteoglycans. Certain structural features associated with age-related and osteoarthritic changes occurring in vivo in human articular cartilage were mimicked in the compressive response of the enzymatically digested tissue. 相似文献
993.
Cheneau E Wu Z Leborgne L Ajani AE Weissman N Pichard AD Satler LF Kent KM Mintz G Waksman R 《American heart journal》2003,146(1):142-145
Background
Vascular brachytherapy (VBT) reduces in-stent restenosis (ISR). However, additional stenting at the time of radiation may be associated with a worse outcome.Methods and results
Intravascular ultrasound (IVUS) was performed after VBT and at 6 months follow-up in 79 native artery ISR patients treated with γ-radiation who participated in the Washington Radiation for In-Stent restenosis Trial (WRIST), Gamma-1, and Angiorad Radiation Technology for In-Stent restenosis Trial in Coronaries (ARTISTIC) trials. Patients were treated with 192Ir at 14 or 15 Gy at 2 mm from the source. Additional stents were used to treat the ISR lesions in 45 patients; these patients were then compared with the 34 patients treated without restenting. Paired measurements included stent, lumen, and intimal hyperplasia volumes. After the VBT procedure, intimal hyperplasia volume was smaller in the group treated with additional stents (54 ± 33 mm3 vs 34 ± 33 mm3, P = .012), but minimal lumen area was similar between the 2 groups (4.3 ± 1.5 mm2 vs 4.7 ± 1.4 mm2 respectively, P = NS). Between the time of the VBT procedure and follow-up, intimal hyperplasia volume increased by 27 ± 19 mm3 in the restented group and by 9 ± 21 mm3 in the group treated without additional stents (P = .014). At 6 months, intimal volume was similar in the 2 groups, but minimal lumen area was slightly smaller in the group treated with additional stents (3.4 ± 1.8 mm2 vs 4.2 ± 1.7 mm2, P = .053). Patients treated with additional stents had more target lesion revascularizations than the group treated without additional stents (38% vs 15%, P = .02).Conclusions
Additional stenting reduces intimal hyperplasia within the stents acutely. However, it compromises the benefit of VBT by promoting higher intimal regrowth within months after radiation. 相似文献994.
Fickelscher I Starke H Schulze E Ernst G Kosyakova N Mkrtchyan H MacDermont K Sebire N Liehr T 《Prenatal diagnosis》2007,27(8):783-785
A prenatally ascertained case with a de novo small supernumerary marker chromosome (sSMC) derived from chromosome 1 is reported. Due to a fetal heart defect the parents decided in favour of an induced abortion. Postmortem, a molecular cytogenetic study on eleven formalin fixed, paraffin-embedded tissues of the fetus was performed, to further characterize the levels of mosaicism of the sSMC(1). sSMC presence varied between 13 and 62% within different tissues of sSMC carriers. This finding is something common in sSMC carriers and could explain why up to the present no clinical correlations for sSMC mosaicism and clinical outcome in the corresponding carriers could be established. 相似文献
995.
BACKGROUND: The purpose of this case report is to describe the first experience with erlotinib (Tarceva) in the treatment of locally advanced vulvar cancer. CASE: Two elderly patients presented with locally advanced vulvar cancer. Surgery was not a suitable method of treatment for either of them because of multiple medical co-morbidities and stage of disease. One patient had disease progression on standard chemoradiation. Erlotinib, an oral epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, was tried in both cases and dramatic responses were observed. CONCLUSION: Therapy targeted to EGFR may be effective in the treatment of locally advanced vulvar cancer. This new therapeutic approach deserves further evaluation in carefully designed studies. 相似文献
996.
997.
998.
Neil Hudson Nigel Stansbie Susan Rhind Gillian Brown Ian Handel Richard Mellanby 《Medical teacher》2016,38(2):208-210
A key responsibility of healthcare professionals is the education of clients/patients, colleagues and students undertaking placements. Peer-assisted learning (PAL) has been incorporated in our veterinary medicine programme for a number of years. The aim of this project was to develop a mechanism to formally recognise the important role that students play in the School’s teaching and learning processes and foster students as partners in education through the development of a novel Undergraduate Certificate in Veterinary Medical Education (UCVME). Students and veterinarians were surveyed in order to inform the design of the programme. The programme is modular and aligned with the UK Professional Standards Framework (UKPSF). Students enrol in their third year, undertaking core and elective components, with completion over the final three years of the degree. The UCVME has been positively received, with 30 of 160 third year students enrolling in the programme’s first year. Activities receiving credit and designed in partnership between staff and students have included: PAL sessions, widening participation school educational workshops and client education events. This initiative has created numerous student-driven educational opportunities. It is hoped that this programme will facilitate the educational training of students and enhance employability and career satisfaction. 相似文献
999.
Lilia R. Lukowsky Claudia Der-Martirosian William Neil Steers Kiran S. Kamble Aram Dobalian 《Viruses》2022,14(2)
Background. Previous studies examining the early spread of COVID-19 have used influenza-like illnesses (ILIs) to determine the early spread of COVID-19. We used COVID-19 case definition to identify COVID-like symptoms (CLS) independently of other influenza-like illnesses (ILIs). Methods. Using data from Emergency Department (ED) visits at VA Medical Centers in CA, TX, and FL, we compared weekly rates of CLS, ILIs, and non-influenza ILIs encounters during five consecutive flu seasons (2015–2020) and estimated the risk of developing each illness during the first 23 weeks of the 2019–2020 season compared to previous seasons. Results. Patients with CLS were significantly more likely to visit the ED during the first 23 weeks of the 2019–2020 compared to prior seasons, while ED visits for influenza and non-influenza ILIs did not differ substantially. Adjusted CLS risk was significantly lower for all seasons relative to the 2019–2020 season: RR15–16 = 0.72, 0.75, 0.72; RR16–17 = 0.81, 0.77, 0.79; RR17–18 = 0.80, 0.89, 0.83; RR18–19 = 0.82, 0.96, 0.81, in CA, TX, and FL, respectively. Conclusions. The observed increase in ED visits for CLS indicates the likely spread of COVID-19 in the US earlier than previously reported. VA data could potentially help identify emerging infectious diseases and supplement existing syndromic surveillance systems. 相似文献
1000.