全文获取类型
收费全文 | 710篇 |
免费 | 57篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 32篇 |
妇产科学 | 4篇 |
基础医学 | 58篇 |
口腔科学 | 32篇 |
临床医学 | 61篇 |
内科学 | 175篇 |
皮肤病学 | 48篇 |
神经病学 | 17篇 |
特种医学 | 131篇 |
外科学 | 38篇 |
综合类 | 80篇 |
预防医学 | 26篇 |
药学 | 40篇 |
2篇 | |
肿瘤学 | 28篇 |
出版年
2023年 | 4篇 |
2021年 | 13篇 |
2020年 | 3篇 |
2019年 | 10篇 |
2018年 | 17篇 |
2017年 | 10篇 |
2016年 | 12篇 |
2015年 | 15篇 |
2014年 | 19篇 |
2013年 | 20篇 |
2012年 | 17篇 |
2011年 | 11篇 |
2010年 | 21篇 |
2009年 | 28篇 |
2008年 | 18篇 |
2007年 | 14篇 |
2006年 | 35篇 |
2005年 | 7篇 |
2004年 | 11篇 |
2003年 | 15篇 |
2002年 | 8篇 |
2001年 | 9篇 |
2000年 | 6篇 |
1999年 | 7篇 |
1998年 | 30篇 |
1997年 | 50篇 |
1996年 | 46篇 |
1995年 | 34篇 |
1994年 | 33篇 |
1993年 | 36篇 |
1992年 | 18篇 |
1991年 | 8篇 |
1990年 | 13篇 |
1989年 | 13篇 |
1988年 | 17篇 |
1987年 | 9篇 |
1986年 | 6篇 |
1985年 | 10篇 |
1984年 | 10篇 |
1983年 | 11篇 |
1982年 | 16篇 |
1981年 | 14篇 |
1980年 | 8篇 |
1979年 | 6篇 |
1978年 | 7篇 |
1977年 | 6篇 |
1976年 | 17篇 |
1975年 | 11篇 |
1973年 | 3篇 |
1971年 | 3篇 |
排序方式: 共有774条查询结果,搜索用时 0 毫秒
701.
The efficacy and safety of betamethsone dipropionate 0.05% with salicylic acid 2% scalp lotion was evaluated in 60 patients with moderate to severe scalp psoriasis. Out of 120 patients with scalp psoriasis 60 patients received PUVASOL alone and 60 patients received PUVASOL alongwith lotion 0.05% betamethasone dipropionate with 2% salicylic acid scalp application for 3 weeks. The erythema, induration, scales and pruritus steadily improved in patients throughout the 3 weeks treatment course with betamethasone dipropionate with salicylic acid scalp application. At the end of therapy 84.3% of those patients receiving PUVASOL and betamethasone dipropionate-salicylic acid combination had 75% improvement of their scalp psoriasis versus 34.9% of those patients using PUVASOL alone. Complete clearing of the scalp was seen in 35% patients receiving therapy with topical betamethasone-salicylic acid and 11.6% with PUVASOL alone. Local side effects were primarily burning and stinging in 5 (83%) cases treated with topical betamethasone salicylic acid scalp application and 1 (1.6%) receiving PUVASOL alone. Combined therapy with PUVASOL and topical betamethasone dispropionate 0.05% with salicyclic acid 2% application appears to be safe and an effective treatment for scalp psoriasis.KEY WORDS: Betamethasone dipropionate, PUVASOL, Photochemotherapy, Scalp psoriasis 相似文献
702.
Rafael O Alvim Silvia RS Freitas Noely E Ferreira Paulo CJL Santos Roberto S Cunha José G Mill José E Krieger Alexandre C Pereira 《Lipids in health and disease》2010,9(1):128
Background
Cardiovascular diseases (CVD) are the main cause of death and disability in developed countries. In most cases, the progress of CVD is influenced by environmental factors and multifactorial inheritance. The purpose of this study was to investigate the association between APOE genotypes, cardiovascular risk factors, and a non-invasive measure of arterial stiffness in the Brazilian population. 相似文献703.
Diana Menya Nicholas Kigen Margaret Oduor Stephen Karuru Maina Fatma Some David Chumba Paul Ayuo Odipo Osano Daniel RS Middleton Joachim Schüz Valerie A McCormack 《International journal of cancer. Journal international du cancer》2019,144(3):459-469
Squamous cell esophageal cancer is common throughout East Africa, but its etiology is poorly understood. We investigated the contribution of alcohol consumption to esophageal cancer in Kenya, based on a hospital-based case–control study conducted from 08/2013 to 03/2018 in Eldoret, western Kenya. Cases had an endoscopy-confirmed esophageal tumor whose histology did not rule out squamous cell carcinoma. Age and gender frequency-matched controls were recruited from hospital visitors/patients without digestive diseases. Logistic regression was used to calculate odds ratios (ORs) and their 95% confidence intervals (CI) adjusting for tobacco (type, intensity) and 6 other potential confounders. A total of 422 cases (65% male, mean at diagnosis 60 (SD 14) years) and 414 controls were included. ORs for ever-drinking were stronger in ever-tobacco users (9.0, 95% CI: 3.4, 23.8, with few tobacco users who were never drinkers) than in never-tobacco users (2.6, 95% CI: 1.6, 4.1). Risk increased linearly with number of drinks: OR for >6 compared to >0 to ≤2 drinks/day were 5.2 (2.4, 11.4) in ever-tobacco users and 2.1 (0.7, 4.4) in never-tobacco users. Although most ethanol came from low ethanol alcohols (busaa or beer), for the same ethanol intake, if a greater proportion came from the moonshine chang'aa, it was associated with a specific additional risk. The population attributable fraction for >2 drinks per day was 48% overall and highest in male tobacco users. Alcohol consumption, particularly of busaa and chang'aa, contributes to half of the esophageal cancer burden in western Kenya. 相似文献
704.
Assessing and addressing cognitive impairment in bipolar disorder: the International Society for Bipolar Disorders Targeting Cognition Task Force recommendations for clinicians 下载免费PDF全文
705.
Hillary B. Nguyen Emily Lipner Liisa Hantsoo Sara L. Kornfield Robert D. Davies C. Neill Epperson 《Current psychiatry reports》2018,20(12):110
Purpose of Review
With increasing numbers of transgender and gender non-binary individuals presenting for care, knowing how to elucidate the mental health and cognitive outcomes of gender-affirming hormone therapy (GAHT) is necessary. This article reviews the present literature covering GAHT effects on mood, behavioral health, and cognition in these individuals and offers research priorities to address knowledge gaps.Recent Findings
Although there are some conflicting data, GAHT overwhelmingly seems to have positive psychological effects in both adolescents and adults. Research tends to support that GAHT reduces symptoms of anxiety and depression, lowers perceived and social distress, and improves quality of life and self-esteem in both male-to-female and female-to-male transgender individuals.Summary
Clinically, prescribing GAHT can help with gender dysphoria-related mental distress. Thus, timely hormonal intervention represents a crucial tool for improving behavioral wellness in transgender individuals, though effects on cognitive processes fundamental for daily living are unknown. Future research should prioritize better understanding of how GAHT may affect executive functioning.706.
707.
708.
709.
Onychomycosis is a fungal infection of the nail unit, and is the most common of the nail disorders. Current therapies for onychomycosis have less than ideal efficacy and have the potential for adverse effects. As previous studies have shown that nonthermal plasma inhibits the in vitro growth of Trichophyton rubrum, we conducted a pilot study on 19 participants with toenail onychomycosis. The primary endpoint was safety of the device, and secondary outcome measures were clinical efficacy and mycological cure. Patient satisfaction was measured using questionnaires at the completion of the study. All but one patient met the primary endpoint of safety and there were no long‐term sequelae. The overall clinical cure was 53.8% and the mycological cure was 15.4%. The majority of patients were satisfied with the treatment. Our conclusions are that nonthermal plasma is a safe treatment and may have a beneficial effect on toenail onychomycosis. 相似文献
710.