Tongue somatosensory-evoked potentials in microvascular decompression treated trigeminal neuralgia

Somatosensory-evoked potentials of the tongue (tSSEP) provide useful information about trigeminal-afferent pathway. The aim of this study was to evaluate tSSEP in trigeminal neuralgia (TN) treatment with microvascular decompression. Two patients with trigeminal neuralgia refractory to conservative treatment underwent microvascular decompression of the trigeminal nerve. tSSEP was performed a month prior to surgery and in the month after the surgery in both patients. Pain frequency and tSSEP were analyzed before and after surgery. In both patients, a complete resolution of pain occurred. In patient 1, tSSEP latencies became shorter than before surgery and wave N1 appeared. The intensity of stimulation necessary to reach the threshold was 4 mA before the surgery and 1 mA after the surgery. A complete recovery of tSSEP after the operation was achieved in patient 2. The results of present study demonstrate potential value of tSSEP in pre-surgery evaluation and post-surgery follow-up of TN patients.     

Unrecognized hemangiopericytoma of posterior cervical region with intracranial extension

Hemangiopericytoma of the posterior cervical space and occipital bone is an uncommon lesion which should be considered in the differential diagnosis of a lumpy and highly vascular lesion of the posterior cervical space. We report the case of a 47-year-old woman who experienced sudden and painful occipital and posterior cervical swelling. She underwent a blind biopsy which was complicated by profuse bleeding. The palpable lesion was not properly diagnosed preoperatively, and the endocranial extension of the lesion was overlooked by her surgeon who performed a blind biopsy without adequate diagnostic imaging who inadvertently invaded the posterior cranial fossa during biopsy. We would like to emphasize the need for appropriate non-invasive diagnostic investigations before any biopsy of head and neck lesions that may extend deeply.     

A preliminary study of the comparative effects of olanzapine and fluphenazine on cognition in schizophrenic patients

The aim of the study was to compare the effect of olanzapine versus fluphenazine treatment on cognitive functioning. Eighteen schizophrenic outpatients, aged 25 - 61 (average 37 years), all meeting DSM-IV diagnostic criteria for schizophrenia, were included in the study. They were randomly assigned to 22 weeks of either olanzapine or fluphenazine treatment. Certain subscales of the Wechsler Adult Intelligence Scale, the Stroop Neuropsychological Screening Test and the Wisconsin Card Sorting Test were performed. Olanzapine treatment proved to have a beneficial effect on digit-symbol performance and some aspects of executive function. In comparison to the fluphenazine treatment, the olanzapine treatment only showed a beneficial effect in increased percentage of conceptual level responses. Although the results are preliminary, they could implicate that the benefit of olanzapine treatment is primarily related to certain aspects of executive function, i.e. frontal lobe functioning. Copyright 2000 John Wiley & Sons, Ltd.     

Accuracy of the oscillometric method to measure blood pressure in children

OBJECTIVE: The aim of this study is to analyze the substitution of the standard auscultatory method by the oscillometric blood pressure monitor, independently of the validity of the intraarterial blood pressure measurement. The accuracy of the automatic oscillometric monitor was compared to the auscultatory mercury manometer blood pressure measurement in apparently healthy school age children. METHODS: A device able to perform 3 simultaneous readings are used: one reading by the monitor and the others by two "blind" observers. We studied 72 school age children with the following characteristics: mean age 9.5 (6.1-16.1) and 39 males (54.2%). RESULTS: The difference for the systolic and diastolic blood pressure obtained by the monitor was in average + 6.2 mmHg and + 10.0 mmHg, respectively, when compared to the observer's readings. There was neither a good correlation nor a good agreement between the two observers and the monitor in the blood pressure determination. CONCLUSIONS: We concluded that the substitution of the standard auscultatory method for the non-invasive oscillometric method to measure blood pressure in school age children can not be generally recommended.