全文获取类型
收费全文 | 6187篇 |
免费 | 492篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 59篇 |
儿科学 | 223篇 |
妇产科学 | 147篇 |
基础医学 | 857篇 |
口腔科学 | 60篇 |
临床医学 | 711篇 |
内科学 | 1085篇 |
皮肤病学 | 162篇 |
神经病学 | 674篇 |
特种医学 | 126篇 |
外科学 | 754篇 |
综合类 | 44篇 |
一般理论 | 2篇 |
预防医学 | 818篇 |
眼科学 | 87篇 |
药学 | 433篇 |
中国医学 | 2篇 |
肿瘤学 | 445篇 |
出版年
2024年 | 5篇 |
2023年 | 72篇 |
2022年 | 126篇 |
2021年 | 260篇 |
2020年 | 178篇 |
2019年 | 230篇 |
2018年 | 288篇 |
2017年 | 209篇 |
2016年 | 194篇 |
2015年 | 245篇 |
2014年 | 308篇 |
2013年 | 412篇 |
2012年 | 575篇 |
2011年 | 507篇 |
2010年 | 285篇 |
2009年 | 242篇 |
2008年 | 346篇 |
2007年 | 340篇 |
2006年 | 333篇 |
2005年 | 320篇 |
2004年 | 275篇 |
2003年 | 265篇 |
2002年 | 225篇 |
2001年 | 32篇 |
2000年 | 35篇 |
1999年 | 31篇 |
1998年 | 48篇 |
1997年 | 27篇 |
1996年 | 22篇 |
1995年 | 16篇 |
1994年 | 17篇 |
1993年 | 17篇 |
1992年 | 17篇 |
1991年 | 18篇 |
1990年 | 15篇 |
1989年 | 15篇 |
1988年 | 11篇 |
1987年 | 13篇 |
1986年 | 11篇 |
1985年 | 9篇 |
1984年 | 5篇 |
1983年 | 9篇 |
1981年 | 7篇 |
1980年 | 5篇 |
1979年 | 9篇 |
1978年 | 5篇 |
1976年 | 6篇 |
1975年 | 10篇 |
1973年 | 6篇 |
1968年 | 4篇 |
排序方式: 共有6689条查询结果,搜索用时 31 毫秒
101.
102.
Carol Dawson-Rose PhD Deena Shehadeh MSN RN-BC PHN Jennifer Hao BA Jasmine Barnard BA Ladan Khoddam-Khorasani MPH Adam Leonard MS MPH CPNP AAHIVS Kristen Clark MSN RN Eva Kersey BA Haley Mousseau MA Julie Frank LCSW MSW Aaron Miller PMHNP Adam Carrico PhD Amy Schustack EdD Yvette P. Cuca PhD 《Public health nursing (Boston, Mass.)》2020,37(3):363-370
103.
War experiences may have an extensive impact on the health status of the exposed populations. This population‐based study aimed to examine the relationship between war experiences and self‐reported general health in representative sample surveys from Bosnia‐Herzegovina (n = 3,313) and Kosovo (n = 1,000). Data were collected with face‐to‐face interviews fielded in the winter of 2003–2004. Logistic regression analysis was used to compute unadjusted and adjusted odds ratios (ORs). The adjusted effects of the extensiveness of war experiences on poor health were positive in both countries, but they were statistically significant only for Bosnia‐Herzegovina: OR = 1.04, 95% CI [1.00, 1.08] for Bosnia‐Herzegovina and OR = 1.03, 95% CI [0.98, 1.09] for Kosovo. The strongest observed effect was found for Kosovo only: The extensiveness of war experiences was relatively strongly related to longstanding health problems, OR = 1.09, 95% CI [1.03, 1.15]. We found that war experiences may contribute to increased poorer health in the exposed populations; however, the effects 4–9 years after the war ended were modest. Hence, war experiences seemed to be more strongly related to war‐related distress and posttraumatic stress disorder than to self‐reported general health. 相似文献
104.
105.
Jing Qi Yuman Fong Leonard Saltz Michael I. D'Angelica Nancy E. Kemeny Mithat Gonen Jinru Shia Amita Shukla‐Dave William M. Jarnagin Richard K. G. Do Lawrence H. Schwartz Jason A. Koutcher Kristen L. Zakian 《NMR in biomedicine》2013,26(2):204-212
Hepatic steatosis is a hallmark of chemotherapy‐induced liver injury. We made serial 1H MRS measurements of hepatic lipids in patients over the time course of a 24‐week chemotherapeutic regimen to determine whether 1H MRS could be used to monitor the progression of chemotherapy‐induced steatosis. Thirty‐four patients with stage III or IV colorectal cancer receiving 5‐fluorouracil, folinic acid and oxaliplatin (n = 21) or hepatic arterial infusion of floxuridine with systemic irinotecan (n = 13) were studied prospectively. 1H MRS studies were performed at baseline and after 6 and 24 weeks of treatment. A 1H MR spectrum was acquired from the liver during a breath hold and the ratio of fat to fat + water (FFW) was calculated to give a measure of hepatic triglycerides (HTGCs). The methodology was histologically validated in 18 patients and the reproducibility was assessed in 16 normal volunteers. Twenty‐seven patients completed baseline, 6‐week and 24‐week 1H MRS examinations and one was censored. Thirteen of 26 patients (50%) showed an increase in FFW after completion of treatment. Six patients (23%) developed hepatic steatosis and two patients converted from steatosis to nonsteatotic liver. Patients whose 6‐week hepatic lipid levels had increased significantly relative to baseline also had a high probability of lipid elevation relative to baseline at the completion of treatment. Serial 1H MRS is effective for the monitoring of HTGC changes during chemotherapy and for the detection of chemotherapy‐associated steatosis. Six of 26 patients developed steatosis during chemotherapy. Lipid changes were observable at 6 weeks. Copyright © 2012 John Wiley & Sons, Ltd. 相似文献
106.
The Patient Protection and Affordable Care Act (ACA) continues to be the subject of fierce political debate in the United States. Drawing on issue framing theory, together with research on wording effects in survey responding, we tested how common differences in the wording of ACA surveys relate to apparent public support for the law. We report on a content analysis of N = 376 U.S. national opinion surveys fielded during a more than six-year period, beginning 23 March 2010 (when President Obama signed the bill into law) and ending 8 November 2016 (Election Day), and use ordinary least squares (OLS) regression models to predict public support for the law as a function of variation in question wording. We coded questions gauging general sentiment toward the law for differences in issue labeling (e.g., Obamacare, Affordable Care Act), whether or not they referenced particular political entities (e.g., President Obama, Congress) or segments of the public (e.g., You, Your Family), various opinion metrics (e.g., Support, Favor), and different response options (e.g., Repeal, Expand) which we used to model aggregate levels of support. The results revealed several key differences in question wording—for example, generic references to the Healthcare Law were employed much more frequently than Obamacare or Affordable Care Act—a number of which reliably predicted aggregate levels of public support. The discussion considers possible explanations for these patterns and reiterates the value of attending to questionnaire design features when interpreting survey data about politically contentious health policy issues. 相似文献
107.
Kristen H. Fernandez M.D. Peter Rady M.D. Ph.D. Steven Tyring M.D. Ph.D. M.B.A. Mary S. Stone M.D. 《Pediatric dermatology》2014,31(3):400-402
Abstract: A 4‐year‐old girl with an established diagnosis of atopic dermatitis, previously severe and treated with cyclosporine, developed widespread papules that demonstrated changes consistent with epidermodysplasia verruciformis on biopsy. Human papilloma virus (HPV) typing was performed and was consistent with epidermodysplasia verruciformis‐type HPV (type 5). These lesions rapidly resolved with a 2‐week course of imiquimod. Rapid resolution and no family history of epidermodysplasia verruciformis make this most consistent with acquired epidermodysplasia verruciformis. This case is the first reported case of acquired epidermodysplasia verruciformis in a child without the human immunodeficiency virus and may be linked to cyclosporine use, which also has never been previously reported. 相似文献
108.
109.
110.
The retina is one of the most energy demanding tissues in the body. Like most neurons in the central nervous system, retinal neurons consume high amounts of adenosine-5′-triphosphate(ATP) to generate visual signal and transmit the information to the brain. Disruptions in retinal metabolism can cause neuronal dysfunction and degeneration resulting in severe visual impairment and even blindness. The homeostasis of retinal metabolism is tightly controlled by multiple signaling pathways, such as the unfolded protein response(UPR), and the close interactions between retinal neurons and other retinal cell types including vascular cells and Müller glia. The UPR is a highly conserved adaptive cellular response and can be triggered by many physiological stressors and pathophysiological conditions. Activation of the UPR leads to changes in glycolytic rate, ATP production, de novo serine synthesis, and the hexosamine biosynthetic pathway, which are considered critical components of Müller glia metabolism and provide metabolic support to surrounding neurons. When these pathways are disrupted, neurodegeneration occurs rapidly. In this review, we summarize recent advance in studies of the UPR in Müller glia and highlight the potential role of the UPR in retinal degeneration through regulation of Müller glia metabolism. 相似文献