全文获取类型
收费全文 | 117篇 |
免费 | 8篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 11篇 |
妇产科学 | 1篇 |
基础医学 | 11篇 |
口腔科学 | 3篇 |
临床医学 | 34篇 |
内科学 | 26篇 |
皮肤病学 | 3篇 |
神经病学 | 3篇 |
外科学 | 14篇 |
预防医学 | 6篇 |
药学 | 11篇 |
肿瘤学 | 1篇 |
出版年
2022年 | 1篇 |
2021年 | 2篇 |
2017年 | 2篇 |
2016年 | 3篇 |
2015年 | 3篇 |
2014年 | 2篇 |
2013年 | 3篇 |
2012年 | 1篇 |
2010年 | 4篇 |
2009年 | 5篇 |
2008年 | 1篇 |
2007年 | 2篇 |
2005年 | 1篇 |
2003年 | 1篇 |
2001年 | 2篇 |
2000年 | 1篇 |
1999年 | 3篇 |
1998年 | 2篇 |
1997年 | 8篇 |
1996年 | 6篇 |
1995年 | 6篇 |
1994年 | 5篇 |
1993年 | 4篇 |
1992年 | 4篇 |
1991年 | 3篇 |
1990年 | 4篇 |
1989年 | 1篇 |
1988年 | 3篇 |
1987年 | 4篇 |
1986年 | 1篇 |
1984年 | 1篇 |
1979年 | 4篇 |
1978年 | 1篇 |
1975年 | 2篇 |
1973年 | 1篇 |
1969年 | 1篇 |
1959年 | 1篇 |
1958年 | 3篇 |
1957年 | 5篇 |
1956年 | 9篇 |
1955年 | 7篇 |
1954年 | 1篇 |
1953年 | 1篇 |
排序方式: 共有125条查询结果,搜索用时 15 毫秒
121.
122.
JOHN W. PERICH MARIA RUZZENE LORENZO A. PINNA ERIC C. REYNOLDS 《Chemical biology & drug design》1994,43(1):39-46
A general synthetic method for the efficient preparation of Tyr(P) -containing peptides is described by the use of Fmoc-Tyr(PO31Bu2) -OH in Fmoc/solid-phase synthesis followed by simultaneous cleavage of the peptide from the resin and peptide deprotection by acidolytic treatment. The applicability of this approach is demonstrated by the synthesis of H-Ser-Ser-Ser-Tyr(P) -Tyr(P) -OH.TFA and the synthesis of the phosphorylated forms of the two physiological peptides, angiotensin II and neurotensin 8–13. In addition, the three phosphorylated peptides were used as substrates in the study of the local specificity determinants of T-cell protein tyrosine phosphatase. In a competition assay using 32P-radiolabeled [Tyr(P)]4-angiotensin II, both un-labeled synthetic [Tyr(P)]4-angiotensin II and Ser-Ser-Ser-Tyr(P) -Tyr(P) reduced the release of 32P and indicated that they efficiently competed as substrates for the phosphatase. Conversely, [Tyr(P)]4-neurotensin 8–13 was ineffective as a competitive substrate and indicated that this particular Tyr(P) -containing peptide sequence was not recognized by the enzyme. The marked difference in the recognition of Asp-Arg-Val-Tyr(P) -Ile-His-Pro-Phe and Arg-Arg-Pro-Tyr(P) -Ile-Leu is consistent with the presence of an acidic residue in the -3 position relative to the Tyr(P) residue. 相似文献
123.
Cerebrospinal Fluid Dynamics in Megalencephaly 总被引:1,自引:1,他引:0
MICHAEL J. BRESNAN ANTONIO V. LORENZO 《Developmental medicine and child neurology》1975,17(S35):51-57
124.
MARIA A. PIZZICHETTA MD IGNAZIO STANGANELLI MD RICCARDO BONO MD H. PETER SOYER MD SERENA MAGI SCD VINCENZO CANZONIERI MD GIUSEPPE LANZANOVA MD GIORGIO ANNESSI MD CESARE MASSONE MD LORENZO CERRONI MD RENATO TALAMINI SCD ON BEHALF OF THE ITALIAN MELANOMA INTERGROUP 《Dermatologic surgery》2007,33(1):91-99
BACKGROUND: The dermoscopic diagnosis of cutaneous melanoma (CM) may be difficult because some CM lack specific dermoscopic features for melanoma diagnosis. OBJECTIVE: To evaluate whether a diagnosis of CM could be achieved using the classic dermoscopic melanoma-specific criteria, we conducted a retrospective multicenter study of 508 CM samples. METHODS: All the dermoscopic images were analyzed to identify the dermoscopic criteria found in dermoscopically difficult melanomas (DDM) and to examine the possible relation of dermoscopic diagnosis with respect to the difficulty of the dermoscopic diagnosis and the melanoma thickness. RESULTS: A significant percentage of melanomas, 89 of 508 (17.5%), were DDM. The criteria leading to a significant increased risk of DDM were presence of streaks [odds ratio (OR), 2.26; 95% confidence interval (CI), 1.15-4.47), absence or presence of regular pigmentation (OR, 3.41; 95% CI, 1.70-6.85), absence of a blue-whitish veil (OR, 4.04; 95% CI, 2.33-6.99), absence of regression structures (OR, 4.31; 95% CI, 2.42-7.66), and the presence of hypopigmentation (OR, 2.61; 95% CI, 1.49-4.58). CONCLUSION: A significant number of melanomas defy even dermoscopic diagnosis. Only a meticulous comparative and interactive process based on an assessment of all the individual's other nevi ("ugly ducking" sign) and a knowledge about recent changes can lead to the recognition of DDM. 相似文献
125.
Miniaturized Implantable Loop Recorder in Small Patients: An Effective Approach to the Evaluation of Subjects at Risk of Sudden Death
下载免费PDF全文
![点击此处可从《Pacing and clinical electrophysiology : PACE》网站下载免费的PDF全文](/ch/ext_images/free.gif)
SILVIA PLACIDI M.D. FABRIZIO DRAGO M.D. MADDALENA MILIONI M.D. LETIZIA VERTICELLI C.C.P. ILARIA TAMBURRI C.C.P. MASSIMO STEFANO SILVETTI M.D. CORRADO DI MAMBRO M.D. DANIELA RIGHI M.D. FABRIZIO GIMIGLIANO M.D. MARIO SALVATORE RUSSO M.D. Ph.D. ROSALINDA PALMIERI M.D. ROMOLO REMOLI M.D. LORENZO MARIA SANTUCCI M.D. Ph.D. ALBERTO EUGENIO TOZZI M.D. 《Pacing and clinical electrophysiology : PACE》2016,39(7):669-674