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101.
Interleukin-5 is at 5q31 and is deleted in the 5q- syndrome 总被引:3,自引:0,他引:3
Sutherland GR; Baker E; Callen DF; Campbell HD; Young IG; Sanderson CJ; Garson OM; Lopez AF; Vadas MA 《Blood》1988,71(4):1150-1152
Human interleukin-5 (IL-5) is a selective eosinophilopoietic and eosinophil-activating growth hormone. By in situ hybridization this gene is mapped to chromosome 5q23.3 to 5q32. It is shown to be deleted in two patients with the 5q-syndrome and in one patient previously diagnosed with myelodysplasia whose condition had progressed to acute myeloblastic leukemia. The clustering of other genes involved in hematopoiesis (IL-3, granulocyte-macrophage colony-stimulating factor, feline sarcoma viral oncogene homolog, colony-stimulating factor 1) to the same region as IL-5 suggests a nonrandom localization and raises interesting questions concerning the evolution and regulation of these genes. 相似文献
102.
103.
104.
Percutaneous abdominal biopsy: cost-identification analysis 总被引:1,自引:0,他引:1
105.
Osseointegrated Implants for Prosthetic Rehabilitation after Treatment of Cancer of the Oral Cavity 总被引:1,自引:0,他引:1
The treatment of oral cancer usually involves extensive resection of the mandible, excision of oro-facial soft tissue and often radiotherapy. This causes difficulty in the subsequent oral rehabilitation. The present paper reports our experience with implant treatment of this patient group. The material comprises 38 implants in 12 patients. Four patients died during follow-up, two before loading the implants. The observation time after implantation was 7 to 47 months with a median of 14 months. Six of the patients had been subjected to preoperative radiation therapy. All 38 implants osseointegrated without complications. It is concluded that healing after implantation in irradiated mandibles can be achieved without hyperbaric oxygen. Provided certain guidelines are complied with i.e. careful surgical technique, use of antibiotics and prolonged period of healing prior to loading of the implants, a radiation dosage of up to 50 Gy appears to be of little significance. 相似文献
106.
Respiratory function was evaluated in 11 patients with prune-belly syndrome. Nine had evidence of gas trapping and six of restrictive lung disease. These abnormalities of lung function appear to be secondary to the musculoskeletal disorder associated with prune-belly syndrome rather than parenchymal lung disease. 相似文献
107.
In this experimental study we examined the effects of listening to relaxation-type music on self-reported anxiety and on selected physiologic indices of relaxation in patients with suspected myocardial infarction. Seventy-five patients were randomly assigned to one of two experimental groups, one listening to music and the other to "white noise," or to a control group. The State Anxiety Inventory was administered before and after each testing session, and blood pressure, heart rate, and digital skin temperature were measured at baseline and at 10-minute intervals for the 30-minute session. There was no significant difference among the three groups for state anxiety scores or physiologic parameters. Because no differences were found, analyses were conducted of the groups combined. Significant improvement in all of the physiologic parameters was found to have occurred. This finding reinforces the need for nurses to plan care that allows for uninterrupted rest for patients in the coronary care unit. 相似文献
108.
Mediastinal lymph node metastases from bronchogenic carcinoma: detection with MR imaging and CT 总被引:2,自引:0,他引:2
Poon PY; Bronskill MJ; Henkelman RM; Rideout DF; Shulman HS; Weisbrod GL; Steinhardt MI; Dunlap HJ; Ginsberg RJ; Feld R 《Radiology》1987,162(3):651-656
Magnetic resonance (MR) imaging and computed tomography (CT) were compared in a prospective study of 48 patients for the detection of metastatic mediastinal lymphadenopathy from bronchogenic carcinoma. The images were interpreted by three experienced radiologists using a five-point rating scale, enabling receiver operating characteristic (ROC) analysis. Imaging results were evaluated against "truth" data based on analysis of surgical specimens from mediastinoscopy and thoracotomy. All MR images were cardiac gated to reduce cardiac motion artifacts in the mediastinum. MR and CT both performed well, as indicated by similar areas under the ROC curves of 0.779 +/- 0.039 for MR imaging and 0.781 +/- 0.038 for CT scanning. No strong correlation between nodal size and metastatic involvement could be found for either MR or CT results. As long as nodal size remains the sole criterion in the detection of metastatic mediastinal lymphadenopathy, MR imaging is unlikely to enable better interpretations than CT scanning. 相似文献
109.
Pl Munk Dc Morris Dg Connell Jr Mayo Mj Lee DF Sallomi 《Journal of Medical Imaging and Radiation Oncology》1999,43(2):160-164
Liver biopsy is still most commonly done via the percutaneous route; however, increasingly, transvascular venous liver biopsy has been used in patients with bleeding disorders. Although the jugular route is now generally favoured, a transfemoral route can be a useful alternative technique when the jugular route is not available. We describe the transfemoral technique and outline a number of commonly encountered problems and complications and suggested methods of addressing them. 相似文献
110.
Martin H Voss David Chen Mahtab Marker A Ari Hakimi Chung-Han Lee James J Hsieh Jennifer J Knox Maurizio Voi Robert J Motzer 《British journal of cancer》2016,114(6):642-649