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81.
82.
Vierk KA Koehler KM Fein SB Street DA 《The Journal of allergy and clinical immunology》2007,119(6):1504-1510
BACKGROUND: Few population-based studies in the United States have determined the prevalence of food allergy in adults and the problems these individuals might have with reading food labels. OBJECTIVE: The objectives of this study are to report the prevalence of self-reported food allergy, to identify the characteristics of food allergy reactions, and to describe the use of labels among adults with food allergy. METHODS: Questions from the US Food and Drug Administration's 2001 Food Safety Survey were analyzed to determine the prevalence of food allergy and opinions about food labels in the management of food allergy. RESULTS: The prevalence of self-reported food allergy is 9.1% among all survey respondents, with 5.3% of all respondents reporting a doctor-diagnosed food allergy. The prevalence of food allergy to the 8 most common allergens (peanut, tree nuts, egg, milk, wheat, soybeans, fish, and crustacean shellfish) is self-reported as 2.7% among respondents with doctors' diagnoses. Several label issues, such as words on some ingredient lists being too technical or hard to understand and food labels not always alerting persons to new ingredients, were reported as serious or very serious obstacles for managing an allergy. CONCLUSION: The prevalence of self-reported doctor-diagnosed food allergy among US adults is 5.3%, and a large portion of adults with food allergy found certain label issues a serious problem for managing their food allergy. CLINICAL IMPLICATIONS: The findings provide a needed source of population-based prevalence data of food allergy among US adults. Label issues identified are useful in understanding the difficulties of managing a food allergy. 相似文献
83.
Eremeeva ME Gerns HL Lydy SL Goo JS Ryan ET Mathew SS Ferraro MJ Holden JM Nicholson WL Dasch GA Koehler JE 《The New England journal of medicine》2007,356(23):2381-2387
Bartonella species cause serious human infections globally, including bacillary angiomatosis, Oroya fever, trench fever, and endocarditis. We describe a patient who had fever and splenomegaly after traveling to Peru and also had bacteremia from an organism that resembled Bartonella bacilliformis, the causative agent of Oroya fever, which is endemic to Peru. However, genetic analyses revealed that this fastidious bacterium represented a previously uncultured and unnamed bartonella species, closely related to B. clarridgeiae and more distantly related to B. bacilliformis. We characterized this isolate, including its ability to cause fever and sustained bacteremia in a rhesus macaque. The route of infection and burden of human disease associated with this newly described pathogen are currently unknown. 相似文献
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Petra Langerbeins Moritz Fürstenau Henning Gruell Florian Klein Thorsten Persigehl Jan Rybniker Tamina Seeger-Nukpezah Matthias Kochanek Michael Hallek Barbara Eichhorst Philipp Koehler Boris Böll 《European journal of haematology》2020,105(4):508-511
The number of people suffering from the new coronavirus SARS-CoV-2 continues to rise. In SARS-CoV-2, superinfection with bacteria or fungi seems to be associated with increased mortality. The role of co-infections with respiratory viral pathogens has not yet been clarified. Here, we report the course of COVID-19 in a CLL patient with secondary immunodeficiency and viral co-infection with parainfluenza. 相似文献
87.
Michael F. T. Koehler Philippe Bergeron Edna F. Choo Kevin Lau Chudi Ndubaku Danette Dudley Paul Gibbons Brad E. Sleebs Carl S. Rye George Nikolakopoulos Chinh Bui Sanji Kulasegaram Wilhelmus J. A. Kersten BrianJ. Smith Peter E. Czabotar Peter M. Colman DavidC. S. Huang Jonathan B. Baell Keith G. Watson Lisa Hasvold Zhi-Fu Tao Le Wang AndrewJ. Souers Steven W. Elmore John A. Flygare Wayne J. Fairbrother Guillaume Lessene 《ACS medicinal chemistry letters》2014,5(6):662-667
88.
由于采用血浆置换(PE)治疗血栓性血小板减少性紫癜溶血性尿毒综合征(TTP HUS)频率的增加,PE引起的并发症也成为制定治疗方案时需要考虑的因素。由于TTP HUS的诊断常常是不确定的,掌握PE治疗利弊之间的平衡已成为制定适当治疗方案的焦点。之前,我们于1996年~2002年间曾两次报道 相似文献
89.
In this study, we calculated the energetics of hydrogen atoms adsorbing on and diffusing into the first few layers of γ-Fe for the (100), (110) and (111) surfaces and for the non-magnetic (NM), ferromagnetic (FM), and antiferromagnetic single (AFM1) and double layer (AFMD) structures. These studies are relevant as they atomistically simulate the early stages of hydrogen embrittlement in steels. We employed density functional theory to establish adsorption sites and energies for each plane and the minimum energy pathways for diffusion through the first few layers with associated activation barriers. Adsorption energies for all cases vary between ∼3.7 and 4.4 eV, and the energy barriers to diffusion in the bulk region vary between ∼0.2 and 1.2 eV for the twelve cases, with the highest and lowest bulk diffusion barriers occurring in the NM(111) and the FM(100) case, respectively. We conclude that the texturing of steels in order to expose certain cleavage planes or magnetic structures can decrease the likelihood of hydrogen embrittlement.Calculations of adsorption and diffusion energies of hydrogen on and through iron relevant to hydrogen embrittlement. 相似文献
90.
M S Shin R E Koehler R J Stanley J C Barton K J Ho 《The Journal of computed tomography》1987,11(3):297-300
Computed tomography and magnetic resonance imaging of a malignant hemangiopericytoma in a 58-year-old woman are described. The tumor was initially found in the abdomen and resected 34 years ago, but recurred 18 years later, followed by repeated recurrence and eventually metastasis to the lung and then to the liver. The lung nodules were round or oval, homogeneous, and well circumscribed while the massive tumor in the right lobe of the liver was poorly delineated with irregular areas of cystic necrosis. With proper setting of the repetition time and echo delay, the metastatic tumor became distinct from the uninvolved hepatic tissue on magnetic resonance imaging. In this case computed tomography and magnetic resonance imaging were complementary in evaluation of such a tumor. 相似文献