全文获取类型
| 收费全文 | 2587623篇 |
| 免费 | 185058篇 |
| 国内免费 | 7569篇 |
专业分类
| 耳鼻咽喉 | 34281篇 |
| 儿科学 | 85297篇 |
| 妇产科学 | 71575篇 |
| 基础医学 | 363632篇 |
| 口腔科学 | 69669篇 |
| 临床医学 | 234514篇 |
| 内科学 | 515531篇 |
| 皮肤病学 | 62466篇 |
| 神经病学 | 213445篇 |
| 特种医学 | 99877篇 |
| 外国民族医学 | 736篇 |
| 外科学 | 386450篇 |
| 综合类 | 50397篇 |
| 现状与发展 | 5篇 |
| 一般理论 | 968篇 |
| 预防医学 | 196171篇 |
| 眼科学 | 56669篇 |
| 药学 | 188006篇 |
| 8篇 | |
| 中国医学 | 5331篇 |
| 肿瘤学 | 145222篇 |
出版年
| 2021年 | 19981篇 |
| 2019年 | 20619篇 |
| 2018年 | 29283篇 |
| 2017年 | 22591篇 |
| 2016年 | 26223篇 |
| 2015年 | 29500篇 |
| 2014年 | 40438篇 |
| 2013年 | 60422篇 |
| 2012年 | 80218篇 |
| 2011年 | 84481篇 |
| 2010年 | 51001篇 |
| 2009年 | 49141篇 |
| 2008年 | 79017篇 |
| 2007年 | 83828篇 |
| 2006年 | 85559篇 |
| 2005年 | 81723篇 |
| 2004年 | 78718篇 |
| 2003年 | 76037篇 |
| 2002年 | 73328篇 |
| 2001年 | 128406篇 |
| 2000年 | 131329篇 |
| 1999年 | 110501篇 |
| 1998年 | 31255篇 |
| 1997年 | 27929篇 |
| 1996年 | 28225篇 |
| 1995年 | 27390篇 |
| 1994年 | 25076篇 |
| 1993年 | 23431篇 |
| 1992年 | 85166篇 |
| 1991年 | 81566篇 |
| 1990年 | 78793篇 |
| 1989年 | 76071篇 |
| 1988年 | 69481篇 |
| 1987年 | 68006篇 |
| 1986年 | 63552篇 |
| 1985年 | 60518篇 |
| 1984年 | 44951篇 |
| 1983年 | 37950篇 |
| 1982年 | 22462篇 |
| 1981年 | 19989篇 |
| 1979年 | 38969篇 |
| 1978年 | 27442篇 |
| 1977年 | 23258篇 |
| 1976年 | 21500篇 |
| 1975年 | 22821篇 |
| 1974年 | 26789篇 |
| 1973年 | 25383篇 |
| 1972年 | 23753篇 |
| 1971年 | 21958篇 |
| 1970年 | 20186篇 |
排序方式： 共有10000条查询结果，搜索用时 11 毫秒
21.
22.
23.
24.
25.
26.
Daniel J. Snyder Thomas R. Kroshus Aakash Keswani Evan B. Garden Karl M. Koenig Kevin J. Bozic David S. Jevsevar Jashvant Poeran Calin S. Moucha 《The Journal of arthroplasty》2019,34(4):613-618
Background
Nursing Home Compare (NHC) ratings, created and maintained by Medicare, are used by both hospitals and consumers to aid in the skilled nursing facility (SNF) selection process. To date, no studies have linked NHC ratings to actual episode-based outcomes. The purpose of this study was to evaluate whether NHC ratings are valid predictors of 90-day complications, readmission, and bundle costs for patients discharged to an SNF after primary total joint arthroplasty (TJA).Methods
All SNF-discharged primary TJA cases in 2017 at a multihospital academic health system were queried. Demographic, psychosocial, and clinical variables were manually extracted from the health record. Medicare NHC ratings were then collected for each SNF. For patients in the Medicare bundle, postacute and total bundle cost was extracted from claims.Results
Four hundred eighty-eight patients were discharged to a total of 105 unique SNFs. In multivariate analysis, overall NHC rating was not predictive of 90-day readmission/major complications, >75th percentile postacute cost, or 90-day bundle cost exceeding the target price. SNF health inspection and quality measure ratings were also not predictive of 90-day readmission/major complications or bundle performance. A higher SNF staffing rating was independently associated with a decreased odds for >75th percentile 90-day postacute spend (odds ratio, 0.58; P = .01) and a 90-day bundle cost exceeding the target price (odds ratio = 0.69; P = .02) but was similarly not predictive of 90-day readmission/complications.Conclusion
Results of our study suggest that Medicare's NHC tool is not a useful predictor of 90-day costs, complications, or readmissions for SNFs within our health system. 相似文献27.
Joseph M. Northey Kate L. Pumpa Clare Quinlan Ashley Ikin Kellie Toohey Disa J. Smee Ben Rattray 《Journal of Science and Medicine in Sport》2019,22(5):580-585
Objectives
The current study investigated the effects of two exercise interventions on cognitive function amongst breast cancer survivors.Design
Pilot randomised-controlled trial.Methods
Seventeen female cancer survivors (mean: 62.9 ± 7.8 years) were randomised into three groups: high-intensity interval training (HIIT, n = 6); moderate-intensity continuous training (MOD, n = 5); or wait-list control (CON, n = 6). The HIIT and MOD groups exercised on a cycle ergometer 3 days/week for 12-weeks. Primary outcomes were cognitive function assessments utilising CogState. Secondary outcomes were resting middle cerebral artery blood flow velocity, cerebrovascular reactivity and aerobic fitness (VO2peak). Data were analysed with General Linear Mixed Models and Cohen’s d effect sizes were calculated.Results
All 17 participants who were randomised were available for follow-up analysis and adherence was similar for HIIT and MOD (78.7 ± 13.2% vs 79.4 ± 12.0%; p = 0.93). Although there were no significant differences in the cognitive and cerebrovascular outcomes, HIIT produced moderate to large positive effects in comparison to MOD and CON for outcomes including episodic memory, working memory, executive function, cerebral blood flow and cerebrovascular reactivity. HIIT significantly increased VO2peak by 19.3% (d = 1.28) and MOD had a non-significant 5.6% (d = 0.72) increase, compared to CON which had a 2.6% decrease.Conclusions
This study provides preliminary evidence that HIIT may be an effective exercise intervention to improve cognitive performance, cerebrovascular function and aerobic fitness in breast cancer survivors. Considering the sample size is small, these results should be confirmed through larger clinical trials. 相似文献28.
Saisanjana Kalagara Adam E.M. Eltorai J. Mason DePasse Alan H. Daniels 《The spine journal》2019,19(1):182-185
BACKGROUND
Online physician rating websites are increasingly used by patients to evaluate their doctors. The purpose of this investigation was to evaluate factors associated with better spine surgeon ratings.METHODS
Orthopedic spine surgeons were randomly selected from the North American Spine Society directory utilizing a random number generator. Surgeon profiles on three physician rating websites, namely, www.HealthGrades.com, www.Vitals.com, and www.RateMDs.com, were analyzed to gather qualitative and quantitative data on patients’ perceptions of the surgeons. Independent variables from the websites were analyzed in relation to overall physician or patient satisfaction rating. Comments were coded by subject into following three categories: professional competence, bedside manner, and practice characteristics.RESULTS
A total of 250 surgeons were evaluated, and 92% (n=230) of these doctors had at least one rating among the three websites. The surgeons with a higher average rating had significantly better trust (p<.01), scheduling (p<.01), staff (p<.01), helpfulness (p<.01), and punctuality (p<.01) scores but significantly less experience (p<.05). A linear regression model for the average rating of each surgeon (R2 value=0.754) yielded only following three significant variables: trustworthiness (p<.01), experience match (p<.05), and the average number of negative comments on surgeon's professional competence (p<.05). Trustworthiness (β=0.749) was the strongest predictor variable of physician rating, followed by the number of negative professional competence comments (β=?0.132) and experience match (β=?0.112).CONCLUSIONS
This investigation assessed spine surgeon online patient ratings and categorized factors that patients associate with quality care. Trustworthiness was the most significant predictor of positive ratings, whereas ease of scheduling, quality of staff, helpfulness, and punctuality were also associated with higher patient ratings. Understanding what patients value may help optimize care of spine surgery patients. 相似文献29.
Ludger Klimek Annette Sperl Sven Becker Ralph Mösges Peter Valentin Tomazic 《Expert opinion on pharmacotherapy》2019,20(1):83-89
Introduction: Allergic rhinitis is a common condition with increasing prevalence and is associated with several comorbid disorders such as bronchial asthma and atopic dermatitis. If allergen avoidance is not possible, allergen-specific immunotherapy is the only causal treatment option.
Areas covered: This review focuses on current treatments and the future outlook for allergic rhinitis. Pharmacotherapy includes mast cell stabilizers, antihistamines, glucocorticosteroids (GCSs), leukotriene receptor antagonists, and nasal decongestants. Nasal GCSs are currently regarded as the most effective treatment and are considered first-line therapy together with non-sedating antihistamines. The new formulation MP29-02 combines the nasal GCS fluticasone propionate with azelastine in one single spray and has achieved greater improvements than those under monotherapy with modern GCSs or antihistamines. Furthermore, this review discusses allergen immunotherapy alone and in combination with modern monoclonal antibodies.
Expert opinion: Despite the variety of medications for allergic rhinitis, ranging from general symptomatic agents like GCSs or decongestants, to more specific ones like histamine receptor or leukotriene blockers, to causal therapy like immunotherapy, many patients still experience treatment failures or unsatisfactory results. The ultimate goal may be to endotype every downstream pathway separately in order to offer patients individualized, targeted therapy with specific antibodies against the respective pathway. 相似文献
30.