Indications of antibiotic prophylaxis in dental practice- Review

Antibiotics are frequently used in dental practice. Clinical and bacteriological epidemiological factors determine the indications of antibiotics in dentistry. Antibiotics are used in addition to appropriate treatment to aid the host defences in the elimination of remaining bacteria. It is indicated when there is evidence of clinical sign involvement and spread of infection. Antibiotics are prescribed in dental practice for treating odontoge nic infections, non-odontogenic infections, as prophylaxis against focal and local infection. Special care needs to be addressed to patients with organ transplants, poorly controlled diabetes and pregnancy. Antibiotics should be used only as an adjunct to dental treatment and never alone as the first line of care. The present paper reviews the indications of antibiotics in dental practice.     

Effects of the Interaction of the ANKK1/DRD2 TaqIA and HTR2C Cys23Ser Polymorphisms on Approach Motivation in Schizophrenia Patients and Healthy People

Neuroscience and Behavioral Physiology - Objective. To assess the association of the DRD2 gene and its interaction with the HTR2C gene with the characteristics of the hedonistic and activatory...     

Association of -717A>G Polymorphism in the C-Reactive Protein Gene (CRP) with Schizotypal Personality Traits

Bulletin of Experimental Biology and Medicine - Associations between schizotypal traits and genes coding for inflammation markers (Creactive protein and TNF-α) were studied in 222 healthy men...     

Ortner's syndrome: - case series and literature review

More than a century ago, Ortner described a case of cardiovocal syndrome wherein he attributed a case of left vocal fold immobility to compression of the recurrent laryngeal nerve by a dilated left atrium in a patient with mitral valve stenosis. Since then, the term Ortner's syndrome has come to encompass any nonmalignant, cardiac, intrathoracic process that results in embarrassment of either recurrent laryngeal nerve-usually by stretching, pulling, or compression; and causes vocal fold paralysis. Not surprisingly, the left recurrent laryngeal nerve, with its longer course around the aortic arch, is more frequently involved than the right nerve, which passes around the subclavian artery.ObjectivesTo discuss the pathogenesis of hoarseness resulting from cardiovascular disorders involving the recurrent laryngeal nerve along with the findings of literature review.Materials and methodsThis paper reports a series of four cases of Ortner's syndrome occurring due to different causes.DesignCase study.ResultOrtner's syndrome could be a cause of hoarseness of voice in patients with cardiovascular diseases.ConclusionAlthough hoarseness of voice is frequently encountered in the Otolaryngology outpatient department, cardiovascular- related hoarseness is an unusual presentation. Indirect laryngoscopy should be routinely performed in all cases of heart disease.     

Effects of the Interaction of Variants of the Serotonin Transporter and Brain-Derived Neurotrophic Factor on Platelet Serotonin Levels in Stroke Patients

Polymorphisms in two genes, i.e., the serotonin transporter and brain-derived neurotrophic factor, were studied in 47 patients with ischemic stroke. Platelet serotonin content was found to differ in carriers of different genetic variants. The lowest serotonin contents were found in patients with the LL*ValVal variant and the highest in those with the LL genotype and genotypes containing at least one copy of the Met allele. Genetic variants were not found to have any modulatory influences on the relationship between platelet serotonin content during the acute phase of stroke and the development of affective or anxiety disorders by the patients.