全文获取类型
收费全文 | 19961篇 |
免费 | 974篇 |
国内免费 | 116篇 |
专业分类
耳鼻咽喉 | 256篇 |
儿科学 | 377篇 |
妇产科学 | 239篇 |
基础医学 | 2477篇 |
口腔科学 | 484篇 |
临床医学 | 1276篇 |
内科学 | 5010篇 |
皮肤病学 | 300篇 |
神经病学 | 1560篇 |
特种医学 | 1012篇 |
外科学 | 3830篇 |
综合类 | 72篇 |
一般理论 | 3篇 |
预防医学 | 478篇 |
眼科学 | 184篇 |
药学 | 1161篇 |
中国医学 | 33篇 |
肿瘤学 | 2299篇 |
出版年
2023年 | 129篇 |
2022年 | 254篇 |
2021年 | 439篇 |
2020年 | 211篇 |
2019年 | 351篇 |
2018年 | 410篇 |
2017年 | 357篇 |
2016年 | 407篇 |
2015年 | 445篇 |
2014年 | 539篇 |
2013年 | 652篇 |
2012年 | 1111篇 |
2011年 | 1160篇 |
2010年 | 707篇 |
2009年 | 592篇 |
2008年 | 1109篇 |
2007年 | 1227篇 |
2006年 | 1184篇 |
2005年 | 1187篇 |
2004年 | 1153篇 |
2003年 | 1094篇 |
2002年 | 1110篇 |
2001年 | 426篇 |
2000年 | 398篇 |
1999年 | 421篇 |
1998年 | 335篇 |
1997年 | 221篇 |
1996年 | 238篇 |
1995年 | 142篇 |
1994年 | 162篇 |
1993年 | 142篇 |
1992年 | 268篇 |
1991年 | 222篇 |
1990年 | 208篇 |
1989年 | 185篇 |
1988年 | 224篇 |
1987年 | 189篇 |
1986年 | 145篇 |
1985年 | 164篇 |
1984年 | 122篇 |
1983年 | 118篇 |
1982年 | 56篇 |
1981年 | 51篇 |
1980年 | 49篇 |
1979年 | 81篇 |
1978年 | 75篇 |
1977年 | 58篇 |
1976年 | 50篇 |
1974年 | 52篇 |
1972年 | 57篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
21.
22.
Shang-Jin Shi Hiromi Rakugi Koichi Higashimori Jitsuo Higaki Hiroshi Mikami Toshio Ogihara 《Clinical and experimental pharmacology & physiology》1994,21(10):767-773
1. We previously reported that angiotensin II release from the mesenteric arteries of Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR) increased in a time-dependent manner as a result of the isolation of the arteries and perfusion. This phenomenon appeared to be due to the withdrawal of circulating angiotensin II (AII). 2. The purpose of the present study was to test the hypothesis that vascular AII generation may be negatively regulated by circulating AII in WKY and SHR, and to clarify the role of this vascular angiotensin II in the sustained hypertension of SHR following nephrectomy. 3. The mesenteric arteries from kidney-intact and nephrectomized WKY and SHR were perfused and the amount of AII released into the perfusate was measured. The effects of the angiotensin converting enzyme inhibitor, captopril, and the effects of supplementation of renal renin and circulating angiotensins to nephrectomized rats, by blood exchange between kidney-intact and nephrectomized rats, on AII release were examined to clarify the pathway of vascular AII generation after nephrectomy. 4. Nephrectomy caused augmentation of vascular AII release both in WKY and SHR in spite of the abolishment of circulating renin. Captopril reduced this enhanced release of AII, but blood exchange did not affect it. There was no significant difference in these responses between WKY and SHR. 5. These results suggest that WKY and SHR have in common a potent pathway for production of vascular AII in response to the withdrawal of circulating AII, although this pathway is not responsible for the sustained hypertension of SHR after nephrectomy. The precise pathophysiological role of this pathway remains to be elucidated. 相似文献
23.
24.
Koichi Fujiu Ryuzo Kanno Yutaka Shio Jyun Ohsugi Yoshihiro Nozawa Mitsukazu Gotoh 《General thoracic and cardiovascular surgery》2004,52(7):345-348
A 36-year-old woman complained of cough and high fever. Computed tomographic scans demonstrated a mediastinal mass. A couple of months later, she developed dryness in her eyes and mouth. Biopsy of the lip confirmed the diagnosis of Sjögren’s syndrome. She underwent thymo-thymomectomy. Pathological findings of the mass revealed thymoma. At two months after surgery, she developed ptosis and dysphagia that were compatible with myasthenia gravis. The clinical symptoms were adequately controlled with prednisolone. At eleven months after surgery, she presented with severe anemia, which led to the diagnosis of pure red cell aplasia. The following treatment with cyclosporin caused hemoglobin concentration to rise. However, she continues to suffer from dryness of her eyes and mouth. The case is the first to be reported with Sjögren’s syndrome and the triad of thymoma, myasthenia gravis and pure red cell aplasia, and is compared with previously reported cases of the three conditions. 相似文献
25.
26.
27.
28.
29.
Yasuhiro Takikawa Yuki Yasumi Akihiro Sato Ryujin Endo Kazuyuki Suzuki Yasuki Mori Hidetoshi Akasaka Yasuhiro Miura Takashi Sawai Hiroaki Okamoto 《Hepatology research》2007,37(2):158-165
A 65-year-old Japanese man was hospitalized because of acute hepatitis and severe cholestasis due to hepatitis E virus (HEV) infection combined with a drug reaction to a cold preparation. He died of disseminated intravascular coagulation and severe intestinal bleeding due to systemic cytomegalovirus reactivation following the development of severe eruptions with marked eosinophilia due to drug hypersensitivity to taurine and ursodeoxycholate preparations. The close interaction between viral infection or reactivation and drug hypersensitivity was considered as a pathophysiology in this case, which emphasizes the need for further study of the immunological mechanism of the interaction. 相似文献
30.
Shuro Yoshino Takayuki Matsumoto Koichi Kurahara Hiroyuki Kobayashi Mitsuo Iida Tadahiko Fuchigami 《Digestive endoscopy》2006,18(1):59-61
We present a 70‐year‐old man who had two episodes of melena during the preceding 8‐year period. He had a Dieulafoy‐like lesion in a diverticulum in the third portion of the duodenum. While emergency endoscopy revealed neither apparent blood nor clots around the diverticular orifice, there was a non‐bleeding vessel in the fundus of the diverticulum. The vessel ceased bleeding after argon plasma coagulation and, since then, the patient has not experienced bleeding. In cases of gastrointestinal bleeding of obscure origin, duodenal diverticulum should be considered as a possible source of bleeding, even when endoscopy discloses no apparent bleeding. 相似文献