全文获取类型
收费全文 | 2497篇 |
免费 | 144篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 22篇 |
儿科学 | 27篇 |
妇产科学 | 20篇 |
基础医学 | 299篇 |
口腔科学 | 63篇 |
临床医学 | 162篇 |
内科学 | 561篇 |
皮肤病学 | 25篇 |
神经病学 | 353篇 |
特种医学 | 87篇 |
外科学 | 549篇 |
综合类 | 9篇 |
预防医学 | 39篇 |
眼科学 | 3篇 |
药学 | 108篇 |
中国医学 | 1篇 |
肿瘤学 | 328篇 |
出版年
2024年 | 2篇 |
2023年 | 25篇 |
2022年 | 43篇 |
2021年 | 107篇 |
2020年 | 53篇 |
2019年 | 57篇 |
2018年 | 67篇 |
2017年 | 53篇 |
2016年 | 67篇 |
2015年 | 64篇 |
2014年 | 95篇 |
2013年 | 104篇 |
2012年 | 158篇 |
2011年 | 166篇 |
2010年 | 99篇 |
2009年 | 83篇 |
2008年 | 147篇 |
2007年 | 162篇 |
2006年 | 160篇 |
2005年 | 174篇 |
2004年 | 161篇 |
2003年 | 120篇 |
2002年 | 145篇 |
2001年 | 27篇 |
2000年 | 35篇 |
1999年 | 20篇 |
1998年 | 32篇 |
1997年 | 40篇 |
1996年 | 25篇 |
1995年 | 14篇 |
1994年 | 19篇 |
1993年 | 13篇 |
1992年 | 10篇 |
1991年 | 8篇 |
1990年 | 9篇 |
1989年 | 10篇 |
1988年 | 18篇 |
1987年 | 12篇 |
1986年 | 12篇 |
1985年 | 7篇 |
1984年 | 9篇 |
1983年 | 5篇 |
1982年 | 1篇 |
1981年 | 6篇 |
1980年 | 3篇 |
1979年 | 2篇 |
1978年 | 3篇 |
1976年 | 2篇 |
1966年 | 2篇 |
排序方式: 共有2656条查询结果,搜索用时 109 毫秒
61.
Matsuda Hiroshi Okita Kyoji Motoi Yumiko Mizuno Toshiki Ikeda Manabu Sanjo Nobuo Murakami Koji Kambe Taiki Takayama Toshiki Yamada Kei Suehiro Takashi Matsunaga Keiko Yokota Takanori Tateishi Ukihide Shigemoto Yoko Kimura Yukio Chiba Emiko Kawashima Takahiro Tomo Yui Tachimori Hisateru Kimura Yuichi Sato Noriko 《Annals of nuclear medicine》2022,36(12):1039-1049
Annals of Nuclear Medicine - Amyloid positron emission tomography (PET) can reliably detect senile plaques and fluorinated ligands are approved for clinical use. However, the clinical impact of... 相似文献
62.
Konno S Murata M Toda T Yoshii Y Nakazora H Nomoto N Sugimoto H Nemoto H Wakata N Fujioka T Kurihara T 《Internal medicine (Tokyo, Japan)》2008,47(1):65-67
The clinical features of familial Creutzfeldt-Jakob disease with a codon 200 point mutation [fCJD (E200K)] are similar to those of sporadic CJD (sCJD). MRI diffusion-weighted imaging (MRI-DWI) has been reported to be useful for the early diagnosis of CJD. We describe a Japanese fCJD (E200K) case in which thalamic symptoms were the initial manifestations. On admission, electroencephalography (ECG) showed no periodic synchronous discharge (PSD), and MRI showed no abnormalities. However, single photon emission computed tomography (SPECT) using (99m)Tc-ethyl cysteinate dimer ((99m)Tc-ECD) revealed hypoperfusion in the right thalamus. We conclude that the thalamic form of CJD tends to show no high-intensity area (HIA) by MRI-DWI, and that SPECT may be more useful for visualizing the affected area responsible for the thalamic symptoms at an early stage. 相似文献
63.
64.
Recently, viruses have been regarded as useful molecular assemblies for materials applications rather than as disease-causing agents. The orderly assembled structures of the viruses are highly related to the resultant properties and functions of the assemblies; however, methods to control the assembly are still limited. Here, we demonstrated the assembly of filamentous viruses into hierarchical nano- to microstructures at liquid/liquid interfaces through emulsification in a controlled manner. The viruses form fibrous nanostructures of several micrometers length, which are much longer than the original virus. Subsequently, the fibers self-assemble into well-packed ordered microstructures. Furthermore, the resultant hierarchically assembled structures showed long-term stability and potential applicability through the desired functionalization.Assembly of filamentous viruses into hierarchical nano- to microstructures in a controlled manner was demonstrated using the liquid/liquid interface. 相似文献
65.
Yasunori FUJIMOTO Henrique F. RAMOS Pedro P. MARIANI Fabrizio R. ROMANO Arthur CUKIERT Edson BOR-SENG-SHU Akatsuki WAKAYAMA Toshiki YOSHIMINE 《Neurologia medico-chirurgica》2015,55(4):345-350
We describe a practical technique of superior turbinectomy followed by posterior ethmoidectomy as a less invasive procedure for two-surgeon technique on endoscopic endonasal transsphenoidal surgery. After identification of the superior turbinate and the sphenoid ostium, the inferior third portion of the superior turbinate was coagulated and resected. This partial superior turbinectomy procedure exposed the posterior ethmoidal sinus. Resection of the bony walls between the sphenoid and posterior ethmoid sinuses provided more lateral and superior exposure of the sphenoid sinus. This technique was performed in 56 patients with midline skull base lesions, including 49 pituitary adenomas and 7 other lesions. Meticulous manipulation of instruments was performed in all cases without surgical complications such as permanent hyposmia/anosmia or nasal bleeding. Our findings suggested that the partial superior turbinectomy followed by retrograde posterior ethmoidectomy is a simple and safe technique providing a sufficient surgical corridor for two-surgeon technique to approaching midline skull base regions, mainly involving pituitary adenomas. 相似文献
66.
67.
OBJECTIVE: To assess changes in response to nasal continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea syndrome (OSAS) concerning excessive daytime sleepiness (EDS), depressive state, and quality of life (QOL). PATIENTS AND METHODS: We assessed for EDS using the Epworth sleepiness scale (ESS), for mood using The Zung self-depression scale (SDS), and for QOL using Short-Form 36 (SF-36) in 132 patients with obstructive sleep apnea syndrome (OSAS) and control subjects. Patients had severe OSAS (apnea-hypopnea index, 59.4+/-23.8/h) and were more hypersomnolent and depressed, and had poorer QOL than 38 age- and gender-matched controls. RESULTS: Before treatment most QOL domains in the SF-36 were significantly associated with patients' SDS scores. With nasal CPAP, ESS and SDS scores were respectively decreased from 9.7+/-4.5 to 4.0+/-2.4 (p<0.0001) and from 49.2+/-10.4 to 45.1+/-9.6 (p<0.0005). Total SF-36 score and scores for seven of eight domains were increased significantly with treatment. Thus, nasal CPAP lessens EDS and depression, and improves QOL, in patients with severe OSAS. Further, magnitudes of changes in total SF-36 scores and in five of eight domains correlated significantly with magnitude of change in SDS score upon nasal CPAP treatment. No relationship was evident between treatment-associated score changes in SF-36 domains and ESS score change. CONCLUSION: Although patients with severe OSAS have poorer QOL than control subjects, nasal CPAP appears to improve QOL by alleviating depression. 相似文献
68.
Yuko Kitagawa Hitoshi Idani Haruhiro Inoue Harushi Udagawa Ichiro Uyama Harushi Osugi Natsuya Katada Hiroya Takeuchi Yasunori Akutsu Shinya Asami Ken Ishikawa Akihiko Okamura Taiki Ono Fumihiko Kato Toshiki Kawabata Koichi Suda Tomoko Takesue Tsuyoshi Tanaka Mai Tsutsui Kei Hosoda Satoru Matsuda Tatsuo Matsuda Mariko Mani Tatsuya Miyazaki 《Asian journal of endoscopic surgery》2015,8(2):114-124
69.