全文获取类型
收费全文 | 32315篇 |
免费 | 1495篇 |
国内免费 | 147篇 |
专业分类
耳鼻咽喉 | 340篇 |
儿科学 | 766篇 |
妇产科学 | 415篇 |
基础医学 | 4190篇 |
口腔科学 | 849篇 |
临床医学 | 2058篇 |
内科学 | 8578篇 |
皮肤病学 | 539篇 |
神经病学 | 2310篇 |
特种医学 | 1098篇 |
外科学 | 5671篇 |
综合类 | 153篇 |
一般理论 | 3篇 |
预防医学 | 965篇 |
眼科学 | 394篇 |
药学 | 2363篇 |
中国医学 | 130篇 |
肿瘤学 | 3135篇 |
出版年
2023年 | 172篇 |
2022年 | 304篇 |
2021年 | 527篇 |
2020年 | 285篇 |
2019年 | 400篇 |
2018年 | 497篇 |
2017年 | 434篇 |
2016年 | 472篇 |
2015年 | 485篇 |
2014年 | 665篇 |
2013年 | 822篇 |
2012年 | 1306篇 |
2011年 | 1390篇 |
2010年 | 840篇 |
2009年 | 740篇 |
2008年 | 1354篇 |
2007年 | 1514篇 |
2006年 | 1484篇 |
2005年 | 1608篇 |
2004年 | 1527篇 |
2003年 | 1541篇 |
2002年 | 1452篇 |
2001年 | 1189篇 |
2000年 | 1281篇 |
1999年 | 1121篇 |
1998年 | 459篇 |
1997年 | 326篇 |
1996年 | 334篇 |
1995年 | 302篇 |
1994年 | 270篇 |
1993年 | 290篇 |
1992年 | 789篇 |
1991年 | 721篇 |
1990年 | 688篇 |
1989年 | 745篇 |
1988年 | 662篇 |
1987年 | 615篇 |
1986年 | 565篇 |
1985年 | 533篇 |
1984年 | 352篇 |
1983年 | 295篇 |
1979年 | 265篇 |
1978年 | 191篇 |
1977年 | 162篇 |
1974年 | 157篇 |
1973年 | 167篇 |
1972年 | 167篇 |
1971年 | 157篇 |
1970年 | 157篇 |
1969年 | 146篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
91.
M Kobayashi A Koyama K Yamagata N Yamaguchi M Narita H Shigematsu 《Nihon Jinzo Gakkai shi》1992,34(1):47-56
The glomerular injuries in 129 cases of IgA nephropathy (IgA-N) were examined ultrastructurally with special reference to the glomerular basement membrane (GBM) deposits and capillary loop abnormalities, and the correlation between these findings and the clinicopathological data was analyzed. The following results were obtained. 1) The degree of daily excretion of urine protein (UP) and creatinine clearance (Ccr) revealed a significant correlation with the degree of mesangial hypercellularities and the frequency of segmental lesions. 2) All sites of GBM deposits, and discontinuity and/or splitting among the GBM abnormalities showed a significant relation to the severity of proliferation and segmental lesions. 3) The GBM deposits, discontinuity and splitting showed a significant relation to the degree of UP and Ccr. We speculate therefore that capillary loop deposits and/or capillary loop discontinuity and splitting could represent histological prognostic factors for an unfavorable outcome in IgA nephropathy. 相似文献
92.
93.
I Hisatome N Sasaki M Yamakawa M Kobayashi Y Tanaka H Kosaka A Yoshida H Kotake H Mashiba A Takeda 《Nephron》1992,61(2):196-199
Two patients with diabetes mellitus had persistent hypouricemia due to increased urate clearance; the degree of the apparent renal hypouricemia with uricosuria was quite mild. At the onset of diabetes, their serum urate levels were normal. Even after good diabetes control in both cases, hypouricemia continued. Based on the pharmacological evaluation in both patients, pyrazinamide administration could partially decrease urate clearance, however, suppression by pyrazinamide was less than in normal subjects, and probenecid increased urate clearance. These results suggest that the present cases had a renal abnormality affecting tubular presecretory reabsorption of urate, which might be due to diabetes mellitus. 相似文献
94.
K. Kobayashi N. Mukae Y. Matsunag M. Hotchi 《Burns : journal of the International Society for Burn Injuries》1990,16(6):414-417
This report gives details of an extensively burned patient who died of candidiasis. Retrospectively, by using the procedure of indirect immunoperoxidase staining, we measured the levels of antibody to candida in the stored patient's serum, collected from the time of admission to our hospital until death. Gradual increases in the antibody titres to candida were seen over the postburn period. The findings can be useful in diagnosing candidiasis. 相似文献
95.
96.
Masaki Shinoda Tsuyoshi Yamaguchi Yoshimi Tanaka Osamu Sato Sin Kobayashi Yutaka Suzuki 《Child's nervous system》1992,8(4):219-221
Single photon emission computerized tomography (SPECT) is now widely used as one of the tools in evaluating cerebral blood flow (CBF). The authors report the CBF changes in childhood hydrocephalus. Five pediatric cases studied by 123I-IM SPECT in children are presented. The authors counted radioactivities both in early and delayed images in each patient, and calculated the reabsorption ratio (RR). Two negative-RR cases and three positive-RR cases were found. All of the negative-RR patients had a poor prognosis, while all of the positive-RR patients had a favorable outcome. 相似文献
97.
Whether or not compromised host defense prior to surgical treatment is related to development of infection with methicillin-resistant staphylococcus aureus (MRSA) following major surgery was examined. Of 22 patients undergoing esophagectomy for cancer between 1989 and 1990, 5 were free from MRSA colonization and infection (group I) while 8 had MRSA colonization without infection (group II) and 9 had MRSA infection (group III). Levels of neutrophil cytocidal functions, complements, immunoglobulins and cell-mediated immunity were not significantly different among these three groups. The mean of anti pneumococcal polysaccharide (PPS)-IgG was significantly lower in group III than in group I (p < 0.05) and tended to be lower than in group II (P = 0.08). All infected patients showed a titer < 600 EU while all but one non-infected patient did so > 600 EU. Serum IgG2 levels positively correlated with anti-PSS IgG levels. Thus, we concluded that a preoperative evaluation of antibody response against polysaccharides and serum IgG2 levels can serve to predict development of MRSA-related infection following esophageal surgery. 相似文献
98.
A Yasuhara A Hori T Sugimoto S Iwase Y Kobayashi 《Electroencephalography and clinical neurophysiology》1987,67(6):584-587
Photo-evoked eyelid microvibration (PEMV) was recorded in neonates with intracranial hemorrhage in order to determine whether it serves as a useful indicator of clinical course and also prognosis. Although the latency of PEMV was prolonged or absent in the acute stage of ICH, it returned to a normal range in these subjects with the improvement of symptoms. Three infants whose PEMV were still prolonged in the convalescent stage developed mental retardation or cerebral palsy. PEMV may be a useful predictor of the prognosis of neonatal ICH and its prolongation may signal later neurological sequelae. 相似文献
99.
EDTA-extractable protein (EEP) is a major extrinsic protein of lens fiber membrane. The EEP of calf lens separated three major bands by SDS-PAGE, and the molecular weights of these major bands were 34 kilodalton (kd.), 33 kd. and 32 kd. Combination of EEP with F-actin and some kinds of phospholipid containing liposomes depends on Ca2+. In two-dimensional gel electrophoresis, some spots of the calf-EEP partially overlapped with spots of lipocortin, which is a substrate for epidermal growth factor receptor/kinase and an inhibitor of phospholipase A2. The 34 kd. protein of the EEP cross-reacted to the antibody prepared against lipocortin of pig's aorta: These results suggest the important function of EEP in lens. 相似文献
100.
Hiroshi Terasawa M.D. Kazuhisa Uchiyama M.D. Masaji Tani M.D. Manabu Kawai M.D. Takeshi Tsuji M.D. Katsuyoshi Tabuse M.D. Yasuhito Kobayashi M.D. Katsutoshi Taniguchi M.D. Hiroki Yamaue M.D. 《Journal of gastrointestinal surgery》2006,10(6):823-828
To determine the prognostic factors for patients with pathological T1 (pT1) carcinoma of the ampulla of Vater, 36 consecutive
patients with carcinoma of the ampulla of Vater who underwent surgery were retrospectively analyzed in terms of clinicopathological
features. The overall 5-year Kaplan-Meier survival in all patients was 50.2%, and the median survival of all patients was
64.0 months. Factors favorably influencing a long-term outcome were the absence of lymph node metastasis (P<0.0001), the absence of ulcer formation of the tumor (P=0.0062), and the absence of tumor invasion into the duodenum (P = 0.0025) and the pancreas (P=0.0098). In a multivariate analysis, lymph node metastasis was the only predictor of survival (P=0.0023). In the pT1 stage patients, 20% of the patients had lymph node metastasis, and their survival was statistically poor
compared to the pT1 patients without lymph node metastasis (P=0.017). As for survival after the operation, there was no significant difference between pancreatoduodenectomy and pylorus-preserving
pancreatoduodenectomy. 相似文献