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991.
Salvatore S Hauser B Devreker T Vieira MC Luini C Arrigo S Nespoli L Vandenplas Y 《Nutrition (Burbank, Los Angeles County, Calif.)》2007,23(6):498-506
OBJECTIVE: Several studies in recent decades have assessed the effects of different probiotics in acute gastroenteritis, showing that specific strains of Lactobacilli (mainly Lactobacillus casei GG) and Saccharomyces boulardii may exert some beneficial therapeutic actions, mainly when used in rotavirus gastroenteritis, at a high dose, and in the early phase. The mechanisms of action of probiotics are not completely elucidated but seem to involve a complex interaction among epithelial, molecular, metabolic, and immune responses. Data on the prevention of community-acquired, nosocomial, and travelers' diarrhea are currently conflicting. Because each micro-organism has different properties, an accurate selection of the strain, dose, and patient should be cautiously considered. METHODS AND RESULTS: Several reports from developing countries have demonstrated that supplements of zinc also provide significant reduction in stool output and duration, persistency, and severity of diarrhea. In view of the published data and of the different actions of zinc (such as improvement of the immune status, intestinal permeability, epithelial and enzymatic function, and electrolyte transport), the use of zinc as adjunctive therapy to oral rehydration solution has the potential to improve the management of diarrhea and decrease complications in children worldwide. In contrast to probiotics, which most trials in the developed world have used, there has been no trial with zinc performed in developed countries. CONCLUSION: Data on the effect of a combined administration of zinc and probiotics in acute gastroenteritis are urgently needed. 相似文献
992.
BACKGROUND: Data from cross-sectional studies revealed that gingival recession commonly occurred in subjects with a good standard of oral hygiene, but very little has been reported about longitudinal changes in the presence and extent of gingival recession in a similar sample of the population. The aim of this study was to follow up on the evolution of gingival recession at buccal tooth surfaces in a student population attending the fifth year at Bologna University Dental School who had been examined in a study 5 years earlier. METHODS: The clinical examination involved assessment of the number of buccal surfaces with plaque and buccal gingival recession. Information about toothbrushing habits (brushing technique and frequency and toothbrush bristle stiffness) was collected in an interview. RESULTS: The number of subjects with at least one recession and the total number of recessions had increased significantly. Comparing data from the baseline and the present study, no significant differences were observed for toothbrush type and frequency of toothbrushing, whereas the use of correct brushing techniques increased to 87% of the subjects. CONCLUSION: The percentage of affected sites increased with the level of oral hygiene education, and this increase developed despite a reduction in the frequency of dangerous toothbrushing habits. 相似文献
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995.
Impaired clearance of microemboli and cerebrovascular symptoms during carotid stenting procedures 总被引:4,自引:0,他引:4
Orlandi G Fanucchi S Gallerini S Sonnoli C Cosottini M Puglioli M Sartucci F Murri L 《Archives of neurology》2005,62(8):1208-1211
BACKGROUND: Transcranial Doppler monitoring shows a high prevalence of microemboli during carotid artery stenting (CAS); however, the occurrence of cerebrovascular symptoms (CVSs) does not seem to be related to the microembolic load. OBJECTIVE: To evaluate embolic and hemodynamic transcranial Doppler monitoring findings and their relationships with the occurrence of procedural CVSs. Patients Fifty-four patients who had carotid stenosis of more than 70% underwent a total of 57 CAS procedures during transcranial Doppler monitoring of mean blood flow velocity and microembolic signals in the middle cerebral artery. The occurrence of transient ischemic attack, transient monocular blindness, and stroke during the CAS procedure was considered CVSs. RESULTS: Nine (15.8%) of the 57 patients had CVSs during the procedure (ie, 6 patients with transient ischemic attack, 1 with transient monocular blindness, 1 with a minor stroke, and 1 with a major stroke). The mean blood flow velocity median values were statistically significantly lower (P < .001) in the group of 9 patients with CVSs (36 cm/s; interquartile range, 32.3-38.5) compared with the 48 without CVSs (48 cm/s; interquartile range, 41.5-52). The median number of isolated microembolic signals was similar in the 2 groups (72; interquartile range, 66-81 vs 75; interquartile range, 67-83.5). The median number of microembolic signal showers (clusters of too many signals to be counted separately in one cardiac cycle) presented a nonsignificant prevalence in the patients with CVSs (9; interquartile range, 7.5-11.2) compared with the ones without CVSs (8.2; interquartile range, 7-9). CONCLUSION: The low flow velocity in the middle cerebral artery may impair the clearance of the microembolic load and should be considered a precursor of CVSs during the CAS procedure. 相似文献
996.
Giacomo Pata Claudio Casella Ernesto Di Betta Luigi Grazioli Bruno Salerni 《World journal of surgery》2009,33(8):1611-1617
Background In hemodynamically stable patients after blunt pancreatic trauma, the main pancreatic duct (MPD) disruption (American Association
for the Surgery of Trauma [AAST] grade III-IV-V lesions) is usually treated surgically or by endoscopic stent placement, whereas
injuries without duct involvement (grade I-II) are liable to medical treatment. To date, no evidence has been reported regarding
nonoperative management (NoM) of grade III injuries. We aimed to evaluate the safety of extending medical management to include
cases of distal MPD involvement (grade III).
Patients and methods Data were collected on patients admitted after blunt pancreatic trauma between January 1999 and December 2007. Patients exhibiting
hemodynamic instability or hollow organ perforations were excluded from this study, as they were surgically managed. In all
remaining cases NoM was attempted. Antibiotic prophylaxis and early total enteral nutrition were routinely adopted. Grade
III patients received octreotide during hospitalization and for 6 months after discharge.
Results Eleven patients (2 with grade I injury, 3 with grade II injury, and 6 with grade III injury, all diagnosed by contrast-enhanced
helical CT) were included. Nonsurgical management was carried out in all of these patients. Among grade III patients, one
developed a peripancreatic abscess; another, a pancreatic fistula. Both were successfully treated nonoperatively. The average
length of hospital stay was similar in grade I-II and grade III patients. After a median follow-up of 57 months no mortality
or pancreatic sequelae had occurred.
Conclusions Under the aforementioned conditions, an attempt to extend NoM to include patients with AAST-grade III lesions can be justified. However, such a strategy demands
continuous patient monitoring, because should the case worsen, surgery might become necessary. 相似文献
997.
Olivier Facy Vito De Blasi Martine Goergen Luca Arru Luigi De Magistris Juan-Santiago Azagra 《Surgical endoscopy》2013,27(10):3841-3845
Background
Intestinal anastomosis is a complex procedure during laparoscopy, mainly due to the difficulties knotting the sutures. Unidirectional barbed sutures have been proposed to simplify wall and mesentery closure, but the results for intestinal anastomosis are not clear. This study aimed to establish the feasibility and the safety of laparoscopic intestinal anastomosis using barbed suture.Methods
Between June 2011 and May 2012, 15-cm-long unidirectional absorbable barbed sutures (V-Loc; Covidien, Mansfield, MA, USA) were used for all laparoscopic intestinal anastomoses: one suture for closure of intestinal openings after mechanical anastomoses and two sutures for hand-sewn anastomoses.Results
Over a 1-year period, 201 consecutive patients required 220 laparoscopic anastomoses for gastrojejunostomy (n = 177; 172 during Roux-en-Y gastric bypass and 5 after gastrectomy), ileocolostomy (n = 15), colocolostomy (n = 1), esophagojejunostomy (n = 5), and jejunojejunostomy (n = 22; 4 after small bowel resection and 18 during gastric bypass or gastrectomy). Senior and training surgeons performed 209 closures of intestinal openings and 11 hand-sewn anastomoses. There was no conversion to usual sutures. One fistula occurred in an esophagojejunostomy and was managed conservatively. One self-limited anastomotic bleeding occurred, and no anastomotic stenosis occurred during 6 months of follow-up evaluation.Conclusions
The use of knotless barbed suture for laparoscopic intestinal anastomosis is safe and reproducible. 相似文献998.
Gardner Cameron L. Pavel-Dinu Mara Dobbs Kerry Bosticardo Marita Reardon Paul K. Lack Justin DeRavin Suk See Le Kent Bello Ezekiel Pala Francesca Delmonte Ottavia M. Malech Harry Montel-Hagen Amelie Crooks Gay Acuto Oreste Porteus Matthew H. Notarangelo Luigi D. 《Journal of clinical immunology》2021,41(5):863-863
Journal of Clinical Immunology - A Correction to this paper has been published: https://doi.org/10.1007/s10875-021-01030-6 相似文献
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