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131.
Wróblewska-Adamek I Wyszyńska M Kabała-Dzik A Mleczko W Picheta A 《Ginekologia polska》2007,78(4):303-306
OBJECTIVES: The aim of the study was to analyze the incidence of malignant cervical carcinomas found in the material from Histopathological Laboratory in Zawiercie District Hospital. MATERIAL AND METHODS: The examined materials included histopathological results concerning segments and scrapings from gynecological procedures and the results of the segments, collected during gynecological operations performed in the years 2000-2005, in which malignant neoplasms of uterine cervix had been diagnosed. The data concerning the neoplasms were analysed, taking into account the following parameters: the number of neoplasms found in relation to the total number of diagnostic procedures performed, patients' age, histological type of the neoplasm and the degree of clinical progression based on FIGO classification. RESULTS: In the examined material, there were 50 cases of cervical carcinomas, with the highest incidence in patients aged between 50-59. The most common morphological type was squamous carcinoma and the majority of cervical carcinomas was characterized by the I degrees of disease clinical progression--38 cases, also 4 preinvasive carcinomas were found and 8 cancers of the II degrees of progression, according to FIGO classification. CONCLUSION: A considerable decrease of cervical carcinomas incidence, observed in the study period and the number of neoplasms found in an early progression stage are the effect of conducted screening examinations, due to which precancerous conditions are diagnosed and treated. 相似文献
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134.
H. Assadeck M. Toudou Daouda É. Adehossi Omar Z. Mamadou F. Hassane Djibo D. Douma Maiga 《Revue neurologique》2019,175(4):261-268
Background
In sub-Saharan Africa (SSA), few studies have been reported on inflammatory demyelinating diseases of the central nervous system (CNS). Neuromyelitis optica spectrum disorders (NMOSD) seems to be the most frequent inflammatory demyelinating disease of CNS in sub-Saharan Africans or people of sub-Saharan African descent.Methods
We report the observations of seven patients from Niger diagnosed with inflammatory demyelinating diseases of CNS over a period of 21 years (1996–2017).Results
They were four women and three men aged 19 to 66 years (mean age: 37 years), with no known past medical history. Four patients were diagnosed with NMOSD (2 men and 2 women) and the three other patients with multiple sclerosis (MS, 2 women and 1 man). The three patients diagnosed with MS had the relapsing-remitting form. The cerebrospinal fluid study revealed the presence of oligoclonal bands in the three patients. Of the patients diagnosed with NMOSD, two patients negative anti-aquaporin 4 antibodies (anti-MOG antibodies not done), one of whom had bilateral optic neuritis (ON) with longitudinally extensive transverse myelitis (LETM) and the other unilateral ON with LETM. Two patients with MS were treated with interferon beta-1a and the third patient with azathioprine. The Expanded Disability Status Scale ranged from 1 to 2 in these three patients at the time of initiation of background treatment. Azathioprine was the treatment prescribed in the four patients with NMOSD. We did not find any case of acute disseminated encephalomyelitis.Conclusion
Our case series suggests the rarity of inflammatory demyelinating diseases of CNS in Niger, and NMOSD seems to be more frequent than MS. 相似文献135.
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137.
Samer E. Kaba Lauren A. Langford W.K. Alfred Yung Athanassios P. Kyritsis 《Journal of neuro-oncology》1996,30(1):55-60
Summary Ganglioglioma is an uncommon brain tumor with glial and neuronal cellular components and a somewhat benign course. We are presenting an unusual case of ganglioglioma with malignant transformation in both cellular components associated with an aggressive clinical course. An almost complete resolution of the recurrent progressing tumor was achieved after treatment with cis-retinoic acid (cRA) as a single agent. A possible differential effect of cRA on the neuronal component of the tumor is suggested. 相似文献
138.
The accessory olfactory bulb of the mouse was studied by current source-density analysis of field potentials to determine the laminar and temporal distribution of synaptic currents evoked by electrical stimulation of the vomeronasal organ. The one-dimensional current source-density analysis revealed two major spatially and temporally distinct inward membrane currents (sinks): one in the glomerular layer and the other in the external plexiform layer. The glomerular layer sink preceded the external plexiform layer sink by a mean of 5.5 ms. Local infusions of the broad-spectrum excitatory amino acid antagonist, kynurenate, into the accessory olfactory bulb blocked the external plexiform layer sink without an obvious effect on the glomerular layer sink. The selective non-N-methyl-D-aspartate receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dione produced a dose-dependent blockade of the external plexiform layer sink, whereas the selective N-methyl-D-aspartate receptor antagonist D-2-amino-5-phosphonovalerate was without effect. These results, taken together with the cytoarchitecture of the accessory olfactory bulb, suggest that the glomerular layer sink results mainly from synaptic excitation evoked in the glomerular dendritic branches of mitral cells by the vomeronasal afferent fibres and the external plexiform layer sink mainly from non-N-methyl-D-aspartate receptor-mediated synaptic excitation in the peripheral processes of granule cells via the mitral to granule cell dendrodendritic synapse. 相似文献
139.
The authors report the observation of a disease in fact the noma which one believed disappeared, it of it is nothing. This disease, summation of several factors, with frightening forecasts immediate and remote, must have before a whole preventive treatment by the improvement of the standard of living of the populations because its repair is so long, if difficult and so expensive that access will have well little there. 相似文献