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排序方式: 共有612条查询结果,搜索用时 15 毫秒
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Esther Abels Liron Pantanowitz Famke Aeffner Mark D Zarella Jeroen van der Laak Marilyn M Bui Venkata NP Vemuri Anil V Parwani Jeff Gibbs Emmanuel Agosto-Arroyo Andrew H Beck Cleopatra Kozlowski 《The Journal of pathology》2019,249(3):286-294
In this white paper, experts from the Digital Pathology Association (DPA) define terminology and concepts in the emerging field of computational pathology, with a focus on its application to histology images analyzed together with their associated patient data to extract information. This review offers a historical perspective and describes the potential clinical benefits from research and applications in this field, as well as significant obstacles to adoption. Best practices for implementing computational pathology workflows are presented. These include infrastructure considerations, acquisition of training data, quality assessments, as well as regulatory, ethical, and cyber-security concerns. Recommendations are provided for regulators, vendors, and computational pathology practitioners in order to facilitate progress in the field. © 2019 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of Pathological Society of Great Britain and Ireland. 相似文献
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Phase 2 trial of neoadjuvant chemotherapy and transoral endoscopic surgery with risk‐adapted adjuvant therapy for squamous cell carcinoma of the head and neck
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97.
Phase 1b study of pasireotide,everolimus, and selective internal radioembolization therapy for unresectable neuroendocrine tumors with hepatic metastases
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98.
SARC009: Phase 2 study of dasatinib in patients with previously treated,high‐grade,advanced sarcoma
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Scott M. Schuetze MD PhD J. Kyle Wathen PhD David R. Lucas MD Edwin Choy MD PhD Brian L. Samuels MD Arthur P. Staddon MD Kristen N. Ganjoo MD Margaret von Mehren MD Warren A. Chow MD David M. Loeb MD PhD Hussein A. Tawbi MD PhD Daniel A. Rushing MD Shreyaskumar R. Patel MD Dafydd G. Thomas MD PhD Rashmi Chugh MD Denise K. Reinke NP MBA Laurence H. Baker DO 《Cancer》2016,122(6):868-874
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What's the diagnosis? Organisational culture and palliative care delivery in residential aged care in New Zealand
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Rosemary Frey PhD Michal Boyd PhD Sue Foster MSW Jackie Robinson RN NP Prof. Merryn Gott 《Health & social care in the community》2016,24(4):450-462
Organisational culture has been shown to impact on resident outcomes in residential aged care (RAC). This is particularly important given the growing number of residents with high palliative care needs. The study described herein (conducted from January 2013 to March 2014) examined survey results from a convenience sample of 46 managers, alongside interviews with a purposively selected sample of 23 bereaved family members in order to explore the perceptions of organisational culture within New Zealand RAC facilities in one large urban District Health Board. Results of the Organisational Culture Assessment Instrument (OCAI) completed by managers indicated a preference for a ‘Clan’ and the structured ‘Hierarchy’ culture. Bereaved family interviews emphasised both positive and negative aspects of communication, leadership and teamwork, and relationship with residents. Study results from both managers’ OCAI survey scores and next of kin interviews indicate that while the RAC facilities are culturally oriented towards providing quality care for residents, they may face barriers to adopting organisational processes supportive of this goal. 相似文献
100.
Robert Dart MD Linda Dart RN Patricia Mitchell RN Nancy O'Rourke RN NP 《Academic emergency medicine》1999,6(10):1024-1029
OBJECTIVES: To ascertain the overall frequency of obtaining chorionic villi (CV) in patients with indeterminate transvaginal ultrasound (US) examinations who have had a dilatation and evacuation (D+E) procedure performed, to determine whether the frequency of obtaining CV is dependent on whether the endometrial cavity is empty at US, and to determine the likelihood of ectopic pregnancy in patients without CV after D+E and with or without an empty endometrial cavity at US. METHODS: A retrospective review was made of consecutive ED patients presenting to an urban teaching hospital from August 1991 through August 1997 with abdominal pain or vaginal bleeding and a positive beta-human chorionic gonatropin (beta-hCG) test. Patients who had a transvaginal US that was read as indeterminate (no extrauterine findings of ectopic pregnancy, and no intrauterine fetal pole or yolk sac) and who had a D+E performed within 48 hours of the ED visit were eligible. US exams were subdivided into two groups, those with empty endometrial cavities and those with endometrial cavities that contained fluid, echogenic material, or sac-like structures. The presence or absence of CV was based on the official pathology report. Patients were excluded if pathology results were not available. RESULTS: A total of 255 patients met eligibility criteria. Of these, pathology results were not available for five patients. Of the remaining patients, 177 of 250 (70.8%: 95% CI = 64.7% to 76.3%) had CV identified in the pathology specimen. The difference in the frequencies of obtaining CV in those with empty endometrial cavities (35/78; 44.9%: 95% CI = 34% to 56%) vs. those without empty endometrial cavities (142/172; 82.6%: 95% CI = 76% to 88%) was significant (p<0.001). Ectopic pregnancy was diagnosed in 17 of 42 (40.0%) with empty uteri at US and no CV at pathology vs 5 of 26 (19.2%) in whom the uterus was not empty and no CV were obtained (p = 0.07). CONCLUSION: In symptomatic patients with indeterminate transvaginal ultrasound exams, CV will be identified after D+E in approximately 70% of cases. Although CV were found with increased frequency when the endometrial cavity was not empty, still almost half of the patients with empty uteri had villi identified. Finally, although the frequency of ectopic pregnancy was higher in the patients with empty uteri and no CV at D+E, vs. those without an empty uterus and no CV, this difference did not reach statistical significance. 相似文献