全文获取类型
收费全文 | 3340篇 |
免费 | 159篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 27篇 |
儿科学 | 47篇 |
妇产科学 | 28篇 |
基础医学 | 516篇 |
口腔科学 | 83篇 |
临床医学 | 221篇 |
内科学 | 900篇 |
皮肤病学 | 54篇 |
神经病学 | 217篇 |
特种医学 | 108篇 |
外科学 | 433篇 |
综合类 | 30篇 |
预防医学 | 136篇 |
眼科学 | 30篇 |
药学 | 329篇 |
中国医学 | 5篇 |
肿瘤学 | 350篇 |
出版年
2023年 | 13篇 |
2022年 | 38篇 |
2021年 | 68篇 |
2020年 | 38篇 |
2019年 | 50篇 |
2018年 | 49篇 |
2017年 | 44篇 |
2016年 | 43篇 |
2015年 | 36篇 |
2014年 | 62篇 |
2013年 | 85篇 |
2012年 | 120篇 |
2011年 | 157篇 |
2010年 | 101篇 |
2009年 | 81篇 |
2008年 | 173篇 |
2007年 | 203篇 |
2006年 | 181篇 |
2005年 | 204篇 |
2004年 | 193篇 |
2003年 | 188篇 |
2002年 | 208篇 |
2001年 | 81篇 |
2000年 | 80篇 |
1999年 | 82篇 |
1998年 | 69篇 |
1997年 | 43篇 |
1996年 | 42篇 |
1995年 | 27篇 |
1994年 | 38篇 |
1993年 | 36篇 |
1992年 | 64篇 |
1991年 | 61篇 |
1990年 | 52篇 |
1989年 | 45篇 |
1988年 | 46篇 |
1987年 | 45篇 |
1986年 | 39篇 |
1985年 | 29篇 |
1984年 | 29篇 |
1983年 | 27篇 |
1982年 | 14篇 |
1981年 | 18篇 |
1980年 | 27篇 |
1979年 | 35篇 |
1978年 | 17篇 |
1974年 | 13篇 |
1972年 | 13篇 |
1970年 | 14篇 |
1968年 | 12篇 |
排序方式: 共有3514条查询结果,搜索用时 15 毫秒
91.
Masao Omata Shuhei Nishiguchi Yoshiyuki Ueno Hitoshi Mochizuki Namiki Izumi Fusao Ikeda Hidenori Toyoda Osamu Yokosuka Kazushige Nirei Takuya Genda Takeji Umemura Tetsuo Takehara Naoya Sakamoto Yoichi Nishigaki Kunio Nakane Nobuo Toda Tatsuya Ide Mikio Yanase Keisuke Hino Bing Gao Kimberly L. Garrison Hadas Dvory‐Sobol Akinobu Ishizaki Masa Omote Diana Brainard Steven Knox William T. Symonds John G. McHutchison Hiroshi Yatsuhashi Masashi Mizokami 《Journal of viral hepatitis》2014,21(11):762-768
Genotype 2 hepatitis C virus (HCV) accounts for up to 30% of chronic HCV infections in Japan. The standard of care for patients with genotype 2 HCV – peginterferon and ribavirin for 24 weeks – is poorly tolerated, especially among older patients and those with advanced liver disease. We conducted a phase 3, open‐label study to assess the efficacy and safety of an all‐oral combination of the NS5B polymerase inhibitor sofosbuvir and ribavirin in patients with chronic genotype 2 HCV infection in Japan. We enrolled 90 treatment‐naïve and 63 previously treated patients at 20 sites in Japan. All patients received sofosbuvir 400 mg plus ribavirin (weight‐based dosing) for 12 weeks. The primary endpoint was sustained virologic response at 12 weeks after therapy (SVR12). Of the 153 patients enrolled and treated, 60% had HCV genotype 2a, 11% had cirrhosis, and 22% were over the aged 65 or older. Overall, 148 patients (97%) achieved SVR12. Of the 90 treatment‐naïve patients, 88 (98%) achieved SVR12, and of the 63 previously treated patients, 60 (95%) achieved SVR12. The rate of SVR12 was 94% in patients with cirrhosis and in those aged 65 and older. No patients discontinued study treatment due to adverse events. The most common adverse events were nasopharyngitis, anaemia and headache. Twelve weeks of sofosbuvir and ribavirin resulted in high rates of SVR12 in treatment‐naïve and previously treated patients with chronic genotype 2 HCV infection. The treatment was safe and well tolerated by patients, including the elderly and those with cirrhosis. 相似文献
92.
93.
94.
95.
Tomoko Noma Mai Kabayama Yasuyuki Gondo Saori Yasumoto Yukie Masui Ken Sugimoto Hiroshi Akasaka Kayo Godai Atsuko Higuchi Yuya Akagi Yoichi Takami Yasushi Takeya Koichi Yamamoto Kazunori Ikebe Yasumichi Arai Tatsuro Ishizaki Hiromi Rakugi Kei Kamide 《Geriatrics & Gerontology International》2020,20(7):720-726
96.
97.
Akihiro Yoshida Yoshinori Higuchi Masakazu Kondo Osamu Tabata Masamichi Ohishi 《Cranio : the journal of craniomandibular practice》2013,31(3):162-167
The purpose of this study was to determine the frequency and nature of temporomandibular joint (TMJ) involvement in rheumatoid arthritis (RA) patients with symptoms in this joint, and to investigate the relationship of symptoms to the C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and Steinbrocker stage. Clinical examination of the range of motion of the TMJ was performed in 218 RA patients. In addition, correlations between the maximal mouth opening and the severity of RA were studied. Restriction in opening the mouth (defined as ≤ 30 mm movement in the central incisor region from the fully occluded to maximally open positions) was observed in 12.8% of the RA patients (28/218). The CRP, ESR and Steinbrocker stage were all correlated with maximal opening (p < 0.05). There was a positive correlation between the severity of RA and the range of motion of the jaw. 相似文献
98.
99.
100.
Masaki Kaibori Shoji Kubo Hiroaki Nagano Michihiro Hayashi Seiji Haji Takuya Nakai Morihiko Ishizaki Kosuke Matsui Takahiro Uenishi Shigekazu Takemura Hiroshi Wada Shigeru Marubashi Koji Komeda Fumitoshi Hirokawa Yasuyuki Nakata Kazuhisa Uchiyama A-Hon Kwon 《World journal of surgery》2013,37(4):820-828