全文获取类型
收费全文 | 43669篇 |
免费 | 2751篇 |
国内免费 | 134篇 |
专业分类
耳鼻咽喉 | 367篇 |
儿科学 | 1376篇 |
妇产科学 | 1209篇 |
基础医学 | 5461篇 |
口腔科学 | 588篇 |
临床医学 | 6976篇 |
内科学 | 7559篇 |
皮肤病学 | 541篇 |
神经病学 | 4382篇 |
特种医学 | 963篇 |
外国民族医学 | 1篇 |
外科学 | 4766篇 |
综合类 | 464篇 |
现状与发展 | 1篇 |
一般理论 | 58篇 |
预防医学 | 5306篇 |
眼科学 | 802篇 |
药学 | 2777篇 |
中国医学 | 47篇 |
肿瘤学 | 2910篇 |
出版年
2023年 | 216篇 |
2022年 | 375篇 |
2021年 | 710篇 |
2020年 | 481篇 |
2019年 | 761篇 |
2018年 | 956篇 |
2017年 | 686篇 |
2016年 | 766篇 |
2015年 | 869篇 |
2014年 | 1261篇 |
2013年 | 2073篇 |
2012年 | 2832篇 |
2011年 | 3052篇 |
2010年 | 1625篇 |
2009年 | 1465篇 |
2008年 | 2788篇 |
2007年 | 3007篇 |
2006年 | 2875篇 |
2005年 | 2855篇 |
2004年 | 2659篇 |
2003年 | 2527篇 |
2002年 | 2442篇 |
2001年 | 390篇 |
2000年 | 322篇 |
1999年 | 437篇 |
1998年 | 518篇 |
1997年 | 450篇 |
1996年 | 351篇 |
1995年 | 379篇 |
1994年 | 314篇 |
1993年 | 297篇 |
1992年 | 259篇 |
1991年 | 262篇 |
1990年 | 231篇 |
1989年 | 192篇 |
1988年 | 207篇 |
1987年 | 183篇 |
1986年 | 196篇 |
1985年 | 218篇 |
1984年 | 266篇 |
1983年 | 236篇 |
1982年 | 273篇 |
1981年 | 291篇 |
1980年 | 271篇 |
1979年 | 175篇 |
1978年 | 169篇 |
1977年 | 161篇 |
1976年 | 140篇 |
1975年 | 149篇 |
1974年 | 142篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
ERP evidence of impaired central nervous system function in virally suppressed HIV patients on antiretroviral therapy. 总被引:2,自引:0,他引:2
Linda L Chao Joselyn A Lindgren Derek L Flenniken Michael W Weiner 《Clinical neurophysiology》2004,115(7):1583-1591
OBJECTIVE: To examine the effects of human immunodeficiency virus (HIV) on central nervous system (CNS) function in patients receiving antiretroviral therapy (ART) who have suppressed viral loads. METHODS: Event-related brain potentials (ERPs) were recorded from 15 virally suppressed HIV patients and 15 age-, sex-, and education-matched controls while they performed a 3-stimulus auditory oddball task. The amplitude and latency of the P3a, P3b, and early auditory components were examined in HIV patients and controls. RESULTS: Virally suppressed HIV patients on ART were more depressed than controls, as determined by the Beck Depression Inventory (BDI). After controlling for the effects of depression, HIV patients had smaller P2, P3a, and P3b amplitudes and longer P3a and P3b latency than control subjects. BDI scores correlated positively with N1 latency in HIV patients and negatively with P3b amplitude in all subjects. CONCLUSIONS: These electrophysiological results suggest that, even in the absence of detectable levels of HIV in the peripheral blood, viral replication persists in the CNS and continues to cause disease in HIV patients on ART. 相似文献
72.
Anesthesia safety for endoscopic laryngeal laser surgery has been a major limiting factor for laser applications in the larynx and the hypopharynx. Several anesthesia techniques have been proposed and each technique appears to have its own limitations. This paper will deal with the distinct advantages offered by the malleable copper tube which is used for delivery of the open Venturi system anesthesia for endoscopic laser surgery. A retrospective study of 100 patients who have undergone this modality of anesthesia at our institution will be presented. Our conclusion from this study shows clearly the superiority of the copper tube over the conventional aluminium-foil-wrapped endotracheal tube in safety and the exposure of the larynx during surgery. 相似文献
73.
Anucha Apisarnthanarak Pattarachai Kiratisin Kanokporn Thongphubeth Chananart Yuakyen Linda M Mundy 《Infection control and hospital epidemiology》2007,28(5):637-639
We describe a pseudo-outbreak of Acinetobacter lwoffii infection that was recognized early. The pseudo-outbreak involved 16 patients and occurred 3.5 months after the GNS-506 Vitek automated system was introduced in the microbiology laboratory. Prompt confirmation of incomplete use of the automated system's algorithm as the point source of the misidentified A. lwoffii clinical isolates averted a full outbreak investigation and excess use of infection control resources. 相似文献
74.
75.
HYPOTHESIS: Irrigation of the mastoid with a quinolone antibiotic-steroid solution may mitigate hearing loss caused by iatrogenic semicircular canal injury in the presence of Pseudomonas aeruginosa (PA) otitis media (OM). BACKGROUND: Studies have shown the cochlea to be more vulnerable to semicircular canal transection (SCT)-related hearing loss in the presence of PA OM. Prophylactic systemic antibiotics and steroids may decrease this hearing loss, but SCT is usually not planned. The aim of this study was to determine if irrigation with ciprofloxacin-dexamethasone (cipro-dex) could improve hearing outcomes following SCT in PA OM. METHODS: PA OM was induced in 28 animals. After three to five days, unilateral SCT was performed in each animal, with sham SCT on the contralateral ear. At surgery, half of the animals (n = 14) underwent irrigation of the both mastoid bullae with cipro-dex; the second group of animals (n = 14) underwent irrigation of the bullae with sterile saline. Auditory thresholds were obtained immediately prior to SCT and 7-10 days after SCT. RESULTS: SCT ears treated with cipro-dex showed a mean click threshold improvement of 4.6 dB from pre-transection to 7-10 days post-transection, whereas thresholds in the SCT ears treated with saline worsened by 7.5 dB (p = 0.15). CONCLUSION: Irrigation of the guinea pig bulla with cipro-dex following SCT in the setting of PA OM appears safe and may yield beneficial effects on hearing. 相似文献
76.
77.
78.
79.
Bibhuti B Das Linda B Pauliks Ole A Knudson Scott Kirby Kak-Chen Chan Lilliam Valdes-Cruz Raul O Cayre 《Journal of the American Society of Echocardiography》2005,18(3):231-236
We identified 18 patients with double-orifice mitral valve (DOMV) and intact atrioventricular (AV) septum out of 40,179 echocardiographic studies performed between 1997 and 2002 at Children's Hospital, Denver, CO. In this study we describe (1) the anatomic characteristics of the DOMV in the absence of AV septal defect, (2) the function of the mitral valve by spectral and color Doppler flow mapping, and (3) associated lesions. The topographic location of the orifices in the leaflets suggests possible embryologic mechanisms of DOMV. In this series, DOMV was most commonly associated with left-sided obstructive lesions (in 39% of patients). Spectral and color Doppler interrogation demonstrated a normal flow profile in most cases; only 2 patients had significant mitral regurgitation or stenosis. Therefore, due to the uncertain natural history of this lesion and the potential need for endocarditis prophylaxis, careful imaging of the mitral valve is recommended, particularly in the presence of left-sided obstructive lesions. 相似文献
80.