全文获取类型
收费全文 | 1987574篇 |
免费 | 144287篇 |
国内免费 | 5670篇 |
专业分类
耳鼻咽喉 | 25513篇 |
儿科学 | 64456篇 |
妇产科学 | 51879篇 |
基础医学 | 296098篇 |
口腔科学 | 54971篇 |
临床医学 | 189226篇 |
内科学 | 382065篇 |
皮肤病学 | 41169篇 |
神经病学 | 160134篇 |
特种医学 | 72695篇 |
外国民族医学 | 435篇 |
外科学 | 281973篇 |
综合类 | 42593篇 |
现状与发展 | 3篇 |
一般理论 | 664篇 |
预防医学 | 162385篇 |
眼科学 | 44102篇 |
药学 | 147764篇 |
9篇 | |
中国医学 | 5224篇 |
肿瘤学 | 114173篇 |
出版年
2021年 | 16873篇 |
2019年 | 17429篇 |
2018年 | 24238篇 |
2017年 | 18415篇 |
2016年 | 20216篇 |
2015年 | 23056篇 |
2014年 | 31519篇 |
2013年 | 47830篇 |
2012年 | 65714篇 |
2011年 | 69305篇 |
2010年 | 40494篇 |
2009年 | 37549篇 |
2008年 | 63501篇 |
2007年 | 67488篇 |
2006年 | 67717篇 |
2005年 | 64940篇 |
2004年 | 62214篇 |
2003年 | 58881篇 |
2002年 | 57222篇 |
2001年 | 90512篇 |
2000年 | 92676篇 |
1999年 | 77509篇 |
1998年 | 22050篇 |
1997年 | 19445篇 |
1996年 | 19370篇 |
1995年 | 18448篇 |
1994年 | 17089篇 |
1993年 | 15919篇 |
1992年 | 60858篇 |
1991年 | 59672篇 |
1990年 | 57888篇 |
1989年 | 55787篇 |
1988年 | 51336篇 |
1987年 | 49915篇 |
1986年 | 47592篇 |
1985年 | 45204篇 |
1984年 | 33770篇 |
1983年 | 28797篇 |
1982年 | 16985篇 |
1979年 | 30665篇 |
1978年 | 21740篇 |
1977年 | 18025篇 |
1976年 | 17506篇 |
1975年 | 18376篇 |
1974年 | 22199篇 |
1973年 | 21547篇 |
1972年 | 20011篇 |
1971年 | 18608篇 |
1970年 | 17499篇 |
1969年 | 16031篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
51.
Votteler T. P. Lipsky K. 《世界核心医学期刊文摘》2006,2(2):31-31
背景/目的:从1978-2000年,有10对联体双胞胎成功接受了手术分离,结果14人存活。其中6对是因为他们的联体同胞死亡或濒临死亡而接受紧急分离手术。剩余的4对,每对至少一个同胞接受至少一次的急诊手术后,才接受联体分离手术。方法:对这一独特的队列进行包含6个项目的问卷调查。问题的设计是开放式的,为父母/家庭提供有关信息的最大机会。对每个家庭就相同的问题也进行了当面的问卷调查。医师询问了与身体健康和疾病相关的一些问题。而社会工作询问了与发育、教育、社会心理和家庭功能相关的问题。结果:前面提及的14人存活的双胞胎中,4人大学毕业,1人于1981年完成中学学业,剩余9人正在上学。14人在最初的手术后,还需要接受再次手术,尤其是需要矫正泌尿系统、畸形、神经外科和小儿外科的问题。结论:通过超声检查对联体双胎进行宫内诊断,可以使医师和胎儿父母在孕早期决定在终止妊娠时是进行双胎分离还是保全其中一个。这些病例报道通过描述14例手术存活的长期体格检查和心理学检查结果,为医师和父母在关键时刻做出决定提供了另外有助的依据。 相似文献
52.
53.
OBJECTIVE: To explore the presence and grade of denervation in three mimic muscles in facial nerve palsy. METHODS: The frontalis, orbicularis oculi (OO), and mentalis muscles were explored in 54 patients with Bell's palsy, after 30 days from the beginning of symptoms. Concentric needle electromyography, including fibrillation detection, was performed in the three muscles on the affected side. Compound muscle action potentials (CMAP) were recorded on both sides and a CMAP ratio was calculated from each muscle. The House-Brackman scale was used to assess the initial clinical evaluation and the follow-up until recovery. RESULTS: Fibrillation was recorded in 32 patients on the 30th day after the onset and was present in 100% of mentalis and in 90% of frontalis, but in only 34% of OO, a statistically significant difference. The grade of fibrillation in OO was also statistically lower from those in the other two muscles. The 32 patients were grouped according to the presence (A) or not (B) of fibrillation in OO. In group A, CMAP ratios (affected/normal side) did not differ significantly among the three muscles. However, in group B they were significantly greater in OO and frontalis than in mentalis. In between-group comparison, group B muscles had significantly higher CMAP ratios, lower degree of fibrillation, and better functional recovery. CONCLUSION: In facial palsy, the presence and grade of fibrillation in OO are lower than in frontalis and mentalis muscles and prognosis is more favorable for the non-fibrillating OO group of patients. 相似文献
54.
55.
56.
Here we report how the different types of regional muscle involvement, i.e. bulbar, ocular or generalized, in patients with myasthenia gravis (MG) influence the mental aspects of quality of life. Clinical examination according to Osserman was performed in 48 MG patients (45 women, three men; mean age 54, SD 12 years). Each patient was at the time for clinical evaluation asked to fill out the disease-specific Myasthenia Gravis Questionnaire (MGQ) and the Short-Form 36-item questionnaire for health survey (SF-36) as patient-oriented tools. We related the regional domains (generalized domain, bulbar domain and ocular domain) of the MGQ and the clinical findings, respectively, with mental quality of life as assessed by SF-36. Bulbar and generalized involvement results in impairment of mental aspects of quality of life, whereas ocular involvement does not. 相似文献
57.
TG Berger F Kiesewetter C Maczek N Bauer M Lueftl G Schuler M Simon Jr 《Journal of the European Academy of Dermatology and Venereology》2006,20(2):178-183
Vitiligo and psoriasis are both common skin disorders. However, psoriasis strictly confined to pre-existing vitiligo areas is rare and suggests a causal relationship. We report here on two patients with a strict anatomical colocalization of vitiligo and psoriasis. The histopathological examinations showed typical changes for both diseases together with a dense infiltrate of CD4+ and CD8+ T cells. By immunohistochemistry, intracytoplasmatic granzyme B and tumour necrosis factor alpha (TNF-alpha) were detected within the T-cell population, suggesting the functional activity of these cells and the creation of a local T helper 1 (Th1)-cytokine milieu. Additionally, in one patient we could identify anti-melanocytic T cells by tetramer staining and enzyme-linked immunospot (ELISPOT) analysis. These skin-infiltrating lymphocytes might trigger, by the local production of Th-1 cytokines such as TNF-alpha and interferon-gamma (IFN-gamma), the eruption of psoriatic plaques in patients with a genetic predisposition for psoriasis. 相似文献
58.
59.
R C Pattinson L C Snyman A P Macdonald 《Suid-Afrikaanse tydskrif vir geneeskunde》2006,96(11):1191-1194
AIM: To evaluate whether the introduction of a strict protocol approach based on the systemic evaluation of critically ill pregnant women with complications of abortion affected outcome. SETTING: Indigent South Africans managed in the regional and tertiary hospitals of the Pretoria Academic Complex. METHOD: Since 1997 a standard definition of severe acute maternal morbidity (SAMM) has been used in the Pretoria Academic Complex. All cases of SAMM and maternal deaths were entered on the Maternal Morbidity and Mortality Audit System programme. A comparison of outcome of severely ill women who had complications of abortion was made between 1997-1998 (original protocol) and 2002-2004 (strict protocol). OUTCOME MEASURES: The mortality index and prevalence of organ system failure or dysfunction. RESULTS: In 1997-1998 there were 43 women with SAMM who survived and a further 10 maternal deaths due to complications of abortion, compared with 107 women with SAMM and 7 maternal deaths during 2002-2004. The mortality index declined from 18.9% in 1997-1998 to 6.1% in 2002-2004 (p = 0.02, odds ratio 0.28, 95% confidence limits 0.10 - 0.79). Significantly more women had hypovolaemic shock in 2002-2004 compared with 1997-1998 (54.4% v. 35.8%, p = 0.04), but fewer women had immune system failure including septic shock (18.4% v. 47.2%, p = 0.0002) and metabolic dysfunction (0 v. 5.7%, p = 0.03) and there was a trend to less renal failure (10.5% v. 22.6%, p = 0.06) and cardiac failure (4.4% v. 13.2%, p = 0.08). CONCLUSION: The strict protocol approach based on systemic evaluation in managing critically ill pregnant women with complications of abortion, coupled with an intensive, regular feedback mechanism, has been associated with a reduction in the mortality index. 相似文献
60.
Philip A. Rozario Nancy L. Morrow-Howell Enola K. Proctor 《Quality of life research》2006,15(4):755-759
Using the SF-12 to measure physical and mental functioning, the authors examine the intra-individual changes in health-related
quality of life (HRQOL) 6 months post-discharge for depressed older adults. In addition, they examine three sets of predictors
that might influence these changes. The sample of depressed older adults was recruited from an inpatient geropsychiatry unit.
Although their physical and mental health scores on the SF-12 were lower than comparable norms, the sample showed an average
increase in their mental functioning but a decrease in the physical functioning over the 6 months. Negative life-events were
significant predictors of people who reported no change in their mental health functioning and decreases in their physical
health functioning. Interestingly, those who experienced positive life events were more likely to report declines and younger
participants were more likely to report no change in their physical functioning. The findings indicate that the effects of
depression on HRQOL can have enduring effects on a sample of previously hospitalized older adults. The significance of life
event changes might signify the importance of taking into account non-traditional areas of medical interventions. Further,
the findings indicate the usefulness of the SF-12 quantifying HRQOL outcomes. 相似文献