Demonstration, by the cartographic test, of an unusual reaction to intermittent light stimulation in patients with migraine

Topographic electroencephalography was carried out to study reaction to photic stimulation in 29 normal volunteers, and 12 patients who had presented frequent clinically confirmed migraines for at least 3 years. In the group of migraineurs photic stimulation resulted in an increase in the alpha band power. The difference between the two groups was statistically significant. This reaction to photic stimulation is of help in diagnosis and suggests that a diagnosis and therapeutic orientation might be possible in patients for whom clinical diagnosis is not clear. The specificity of the migraineur's reaction to photic stimulation and its possible origin are discussed.     

Radiological findings in 1135 edentulous patients

A sample consisting of 1135 edentulous patients with clinically healthy denture bearing areas, was examined radiologically. It appears that the diagnostic yield is high whereas the expected radiation induced risk is low. Patients should therefore be examined radiologically prior to full denture construction.     

C-reactive protein as a predictor of fetal and maternal infective morbidity and fetal mortality

The value of maternal C-reactive protein (CRP) levels as predictors of fetal and maternal infective morbidity and fetal mortality was assessed prospectively over a 6-month period in all cases of premature rupture of the fetal membranes or suspected premature labour. Statistical analysis of results showed that CRP at a level of 1.32 mg/dl is a sensitive marker of infective morbidity in mother and neonate. Furthermore, there was a significant association between raised CRP levels and low-birth-weight babies, suggesting that intra-uterine infection is a major cause of prematurity in the study population.     

346. Die bedeutung von stenosen an gefä\verzweigungen. eine experimentelle untersuchung an der femoralisgabel unter besonderer berücksichtigung der indikation zur profundaplastik

Zusammenfassung In einem pulsatil mit Kochsalz durchströmten Modell der Femoralisgabel wurden Flussmessungen und Druckgradienten für Flussmengen von 170 bis 860 ml/min bei peripheren Widerständen von 232 bis 25 792 dyn s cm^–5 über dem Superficialis- und Profundaabgang bei Stenosen von 1 cm Länge und Querschnittsverminderungen von 0% bis 100% gemessen. Bei grossen Flussmengen (800–860 ml/min) und kleinem peripheren Widerstand (<640 dyn s cm^–5) lag die kritische Stenose am Profundaabgang bei 4,1 mm Durchmesser, für hohe periphere Widerstände (> 5 072 dyn s cm^–5) bei 2,6 mm; bei kleinen Flussmengen (<400 ml/min) betrug der kritische Durchmesser 1,8 mm. Der nicht stenosierte Profundaabgang stellte für keine der Versuchsbedingungen ein strömungsdynamisches Hindernis dar.     

Renal Aspergilloma--A Case Illustrating the Problems of Medical Therapy

The second documented case of renal aspergilloma due to Aspergillusflavus is presented. The merits of the medical therapy thatfailed are discussed. Pathological examination showed a nidusof aspergillus around suture material persisting from a pyelolithotomyoperation 2 years before in India. We argue that this was thereason for the failure of the medical therapy. This is the firstcase of its kind reported.     

Rapid action of 1,25-dihydroxyvitamin D3 on calcium transport in perfused chick duodenum: effect of inhibitors

Transport of 45Ca from the lumen to the venous effluent was studied in duodena of normal, vitamin D3-replete (+D) chicks perfused through the celiac artery with 130 pM 1,25(OH)2D3 or vehicle. Administration of actinomycin D 3 h prior to perfusion did not alter the unstimulated transport rate or diminish the response to exogenous 1,25(OH)2D3: After 40 min exposure to the seco-steroid, 45Ca in the vascular effluent was 140% of control levels. The anti-microfilament agent cytochalasin b and the ionophore monensin, an inhibitor of Golgi function, similarly failed to suppress 1,25(OH)2D3-stimulated calcium transport. In pilot studies, Golgi and basal-lateral membrane fractions were prepared from duodenal epithelium of vitamin D-deficient (-D) chicks treated with vehicle or 650 pmol of 1,25(OH)2D3 in vivo 2 h, 10 h, or 15 h before sacrifice, as well as from +D birds. Analyses of Golgi fractions for cathepsin B (CB) activity revealed a biphasic response with time, increasing to 200% of -D levels 2 h after 1,25(OH)2D3 administration and in equivalent preparations from +D birds. Less pronounced increases in acid phosphatase activity were observed in the same membrane fractions. In basal-lateral membranes, enhanced CB activity was detectable 10 h after 1,25(OH)2D3 in vivo, rose to 155% of -D levels at 15 h, and to 245% of controls in fractions from +D birds, whereas acid phosphatase was 75%, 81%, and 125% of controls, respectively, at these times.(ABSTRACT TRUNCATED AT 250 WORDS)