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排序方式: 共有2410条查询结果,搜索用时 31 毫秒
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Annie Hardison-Moody Lillian MacNell Sinikka Elliott Sarah Bowen 《Journal of the Academy of Nutrition and Dietetics》2018,118(10):1886-1894.e1
Background
This study focuses on the cultural, social, and economic factors that shape infant feeding practices among low-income mothers.Objective
The objective was to understand factors that inhibit or facilitate breastfeeding practices of low-income mothers, including how they are linked to broader social, cultural, and economic processes.Design
In-depth qualitative interviews were conducted with women about their feeding practices and food environments, including their experiences with breastfeeding and formula feeding.Participants
The sample was comprised of 98 low-income mothers with at least one child between 2 and 9 years old at the time of interview.Results
Sixteen mothers (16.7%) breastfed for 6 months, and six (6.3%) were still breastfeeding at 12 months. Only 11 mothers (11.5%) exclusively breastfed for 6 months. Women reported several factors influencing infant feeding: interactions with medical providers, work environments, shared living spaces and family supports, and concerns about supply and production.Conclusions
This research highlights the complex interplay of economic and social barriers that shape how and what low-income women feed their infants. The study contributes to a better understanding of the social, cultural, and economic constraints faced by women in poverty. To improve breastfeeding rates among low-income women, it is important to examine the impacts of poverty and food insecurity on infant feeding practices. 相似文献75.
Beesdo-Baum Katja Knappe Susanne Einsle Franziska Knothe Lisa Wieder Gesine Venz John Rummel-Kluge Christine Heinz Ines Koburger Nicole Schouler-Ocak Meryam Wilbertz Theresia Unger Hans-Peter Walter Ulrich Hein Joachim Hegerl Ulrich Lieb Roselind Pfennig Andrea Schmitt Jochen Hoyer Jürgen Wittchen Hans-Ulrich Bergmann Antje 《Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz》2018,61(1):52-64
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz - Hausärzte sind als Primärversorger für Patienten mit depressiven Störungen entscheidende Weichensteller... 相似文献
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Double-chimaerism after transplantation of two human leucocyte antigen mismatched,unrelated cord blood units 总被引:5,自引:0,他引:5
De Lima M St John LS Wieder ED Lee MS McMannis J Karandish S Giralt S Beran M Couriel D Korbling M Bibawi S Champlin R Komanduri KV 《British journal of haematology》2002,119(3):773-776
The small number of progenitor cells is the major limitation to the use of umbilical cord blood (UCB) for the transplantation of adults. We tested the hypothesis that two units transplanted simultaneously could each contribute to haematopoietic reconstitution. A patient with advanced acute lymphocytic leukaemia received a mismatched, unrelated UCB transplant using units from two donors after conditioning. The recipient achieved a complete remission without graft-versus-host disease. Double chimaerism was documented in several leucocyte subpopulations; both units contributed to haematopoiesis until relapse. Triple chimaerism was present from relapse until death due to leukaemia. This approach may potentially improve UCB transplantation outcome for adults lacking a histocompatible donor. 相似文献
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Menzel T; Rahman Z; Calleja E; White K; Wilson EL; Wieder R; Gabrilove J 《Blood》1996,87(3):1056-1063
Chronic lymphocytic leukemia (CLL) is characterized by delayed senescence and slow accumulation of monoclonal, small lymphocytes. Basic fibroblast growth factor (bFGF) is a pleiotropic cytokine that plays a role in hematopoiesis and apoptosis. Elevated bFGF levels have been detected in urine from patients with a variety of neoplastic diseases including various leukemias; however, the cellular source of the bFGF has not been determined. In this study, the intracellular bFGF level in lymphocytes of 36 patients with B-CLL and 15 normal donors was determined using an enzyme-linked immunoassay. In cells derived from patients with high-risk disease, the median level of intracellular bFGF was 381.5 pg/2 x 10(5) cells, compared with a median of 90.5 pg/2 x 10(5) cells in patients with intermediate disease. In patients with low- risk disease, the median bFGF level was 4.9 pg/2 x 10(5) cells, and in normal controls, it was 6.0 pg/2 x 10(5) cells. The difference in the bFGF levels was significant for the comparison between low- and intermediate-risk (P = .00119), low- and high-risk (P < .0001), and intermediate- and high-risk disease (P = .0001). Immunofluorescent stains of peripheral blood mononuclear cells confirmed CLL lymphocytes as a cellular source of bFGF. To evaluate the potential contribution of elevated intracellular bFGF levels to the phenotype of CLL cells, leukemic cells were cultured in vitro with an apoptotic stimulus (fludarabine). CLL cells with high intracellular levels of bFGF appeared to be more resistant to fludarabine treatment. The addition of bFGF to fludarabine-treated CLL cells resulted in a delay of apoptosis and prolonged survival. These data suggest that bFGF may contribute to the resistance of CLL cells to an apoptotic stimulus. 相似文献