全文获取类型
收费全文 | 2004篇 |
免费 | 84篇 |
专业分类
耳鼻咽喉 | 24篇 |
儿科学 | 83篇 |
妇产科学 | 77篇 |
基础医学 | 159篇 |
口腔科学 | 54篇 |
临床医学 | 310篇 |
内科学 | 473篇 |
皮肤病学 | 90篇 |
神经病学 | 101篇 |
特种医学 | 26篇 |
外科学 | 279篇 |
综合类 | 82篇 |
一般理论 | 9篇 |
预防医学 | 142篇 |
眼科学 | 18篇 |
药学 | 134篇 |
肿瘤学 | 27篇 |
出版年
2016年 | 9篇 |
2015年 | 25篇 |
2014年 | 29篇 |
2013年 | 33篇 |
2012年 | 12篇 |
2011年 | 10篇 |
2010年 | 50篇 |
2009年 | 61篇 |
2008年 | 9篇 |
2007年 | 11篇 |
2005年 | 9篇 |
2003年 | 13篇 |
2001年 | 18篇 |
2000年 | 14篇 |
1999年 | 33篇 |
1998年 | 37篇 |
1997年 | 81篇 |
1996年 | 58篇 |
1995年 | 39篇 |
1994年 | 57篇 |
1993年 | 45篇 |
1992年 | 38篇 |
1991年 | 37篇 |
1990年 | 45篇 |
1989年 | 34篇 |
1988年 | 45篇 |
1987年 | 33篇 |
1986年 | 28篇 |
1985年 | 15篇 |
1984年 | 21篇 |
1983年 | 18篇 |
1982年 | 28篇 |
1981年 | 23篇 |
1980年 | 23篇 |
1979年 | 26篇 |
1978年 | 15篇 |
1977年 | 18篇 |
1976年 | 16篇 |
1975年 | 13篇 |
1972年 | 11篇 |
1971年 | 9篇 |
1963年 | 14篇 |
1959年 | 72篇 |
1958年 | 124篇 |
1957年 | 126篇 |
1956年 | 134篇 |
1955年 | 115篇 |
1954年 | 136篇 |
1949年 | 42篇 |
1948年 | 44篇 |
排序方式: 共有2088条查询结果,搜索用时 734 毫秒
91.
92.
STEPHAN ZELLERHOFF M.D. RUDIN PISTULLI M.D. GEROLD MÖNNIG M.D. MARTIN HINTERSEER M.D. BRITT‐MARIA BECKMANN M.D. JULIA KÖBE M.D. GERHARD STEINBECK M.D. F.E.S.C. STEFAN KÄÄB M.D. WILHELM HAVERKAMP M.D. F.E.S.C. LARISSA FABRITZ RAINER GRADAUS M.D. F.E.S.C. ERIC SCHULZE‐BAHR M.D. DIRK BÖCKER M.D. PAULUS KIRCHHOF M.D. F.E.S.C. F.H.R.S. 《Journal of cardiovascular electrophysiology》2009,20(4):401-407
Background: The long-QT syndromes (LQTS) are inherited electrical cardiomyopathies characterized by prolonged ventricular repolarization and ventricular arrhythmias. Several genetic reports have associated defects in LQTS-causing genes with atrial fibrillation (AF). We therefore studied whether atrial arrhythmias occur in patients with LQTS under daily-life conditions.
Methods: We systematically assessed atrial arrhythmias in LQTS patients and matched controls using implanted defibrillators or pacemakers as monitors of atrial rhythm in a nested case-control study. Twenty-one LQTS patients (3 male; 39 ± 18 years old; 18 on β blocker, ICD therapy duration 6.3 ± 2.7 years; 4 LQT1, 6 LQT2, 2 LQT3) were matched to 21 control subjects (13 male; 50 ± 19 years old; 3 on β blocker; pacemaker therapy duration 8.5 ± 5.5 years; 19 higher-degree AV block, 2 others). LQTS patients were identified by a systematic search of the LQTS patient databases in Münster and Munich.
Results: One-third (7 of 21) of the LQTS patients developed self-terminating atrial arrhythmias (atrial cycle lengths <250 ms). Only one control patient developed a single episode of postoperative AF (P < 0.05 vs LQTS).
Conclusions: LQTS patients at high risk for ventricular arrhythmias may develop short-lasting atrial arrhythmias under daily-life conditions, suggesting that prolonged atrial repolarization may contribute to the initiation of AF. 相似文献
Methods: We systematically assessed atrial arrhythmias in LQTS patients and matched controls using implanted defibrillators or pacemakers as monitors of atrial rhythm in a nested case-control study. Twenty-one LQTS patients (3 male; 39 ± 18 years old; 18 on β blocker, ICD therapy duration 6.3 ± 2.7 years; 4 LQT1, 6 LQT2, 2 LQT3) were matched to 21 control subjects (13 male; 50 ± 19 years old; 3 on β blocker; pacemaker therapy duration 8.5 ± 5.5 years; 19 higher-degree AV block, 2 others). LQTS patients were identified by a systematic search of the LQTS patient databases in Münster and Munich.
Results: One-third (7 of 21) of the LQTS patients developed self-terminating atrial arrhythmias (atrial cycle lengths <250 ms). Only one control patient developed a single episode of postoperative AF (P < 0.05 vs LQTS).
Conclusions: LQTS patients at high risk for ventricular arrhythmias may develop short-lasting atrial arrhythmias under daily-life conditions, suggesting that prolonged atrial repolarization may contribute to the initiation of AF. 相似文献
93.
94.
Hepatitis C viral load, genotype and histological severity in patients with bleeding disorders 总被引:1,自引:0,他引:1
We report the relationship between hepatitis C virus (HCV) titre, liver histology and HCV genotype in patients with bleeding disorders. One hundred and thirty-two RIBA-2-positive patients, including 56 who were also HIV positive, were identified at our centre. Fifty of these patients, including nine who were HIV infected, underwent percutaneous liver biopsy. Liver histology was assessed using a modified histological activity index (HAI). Qualitative serum HCV PCR was positive in 87 (87%) of the 101 patients tested including 43 of 50 biopsied patients. HCV RNA titres, measured by quantitative PCR, were significantly higher in HIV-positive patients compared with HIV-negative patients (P < 0.05) but were not related to HAI, mean factor concentrate usage, duration of HCV infection or HCV genotype. There was no relationship between HCV genotype and HAI. Qualitative HCV PCR was positive in 30 of 43 liver biopsies tested. Biopsy PCR-positive and -negative cohorts were not distinguished by HAI or serum HCV titre. We conclude that although serum HCV PCR is useful in confirming the presence of HCV infection in patients with bleeding disorders, little meaningful information concerning the severity of the disease can be obtained from serum HCV quantification. 相似文献
95.
MARTIN JP 《Brain : a journal of neurology》1945,68(3):167-187
96.
D. M. MARTIN 《International endodontic journal》1991,24(4):204-211
The dental profession within the UK is currently reviewing the desirability of recognition of practice-based specialties and the establishment of specialist registers in various disciplines, including endodontics. In order to merit consideration for specialty status, in any discipline there must be an increase in the level of theoretical knowledge, and in the range and complexity of clinical procedures beyond the basic level of training. There must be an identified public need extending beyond the provisions of the general dental services for the particular skills of the practice-based specialist, who would also complement the consultant services, which have a limited capacity to provide the level of treatment demanded. Acceptance of the principle of specialist practice implies a belief that this will enhance the development of the profession, improve academic and clinical standards and provide a higher-quality and more widely available service to the public. The case for the specialist endodontist is argued, as is the importance of establishing appropriate academic and clinical training programmes to equip individuals with the requisite knowledge and skills. Academic institutions must develop imaginative and innovative courses to provide such education within the profession. 相似文献
97.
98.
BO SÖGAARD-PEDERSEN HANS BOYE MARTIN EBBE MATTHIESSEN 《European journal of oral sciences》1990,98(2):89-95
Abstract – Human permanent teeth were examined in the scanning electron microscope after demineralization and exposure to preparative procedures based on hydrogen peroxide, trypsin, and EDTA. These substances removed the inorganic material, the cellular structures, the homogeneous connective tissue ground substance, and interfibrillar matrix. The remaining tissue components comprised a network of distinct collagen fibers whose organization was related to the type of tissue in which these were incorporated. A similar or identical method has not been developed or applied to teeth previously. Dentin and predentin comprised a compact mass of fibers which basically were parallel to the continuously growing interior surface of the predentin, or arranged at an acute angle to this plane. Collagen fibers in the pulp were numerous, but lacked any particular orientation in most areas. Interodontoblastic fibers crossed the odontoblastic zone at a right angle to the pulp chamber wall and mingled with collagen fibers in predentin. When previously published findings of ours are taken into account, it is possible to conclude that other factors than the organization of the collagen fibers are responsible for the stainability of these fibers in predentin and in interglobular dentin with silver methenamine, and that aldehyde groups on collagen fibers in predentin may be actively and directly involved in the mineralization of the dentin. 相似文献
99.
100.
The porcine bronchial artery: surgical and angiographic anatomy 总被引:2,自引:0,他引:2
JOHN GADE MARTIN A. NORGAARD CLAUS B. ANDERSEN GÖSTA PETTERSSON ULRIK G. SVENDSEN PETER S. OLSEN 《Journal of anatomy》1999,194(2):241-247
The pig is often used in experimental studies on the significance of bronchial artery circulation, but the anatomy of this artery is only poorly described. The purpose of this study was to improve the anatomical basis for experimental studies on the porcine bronchial artery circulation. The origin of the artery from the aorta is described in 32 pigs. Heart–lung blocks were perfused with saline and removed in 16 pigs, and the broncho-oesophageal orifice was identified and cannulated. In these 16 specimens the intrapulmonary ramification was studied by angiography, and the extrapulmonary distribution and supply area by injection of Evans Blue. The broncho-oesophageal artery originated from the aorta as a single trunk in 91%. Angiography showed that each principal bronchus was accompanied by 2 bronchial artery branches far into the lung parenchyma. The central branching pattern of the artery between the aorta and the principal bronchi was divided into 3 subtypes. Evans Blue showed communication with the whole mediastinum. The anatomical relations are described. It is concluded that the broncho-oesophageal artery divides to follow each bronchus with 2 bronchial branches. A nomenclature for these branches is suggested. The pig anatomy is suited for experimental investigations on the bronchial circulation. 相似文献