Imaging of acute pulmonary embolism

Acute pulmonary thromboembolism (PE) is a cardiovascular emergency associated with significant morbidity and a 5–35 % mortality for untreated pulmonary embolism. If promptly diagnosed and treated, the mortality rate can be significantly reduced. Diagnosis of acute PE continues to be a clinical challenge, with diagnostic imaging playing an important role. This review discusses the clinical challenges of diagnosing acute PE, presents an evidence-based review of the current tests and ever-evolving imaging technology, and highlights special considerations related to radiation dose, contrast media use, and pregnant patients.     

Therapy-Induced Changes in CXCR4 Expression in Tumor Xenografts Can Be Monitored Noninvasively with N-[11C]Methyl-AMD3465 PET

Molecular Imaging and Biology - Chemokine CXCL12 and its receptor CXCR4 are constitutively overexpressed in human cancers. The CXCL12-CXCR4 signaling axis plays an important role in tumor...