Beitrag zur Dynamik des Gesunden und Kranken Herzens Unter Belastung,Insbesondere Beim Übergang von Körperruhe zu Körperlicher Arbeit

Ohne Zusammenfassung     

Über Einige Beziehungen der Lungen-, Herz- und Kreislauffunktion zum Gesamtstoffwechsel vom Standpunkt der Klinik

Ohne Zusammenfassung     

Der fibrovasculäre Oesophaguspolyp – Diagnostik und Therapie

Zusammenfassung. Fibrovascul?re Polypen sind sehr seltene gutartige Neubildungen der Speiser?hre. Eindrücklichstes klinisches Symptom ist die enorale Tumorregurgitation, die bei pharyngealer Einklemmung zur Asphyxie führen kann. Gew?hnlich macht sich der fibrovascul?re Oesophaguspolyp jedoch durch dysphagische Beschwerden und zunehmenden Gewichtsverlust bemerkbar. Die Diagnosesicherung durch Oesophagogastroskopie und Oesophagusbreischluck erweist sich wider Erwarten oftmals als schwierig. H?ufigste Fehldiagnosen sind die der Achalasie oder einer intramuralen bzw. mediastinalen, den Oesophagus imprimierenden Raumforderung. CT und MRT tragen wenig zur Diagnosefindung bei. Kleine Polypen k?nnen einer endoskopischen Abtragung mit Diathermieschlinge oder Nd-YAG-Laser zugeführt werden. Gew?hnlich ist jedoch eine chirurgische Intervention erforderlich. Bei zumeist subcricoidalem Sitz der Polypenbasis erfolgt die Tumorexposition und Resektion durch eine Oesophagotomie über einen linkscervicalen Zugang. Eine Thoracotomie ist selten indiziert.      

Venöse Malformation der Wange

Venous malformations as a cause of space-occupying lesions in the head and neck region are rare, especially at an advanced age. We report on a 74-year-old female patient with a venous malformation of the cheek and its successful surgical treatment.     

Effects of Cytokines, Butyrate and Dexamethasone on Serum Amyloid A and Apolipoprotein A-I Synthesis in Human HUH-7 Hepatoma Cells

Serum amyloid A (SAA) and apolipoprotein A-I (apo A-I) are secreted by the liver. As concentrations of both apolipoproteins are inversely related under normal and acute-phase conditions, human HUH-7 hepatoma cells were stimulated with interleukin (IL)-1alpha (100 and 200 U), IL-6 (50 and 100 U), butyrate (2 mM) and dexamethasone (2 x 10(-7)M and 1 x 10(-6)M), alone or in combination. Changes in SAA and apo A-I synthesis were monitored after metabolic labelling of the cells with [35S]-methionine. Intracellular and secreted SAA and apo A-I were immunoprecipitated, separated by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), and the radioactivity in the corresponding bands was counted. Intracellular apolipoprotein levels were increased by all stimuli, either alone or in combination, between 2.7- and 5.5-fold (SAA) and between 2.8- and 4.1-fold (apo A-I), respectively. In a similar manner, apolipoprotein levels secreted by HUH-7 cells were increased between 3.1- and 4.3-fold (SAA) and between 1.9- and 3. 3-fold (apo A-I). Co-administration of cytokines, butyrate and/or dexamethasone had no pronounced synergistic effect on intracellular biosynthesis and secretion of SAA and apo A-I. The results from the present study suggest that apo A-I must not necessarily be considered as a negative acute-phase reactant.     

Erste Erfahrungen mit medizinischem Honig in der Wundbehandlung im Kopf-Hals-Bereich

Background

Already in ancient times honey was used as a drug and for the treatment of wounds. In recent years the different effects of honey on wound-healing processes have been reexamined. Based on this, the antibacterial and fungicidal qualities of honey could be confirmed.

Patients and Methods

Between January 2009 and July 2011 medical honey was used on 36 patients suffering from different wound-healing disorders in the head and neck area after unsuccessful conventional treatment. The healing process was registered by microbiological investigations, measurements of the wound edges and adequate photo documentation.

Results

Medical honey can be used without problems or detectable side effects on problematic wounds of the head and neck area. Constant treatment leads to fast wound lavation, granulation, reduction of putrid smells and a decrease in inflammation.

Conclusions

In the treatment of poorly healing and infected wounds within the head and neck area, medical honey can be used successfully without problems as an effective alternative to conventional treatment options.     

Tumoren und tumorähnliche Erkrankungen

Tumors and tumor-like lesions are rare diseases in the paranasal sinuses.There is a great variety of histological types, but only a small number of morphological patterns on imaging. Histology is an important point in therapeutic planning. In most cases it is obtained by sampling, which is not as difficult in the sinonasal area as in other regions of the body. The main task of imaging is an exact estimation of the extent and spread of a lesion. This article discusses the possibilities and limitations of CT and MRI in the assessment of the dignity and spread of paranasal tumors and tumor-like lesions in consideration of necessary therapeutic information. Additionally, an overview of features on imaging of different paranasal tumors and tumor-like lesions is given.