The biochemical basis of nitroblue tetrazolium reduction in normal human and chronic granulomatous disease polymorphonuclear leukocytes

Normal human polymorphonuclear leukocytes (PMN) placed in anaerobic chambers reaching pO2's of less than 5 mm Hg fail to generate O2-, iodinate ingested particles, and stimulate glucose-1-14C oxidation through the hexose monophosphate shunt. The observation that anaerobic cells are incapable of generating O2- or reducing nitroblue tetrazolium (NBT) to formazan supports the idea that NBT reduction in phagocytizing PMN is due exclusively to oxygen-dependent O2- generating oxidase which is deficient in chronic granulomatous disease leukocytes, despite their hyperphagocytic capacity.     

Mobile screening mammography for the corporate customer.

While the concept of mobile imaging services is not new, mobile screening mammography has recently gained a great deal of attention, and several mobile breast screening programs are in operation throughout the United States. This article describes the development of a mobile breast screening program designed to attract corporations' employees as its primary source of participants. The design of the program, corporate concerns and operational issues are discussed as well as the findings of its first year of operation.     

The radiographic detection of foreign bodies

While many foreign bodies are easily demonstrated on routine radiographs, others are of low radiopacity and may necessitate the use of special techniques or equipment for detection. Since routine radiography is usually the initial method for the investigation of a suspected foreign body, it is beneficial for the technologist to be familiar with several more effective techniques. The purpose of this paper is to acquaint the technologist with the application of these techniques in foreign body detection.