Study on Photocatalytic Performance of Ag/TiO2 Modified Cement Mortar

In this paper, Ag-TiO₂ photocatalysts with different Ag contents (1 mol%–5 mol%) were prepared and applied to cement mortar. The photocatalytic performance of Ag-TiO₂ and photocatalytic cement mortar under UV light and simulated solar light was evaluated. The results showed that Ag loading on the surface of TiO₂ could reduce its band gap width and increase its absorbance in the visible region, and 2% Ag-TiO₂ had the highest photocatalytic activity under UV light, the degradation rate of methyl orange (MO) was 95.5% at 30 min, and the first-order reaction constant k was 0.0980 min⁻¹, which was 61.7% higher than that of TiO₂, and 5% Ag-TiO₂ had the highest photocatalytic activity under solar light, the degradation rate of methylene blue (MB) was 69.8% at 40 min, and the first-order reaction constant k was 0.0294 min⁻¹, which was 90.9% higher than that of TiO₂. The photocatalytic mortar prepared by the spraying method has high photocatalytic performance, The MO degradation rate of sample S2 under UV light was 87.5% after 120 min, MB degradation rate of sample S5 under solar light was 75.4% after 120 min. The photocatalytic reaction conforms to the zero-order reaction kinetics, which was 1.5 times–3.3 times higher than that of the mixed samples and has no effect on the mechanical properties of mortar.     

宫颈癌中医分期辨治研究进展

运用中医学理论,结合现代医学,从中医分期辨证的角度出发,对宫颈癌前病变期、围手术期、放化疗期3个阶段进行概述.根据宫颈癌形成、发展的不同时期,治疗上第一阶段应侧重祛邪为主,佐以补虚;第二阶段应补虚与祛邪并重,同时注重术后并发症的预防与治疗;第三阶段着重扶助正气,兼顾他症.倡导中医药使用不同的治法进行分期论治,提高人们对...     

miR-191及miR-886-5p在肺结核外周血中的表达与临床价值研究

目的研究miR-191、miR-886-5p在肺结核外周血中的表达与临床价值。方法选取2019年1月至2020年8月在武汉市新洲区人民医院确诊为肺结核的患者50例作为结核组,潜伏感染结核杆菌的患者50例作为潜在感染组,选取同期在武汉市新洲区人民医院体检的健康者50例作为对照组。所有入组受试者于清晨空腹采集2 mL静脉血,采用RNA试剂盒提取循环RNA,定量计算miR-191、miR-886-5p的表达水平。利用Person相关性分析肺结核患者miR-191、miR-886-5p表达与年龄、性别、肺部病灶个数、空洞个数的相关性,构建logistic回归分析模型分析肺结核发生的危险因素。结果对照组、潜在感染组、肺结核组患者miR-191水平依次降低,而miR-886-5p水平依次升高,差异有统计学意义(P<0.05)。肺结核患者miR-191、miR-886-5p表达水平与肺部病灶个数、空洞个数呈正相关(P<0.05),与年龄、性别不具相关性(P>0.05)。ROC曲线表明miR-191、miR-886-5p在诊断肺结核都有意义,miR-191、miR-886-5p联合诊...     

长春胺对非动脉炎性前部缺血性视神经病变大鼠模型视神经保护作用及其机制

目的：研究长春胺对非动脉炎性前部缺血性视神经病变（NAION）大鼠模型的潜在神经保护作用。方法：90只SD大鼠随机分为正常组、单纯模型组、造模羧甲基纤维素钠灌胃组（NaCMC)组、长春胺组、造模PI3K抑制剂LY294002玻璃体腔注射(IVT LY)+长春胺组、造模DMSO玻璃体腔注射（IVT DMSO)+长春胺组。对各组进行眼底照相,眼底荧光血管造影,血清一氧化氮（NO）浓度检测,HE染色观察视网膜形态,甲苯胺蓝染色观察视神经轴突形态,免疫荧光染色计数视网膜神经节细胞（RGCs）,实时定量PCR检测p-AKT、eNOS含量。结果：rNAION大鼠（rNAION）造模成功后第1天即可见大鼠视盘水肿,边界模糊。造模后第28天,长春胺组的NO浓度显著高于正常对照组、单纯模型组及NaCMC组。与单纯模型组相比,长春胺组RGCs数量明显增加（P<0.05）,pAKT、eNOS含量明显增加（P<0.05）。IVT LY+长春胺组RGCs数量及p-AKT、eNOS含量较长春胺组明显减少（P<0.05）。结论：长春胺可能通过PI3K/AKT/eNOS信号通路发挥视神经保护作用,有...     

芜湖市弋江区2009～2013年法定报告传染病流行特征分析

弋江区位于芜湖市中部,属于城乡结合部,辖区内7所高校,在校学生数约7万人,外来务工人口较多。传染病是危害人类健康的主要疾病,与社会经济发展和卫生保健事业水平息息相关[1]。为了解2009-2013年弋江区法定报告传染病的流行规律,探索传染病的流行特点及影响因素,为对今后制定传染病防控策略提供科学依据,现对弋江区2009~2013年法定报告传染病资料进行分析。1材料与方法     

Exposure to Per- and Polyfluoroalkyl Substances and Mortality in U.S. Adults: A Population-Based Cohort Study

Background: Per- and polyfluoroalkyl substances (PFAS) are widespread environmental contaminants associated with diseases such as cancer and dyslipidemia. However, few studies have investigated the association between PFAS mixture exposure and mortality in general populations.Objectives: This study aimed to explore the association between PFAS mixture, perfluorooctanoic acid (PFOA), and perfluorooctane sulfonic acid (PFOS) and mortality in U.S. adults by a nationally representative cohort.Methods: Adults ≥18 years of age who were enrolled in the National Health and Nutrition Examination Survey (NHANES) (1999–2014) were included in our study. Baseline serum concentrations of seven PFAS were measured and individuals were followed up to 31 December 2015. Hazard ratios (HRs) and confidence intervals (CIs) were estimated using Cox proportional hazards models. Association between PFAS mixture exposure and mortality was analyzed using the k-means method by clustering PFAS mixtures into subgroups. Association between PFOA/PFOS exposure and mortality was subsequently analyzed in both continuous and categorical models.Results: During the follow-up period, 1,251 participants died. In the mixture analysis, the k-means algorithm clustered participants into low-, medium-, and high-exposure groups. Compared with the low-exposure group, participants in the high-exposure group showed significantly higher risks for all-cause mortality (HR=1.38; 95% CI: 1.07, 1.80), heart disease mortality (HR=1.58; 95% CI: 1.05, 2.51), and cancer mortality (HR=1.70; 95% CI: 1.08, 2.84). In single PFAS analysis, PFOS was found to be positively associated with all-cause mortality (third vs. first tertile HR=1.57; 95% CI: 1.22, 2.07), heart disease mortality (third vs. first tertile HR=1.65; 95% CI: 1.09, 2.57), and cancer mortality (third vs. first tertile HR=1.75; 95% CI: 1.10, 2.83), whereas PFOA exposure had no significant association with mortality. Assuming the observed association is causal, the number of deaths associated with PFOS exposure (≥17.1 vs. <7.9 ng/mL) was ∼382,000 (95% CI: 176,000, 588,000) annually between 1999 and 2015, and it decreased to 69,000 (95% CI: 28,000, 119,000) annually between 2015 and 2018. The association between PFOS and mortality was stronger among women and people without diabetes.Discussion: We observed a positive association between PFAS mixture exposure and mortality among U.S. adults. Limitations of this study include the potential for unmeasured confounding, selection bias, a relatively small number of deaths, and only measuring PFAS at one point in time. Further studies with serial measures of PFAS concentrations and longer follow-ups are necessary to elucidate the association between PFAS and mortality from specific causes. https://doi.org/10.1289/EHP10393     

脑卒中患者医院-家庭过渡期护理的研究进展

对过渡期护理的概念、脑卒中患者医院-家庭过渡期护理发展现状、我国脑卒中患者过渡期护理存在问题及顺利过渡的改善策略等进行综述,旨在为构建适合我国脑卒中患者的过渡期护理模式、护理方案提供依据,为更好地维护并促进脑卒中患者的康复和健康提供借鉴。     

乌索酸对S-180肉瘤小鼠的抑瘤作用及其机制

目的:研究乌索酸(UA)对S-180肉瘤小鼠抑瘤作用及其可能机制。方法:建立小鼠S-180肉瘤模型,以灌胃方式给药。乌索酸连续灌胃治疗9 d,测量体质量、瘤重、脾重;计算抑瘤率及脾指数;光镜下观察组织结构的变化;流式细胞仪检测乌索酸对肉瘤鼠免疫功能、细胞周期和细胞凋亡的影响。结果:乌索酸对S-180肉瘤小鼠抑瘤率为62.82%,脾指数较生理盐水组增加。光镜下可见大片坏死及凋亡细胞。流式细胞仪分析显示乌索酸具有调节免疫功能的作用;使肿瘤细胞阻滞在S期;肿瘤细胞凋亡率达到24.17%。结论:乌索酸可显著抑制肿瘤生长,其抗肿瘤机制可能与提高机体免疫功能、肿瘤细胞S期阻滞及诱导其凋亡有关。     

脾内动脉吻合的临床意义初探

目的:探讨脾内动脉吻合与部分脾栓塞术(PSE) 及部分脾切除术的关系。材料与方法:回顾性分析110 例脾动脉造影病例,着重观察脾内动脉吻合的出现率、吻合形式、部位及吻合点远端脾动脉分支直径。结果:脾内动脉吻合的显示率为22-7 % ,其中叶间吻合10 % 、段间吻合7-3 % 。吻合形式分为短交通支吻合、弓形吻合、汇集型吻合三种。吻合点远端脾动脉分支直径≤1m m 者占5-5 % 。结论:若采用1m m3( 或以下) 容积的栓塞剂行PSE 术,栓塞剂绝大部分滞留在吻合点远端的脾动脉分支内,吻合动脉不能向被栓塞的脾实质供血。但行部分性脾切除术时,应警惕叶间、段间吻合动脉的出现并慎重处理这些吻合动脉。     

脑脊液细胞学在蛛网膜下腔出血中的应用价值

目的：应用细胞玻片离心仪和50例蛛网膜下腔出血（SAH）患者进行了不同时期脑脊液细胞学检查。方法：常规抽取脑脊液,经FMU-5细胞玻片离心仪直接离心制片,进行MGG染色,进行细胞分类。结果：蛛网膜下腔出血后脑脊液中白细胞在不同时期的细胞特征是：急性期：大量红细胞及高比例的嗜中性粒细胞期,嗜中性粒细胞比率在70%以上,48～72 h达高峰,一周后逐渐消失。吸收期：激活单核细胞增多,可出现红细胞吞噬细胞及特征性细胞-含铁血黄素吞噬细胞,持续2～3周。恢复期：主要以激活单核细胞为主,持续数周或几月。结论：应用该法进行脑脊液细胞学检查,可给临床提供一个直观、准确的诊断依据。对蛛网膜下腔出血病人的病理学监测、鉴别诊断和治疗具有重要价值。