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41.
1986~1992年我院共收治急性发作期慢性肺心病196例,其中因严重肺部感染发生多器官衰竭(MOF)者70例(35.7%),平均受损脏器2.5个,死亡26例,总病死率为37.1%。其中2和3个脏器受损者的病死率分别为20.1%和44.4%,而4和5个脏器受损者则均死亡。血气分析显示pH和PaO2值与受损脏器数目呈负相关,而PaCO2值与受损脏器数目呈正相关。本文讨论了肺心病因肺部感染并发MOF的发病机理,并提出防治的措施。 相似文献
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J Suárez de Lezo A Medina M Pan E Hernández M Sancho A Bethencourt M Romero F Melián J Segura F Jiménez 《Revista espa?ola de cardiología》1991,44(2):106-114
We study 40 patients, 55 +/- 7 years old with acute myocardial infarction treated early by thrombolytic therapy (20 STK and 20 rt-PA). All patients were angiographically studied in the following conditions: 1) baseline, before initiating therapy. 2) Three hours after treatment. 3) Twenty four hours later. 4) Before discharge. The infarct related artery was patent 24 hours after treatment in 31 patients (78%); five of them were patent before treatment, and we observed an early reperfusion in 20 patients (57%) and late reperfusion in 6 patients (17%). The number of patients with angiographic evidence of intraluminal thrombus decreased progressively through conditions while the grade TIMI of coronary perfusion increased in the absence of reocclusion. Final regional wall motion of infarct related myocardial zones and their degree of recovery were significantly higher in recanalized patients, as compared with non-reperfused patients. Similarly, left ventricular functional recovery was higher in patients with antegrade of collateral flow to the infarct area, as compared with totally occluded patients. 相似文献
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W A Gomes F A Lado N C de Lanerolle K Takahashi C Pan H P Hetherington 《Magnetic resonance in medicine》2007,58(2):230-235
Reduced hippocampal N-acetyl aspartate (NAA) is commonly observed in patients with advanced, chronic temporal lobe epilepsy (TLE). It is unclear, however, whether an NAA deficit is also present during the clinically quiescent latent period that characterizes early TLE. This question has important implications for the use of MR spectroscopic imaging (MRSI) in the early identification of patients at risk for TLE. To determine whether NAA is diminished during the latent period, we obtained high-resolution (1)H spectroscopic imaging during the latent period of the rat pilocarpine model of human TLE. We used actively detuneable surface reception and volume transmission coils to enhance sensitivity and a semiautomated voxel shifting method to accurately position voxels within the hippocampi. During the latent period, 2 and 7 d following pilocarpine treatment, hippocampal NAA was significantly reduced by 27.5 +/- 6.9% (P < 0.001) and 17.3 +/- 6.9% (P < 0.001) at 2 and 7 d, respectively. Quantitative estimates of neuronal loss at 7 d (2.3 +/- 7.7% reduction; P = 0.58, not significant) demonstrate that the NAA deficit is not due to neuron loss and therefore likely represents metabolic impairment of hippocampal neurons during the latent phase. Therefore, spectroscopic imaging provides an early marker for metabolic dysfunction in this model of TLE. 相似文献
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目的观察无抽搐电痉挛(Modified Electrocnvulsive therapy,MECT)治疗精神分裂症的疗效及给予次数的关系。方法将60例诊断为精神分裂症的住院患者按治疗次数随机分为两组,进行MECT的临床资料总结分析。结果治疗次数≥6次组,显效率为83.3%,次数〈6次组显效率为76.7%,两者显效率无显著性差异(P〉0.05),每组治疗前后BPRS评分有显著差异,但两组间比较无显著差异(P〉0.05),未发现严重不良反应。结论MECF安全性高,有一定疗效,与治疗次数关系不大。 相似文献
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Angelo Pan Placido Mondello Klara Posfay-Barbe Patrizia Catenazzi Annise Grandi Silvia Lorenzotti Andrea Patroni Nadia Poli Laura Soavi Giuseppe Carnevale 《Infection control and hospital epidemiology》2007,28(9):1099-1102
In an Italian hospital, we observed that hand hygiene was performed in 638 (19.6%) of 3,253 opportunities, whereas gloves were worn in 538 (44.2%) 1,218 of opportunities. We observed an inverse correlation between the intensity of care and the rate of hand hygiene compliance (R2=0.057; P<.001), but no such association was observed for the rate of glove use compliance (R2=0.014; P=.078). Rates of compliance with hand hygiene and glove use recommendations follow different behavioral patterns. 相似文献
49.
对人胎儿前庭器超微结构的研究,国内外报道甚少。本文对18至36周人胎儿颞骨10具进行了扫描电镜和透射电镜的观察,并对应用Surface preparation法制做人胎儿前庭器标本的方法进行了探讨。本文观察所见:豚鼠平衡斑的生理状态与人胎儿很近似,体面积比人胎儿平衡斑小,感觉毛长,细胞排列更整齐。28周以后的胎儿因前庭周围骨质变硬,制做标本时可以分别取出两囊斑和壶腹嵴。 相似文献
50.
重症肌无力患者泼尼松治疗前后免疫学指标的变化 总被引:3,自引:0,他引:3
探讨泼尼松治疗重症肌无力(MG)免疫学机制。对382例MG患者在漏尼松中剂量冲击,小剂量维持疗法治疗前后,检测酰胆碱受体抗炎(AchRab),突触前膜抗体(PsMab),单个核细胞亚群(PBMC),肿瘤坏死因子(TNF),可溶性白介素-2受体(SIL-2R),β2-微球蛋白(β2-m),以及红细胞免疫功能的变化。结果表明:MG患者在泼尼松治疗前后多项免疫指标有显著性的变化。为泼尼松治疗MG提供了评定疗效的免疫学指标,进一步阐明了MG发病的免疫学机制。 相似文献