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41.
HANS KOTTKAMP M.D. XU CHEN M.D. GERHARD HINDRICKS M.D. STEPHAN WILLEMS M.D. MARTIN BORGGREFE M.D. GÜNTER BREITHARDT M.D. 《Journal of cardiovascular electrophysiology》1994,5(3):268-273
Idiopathic Left Ventricular Tachycardia. Introduction: Idiopathic left ventricular tachycardia with a QRS pattern of right bundle branch block and left-axis deviation constitutes a rare but electrophysiologically distinct arrhythmia entity. The underlying mechanism of this tachycardia, however, is still a matter of controversy. This report describes findings in a 42-year-old man who underwent successful radiofrequency catheter ablation of idiopathic left ventricular tachycardia.
Methods and Results: On electrophysiologic study, the tachycardia was reproducibly induced and terminated with double ventricular extrastimuli. Intravenous verapamil terminated the tachycardia whereas adenosine did not. Detailed left ventricular catheter mapping during sinus rhythm revealed a fragmented delayed potential at the mid-apical region of the inferior site near the posterior fascicle of the left bundle branch. At the same site, continuous electrical activity throughout the entire cardiac cycle was recorded during ventricular tachycardia. Repeated spontaneous termination of this continuous electrical activity in late diastole was followed immediately by termination of the tachycardia. Single application of radiofrequency current for 20 seconds at this site completely abolished inducibility of the tachycardia. After catheter ablation, at the identical site of preablation recording of the fractionated potential during sinus rhythm, no fragmented delayed activity could be recorded. There was no complication from the ablation procedure.
Conclusion: The preablation recordings of fragmented delayed potentials during sinus rhythm and continuous diastolic electrical activity during tachycardia, together with ablation characteristics and previously reported electrophysiologic properties of this arrhythmia, may further support microreentry as the underlying mechanism in idiopathic left ventricular tachycardia. 相似文献
Methods and Results: On electrophysiologic study, the tachycardia was reproducibly induced and terminated with double ventricular extrastimuli. Intravenous verapamil terminated the tachycardia whereas adenosine did not. Detailed left ventricular catheter mapping during sinus rhythm revealed a fragmented delayed potential at the mid-apical region of the inferior site near the posterior fascicle of the left bundle branch. At the same site, continuous electrical activity throughout the entire cardiac cycle was recorded during ventricular tachycardia. Repeated spontaneous termination of this continuous electrical activity in late diastole was followed immediately by termination of the tachycardia. Single application of radiofrequency current for 20 seconds at this site completely abolished inducibility of the tachycardia. After catheter ablation, at the identical site of preablation recording of the fractionated potential during sinus rhythm, no fragmented delayed activity could be recorded. There was no complication from the ablation procedure.
Conclusion: The preablation recordings of fragmented delayed potentials during sinus rhythm and continuous diastolic electrical activity during tachycardia, together with ablation characteristics and previously reported electrophysiologic properties of this arrhythmia, may further support microreentry as the underlying mechanism in idiopathic left ventricular tachycardia. 相似文献
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MARTIN L. LESSER 《Statistics in medicine》1996,15(20):2127-2133
This paper seeks to help biostatisticians develop realistic budgets for their involvement in research projects. The approach is to list categories of expenses and associated questions about the types and levels of projected costs that the budget planner needs to consider. I subdivide the expense categories into smaller subcomponents that should provide for better planning. I also propose an algorithm for determining hourly rates. 相似文献
47.
MARTIN GABA 《British Journal of Learning Disabilities》1989,17(3):128-129
Mental Handicap has occasionally published items of this nature in the past and the Editor would welcome such contributions for consideration for future issues. Readers who would care to write in this vein, or who can persuade any consumers with whom they are in contact to do so, should contact the Editorial Office (Tel. (0562) 824933) for guidelines. 相似文献
48.
ANTHONY A. CALDAMONE SHYH-CHYAN CHEN JACK S. ELDER MICHAEL L. RITCHEY DAVID A. DIAMOND MARTIN A. KOYLE 《The Journal of urology》1999,162(4):1430-1432
PURPOSE: Congenital anterior urethrocutaneous fistula is a rare anomaly that may present in an isolated fashion or in association with other penile abnormalities, such as chordee or hypospadias. There have been 18 cases of congenital anterior urethrocutaneous fistula reported in the literature. We present 14 additional cases of congenital anterior urethrocutaneous fistula. MATERIALS AND METHODS: We treated 14 patients with congenital anterior urethrocutaneous fistula, of whom 9 were uncircumcised at presentation. Two patients had evidence of chordee and 4 had distal hypospadias. RESULTS: The type of repair was determined by the anatomical variations of this anomaly. All cases were corrected electively by various techniques based on the degree of the defect, including primary closure via a Thiersch-Duplay urethroplasty, pedicle flap urethroplasty, hinged flap urethroplasty and interpositioned island pedicle tube or onlay urethroplasty. CONCLUSIONS: To our knowledge the embryological events that cause anterior urethrocutaneous fistula are unclear but they likely result from a defective urethral plate or an abnormality of the infolding of the urethral groove. Surgical technique must be individualized to fit the defect. While there has been considerable skepticism regarding the existence of congenital urethrocutaneous fistula, the fact that 9 of our 14 patients were uncircumcised confirms the congenital nature of this lesion. 相似文献
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Ventricular Arrhythmia Burden in Patients With Heart Failure and Cardiac Resynchronization Devices: The Importance of Renal Function 下载免费PDF全文
GIRISH GANESHA BABU M.D. M.R.C.P. MATTHEW WEBBER M.R.C.P. M.B.Ch.B. RUI PROVIDENCIA M.D. SANJEEV KUMAR M.D. M.R.C.P. Ph.D. AERAKONDAL GOPALAMURUGAN M.D. M.R.C.P. C.C.D.S. DOMINIC P. ROGERS M.A. M.D. M.R.C.P. HOLLY LOUISE DAW B.Sc. SYED AHSAN M.D. M.R.C.P. ANTHONY CHOW M.D. F.R.C.P. MARTIN LOWE Ph.D. F.R.C.P. EDWARD ROWLAND M.D. F.R.C.P. F.E.S.C. F.A.C.C. PIER LAMBIASE Ph.D. F.R.C.P. F.H.R.S. OLIVER R. SEGAL M.D. F.R.C.P. F.H.R.S. 《Journal of cardiovascular electrophysiology》2016,27(11):1328-1336