全文获取类型
收费全文 | 436篇 |
免费 | 20篇 |
国内免费 | 9篇 |
专业分类
儿科学 | 20篇 |
妇产科学 | 5篇 |
基础医学 | 33篇 |
口腔科学 | 14篇 |
临床医学 | 49篇 |
内科学 | 118篇 |
皮肤病学 | 9篇 |
神经病学 | 9篇 |
特种医学 | 106篇 |
外科学 | 35篇 |
综合类 | 30篇 |
预防医学 | 11篇 |
眼科学 | 5篇 |
药学 | 2篇 |
肿瘤学 | 19篇 |
出版年
2023年 | 1篇 |
2021年 | 1篇 |
2020年 | 1篇 |
2019年 | 2篇 |
2018年 | 3篇 |
2017年 | 4篇 |
2016年 | 1篇 |
2015年 | 9篇 |
2014年 | 7篇 |
2013年 | 9篇 |
2011年 | 9篇 |
2010年 | 20篇 |
2009年 | 18篇 |
2008年 | 6篇 |
2007年 | 14篇 |
2006年 | 14篇 |
2005年 | 6篇 |
2004年 | 17篇 |
2003年 | 3篇 |
2002年 | 3篇 |
2001年 | 8篇 |
2000年 | 2篇 |
1999年 | 5篇 |
1998年 | 26篇 |
1997年 | 25篇 |
1996年 | 36篇 |
1995年 | 20篇 |
1994年 | 14篇 |
1993年 | 19篇 |
1992年 | 3篇 |
1991年 | 8篇 |
1990年 | 10篇 |
1989年 | 11篇 |
1988年 | 17篇 |
1987年 | 13篇 |
1986年 | 14篇 |
1985年 | 10篇 |
1984年 | 9篇 |
1983年 | 12篇 |
1982年 | 8篇 |
1981年 | 13篇 |
1980年 | 7篇 |
1979年 | 1篇 |
1978年 | 5篇 |
1977年 | 7篇 |
1976年 | 7篇 |
1975年 | 4篇 |
1973年 | 2篇 |
1972年 | 1篇 |
排序方式: 共有465条查询结果,搜索用时 234 毫秒
41.
Chimowitz MI Lynn MJ Derdeyn CP Turan TN Fiorella D Lane BF Janis LS Lutsep HL Barnwell SL Waters MF Hoh BL Hourihane JM Levy EI Alexandrov AV Harrigan MR Chiu D Klucznik RP Clark JM McDougall CG Johnson MD Pride GL Torbey MT Zaidat OO Rumboldt Z Cloft HJ;SAMMPRIS Trial Investigators 《The New England journal of medicine》2011,365(11):993-1003
42.
G Zaidi RP Sahu L Zhang G George N Bhavani N Shah V Bhatia A Bhansali G Jevalikar RV Jayakumar GS Eisenbarth E Bhatia 《Clinical genetics》2009,76(5):441-448
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare recessive disorder resulting from mutations in the autoimmune regulator ( AIRE ) gene. There is no information on AIRE mutations in Indians. In a cross-sectional study, nine patients (eight families), from four referral hospitals in India, were studied for AIRE mutations by direct sequencing. We screened for new mutations in 150 controls by allele-specific PCR. The patients had 1–7 known components of APECED. Three patients had unusual manifestations: presentation with type 1 diabetes; chronic sinusitis and otitis media; and facial dysmorphism. All patients carried homozygous, probably recessive, AIRE mutations. Two unrelated patients from a small in-bred community (Vanika Vaisya) in south India carried an unreported missense mutation, p.V80G, in the N-terminal caspase recruitment domain. Another unique mutation, p.C302X, resulting in a truncated protein with deletion of both zinc-finger domains, was detected in a patient from Gujarat. Neither mutation was detected in controls. Other mutations, previously described in Caucasians, were: 13 base pair deletion (p.C322fsX372) in 4 (38%), and Finn-major (p.R257X) and p.R139X (Sardinian) mutation in one subject each. In conclusion, in this first series of APECED in Indians, we detected AIRE mutations previously reported in Caucasians, as well as unique mutations. Of these, p.V80G is possibly an ancestral mutation in an in-bred community. 相似文献
43.
Silvio ST Tafuri Domenico DM Martinelli Giovanni GC Caputi Annamaria AA Arbore Cinzia CG Germinario Rosa RP Prato 《BMC health services research》2009,9(1):100-5
Background
Mandatory vaccination has contributed to the success of immunisation programmes but voluntary vaccination allows people to be responsible for their own health. There are benefits from both policies and the arguments between them remain subject to debate within and without the scientific community, both nationally and internationally. The aim of this study is to assess the opinions of those who actually work in the Vaccination Service. 相似文献44.
45.
Maria CLG Santos P Suzanne Hart Mukundhan Ramaswami Cláudia M Kanno Thomas C Hart Sergio RP Line 《Head & face medicine》2007,3(1):1-7
Background
Functional rehabilitation of patients afflicted with severe mandibular and maxillary alveolar atrophy might be challenging especially in malformed patients.Methods
Treatment planning using sinus lifting and implant placement before Le Fort I maxillary osteotomy in a patient with severe mandibular and posterior maxillary alveolar atrophy and skelettal class-III conditions due to cleft palate are described.Results
A full functional and esthetic rehabilitation of the patient was achieved by a stepwise surgical approach performed through sinus lifting as the primary approach followed by implant placement and subsequent Le Fort I maxillary osteotomy to correct the maxillo-mandibular relation.Conclusion
Stabilisation of the maxillary complex by a sinus lifting procedure in combination with computer aided implant placement as preorthodontic planning procedure before Le Fort I maxillary osteotomy seems to be suitable in order to allow ideal oral rehabilitation especially in malformed patients. 相似文献46.
Christof Karmonik Christopher Yen Orlando Diaz Richard Klucznik Robert G. Grossman Goetz Benndorf 《Acta neurochirurgica》2010,152(8):1391-1398
Purpose
To assess reliability of wall shear stress (WSS) calculations using computational fluid dynamics (CFD) dependent on inflow in internal carotid artery aneurysms (ICA). 相似文献47.
48.
49.
BC SHARMA RP SINGH YK CHAWLA KL NARASIMHAN KLN RAO SK MITRA JB DILAWARI 《Journal of gastroenterology and hepatology》1997,12(8):582-584
Shunt surgery is considered to be the treatment of choice in patients with non-cirrhotic portal hypertension. There is little data on the effect of side-to-side lieno-renal (SSLR) shunt on oesophageal variceal size, splenic size and splenic pulp pressure (SPP) in patients with non-cirrhotic portal hypertension. We evaluated pre- and postoperatively endoscopic grading of varices, splenic size and SPP for predicting shunt patency in 86 patients with non-cirrhotic portal hypertension: 56 with extrahepatic portal venous obstruction (EHPVO) and 30 with non-cirrhotic portal fibrosis (NCPF). The EHPVO patients with patent shunts (n= 47) showed significant reduction in SPP (pre-operative 43.56±7.9 vs postoperative 29.96±7.7 cm of saline), splenic size (6.5±2.8 vs 4.00±2.6 cm below costal margin) and varices grades (2.96±0.5 vs 0.92±0.8). Patients with blocked shunt (n= 9) did not show significant reduction in SPP and varices grades. However, there was reduction in spleen size (8.6±3.0 vs 6.3±4.3). In the NCPF group, 28 had patent shunts and showed significant reduction in SPP (46.3±13.5 vs 33.8±7.6 cm of saline), splenic size (9.1±3.3 vs 6.8±4.6 cm below costal margin) and varices grades (2.8±0.7 vs 1.05±0.96). As only two patients with NCPF had blocked shunts, no statistical comparison between patients with patent and patients with blocked shunts could be done. In conclusion, following SSLR, there is a significant reduction in SPP and varices grades in patients with patent shunts. Endoscopic grading of varices can be used to predict shunt patency. However, spleen size is not a good criteria for predicting shunt patency. 相似文献
50.