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41.
Anne Raben PhD Pia Siig Vestentoft PhD Jennie Brand-Miller PhD Elli Jalo MSc Mathjis Drummen PhD Liz Simpson PhD J. Alfredo Martinez PhD Teodora Handjieva-Darlenska PhD Gareth Stratton PhD Maija Huttunen-Lenz PhD Tony Lam MBA Jouko Sundvall MSc Roslyn Muirhead PhD Sally Poppitt PhD Christian Ritz PhD Kirsi H. Pietiläinen PhD Margriet Westerterp-Plantenga PhD Moira A. Taylor PhD Santiago Navas-Carretero PhD Svetoslav Handjiev PhD Melitta A. McNarry PhD Sylvia Hansen MSc Laura Råman BSc Shannon Brodie MSc Marta P. Silvestre PhD Tanja C. Adam PhD Ian A. Macdonald PhD Rodrigo San-Cristobal PhD Nadka Boyadjieva PhD Kelly A. Mackintosh PhD Wolfgang Schlicht PhD Amy Liu PhD Thomas M. Larsen PhD Mikael Fogelholm DSc 《Diabetes, obesity & metabolism》2021,23(2):324-337
42.
Lamminen H Niiranen S Niemi K Mattila H Kalli S 《Medical informatics and the Internet in medicine》2002,27(1):13-20
The primary objective of this study is to evaluate a sample of health-related services available on the internet. In addition, types of new services and service qualities that may be required in the future were estimated. A registered nurse using a questionnaire containing items about usability, quality, and other characteristics related to the subject carried out an evaluation of 100 health-related internet sites, and the results were processed to determine average qualities and graphical presentations for the studied parameters. The services studied differed greatly from each other both in terms of content and quality. A general observation was that sites of larger organizations were, typically, both in terms of presentation and content, more sophisticated than sites of smaller producers. A typical characteristic was the superficiality of the information presented. In conclusion, the internet is an emerging medium for health-related information, and standards for the production and presentation of health content for the internet are still in development. However, even at this early stage, the internet represents a valuable source of information for those in need of health-related information for both health care professionals and consumers. 相似文献
43.
Laura Hiltunen Jari Haukka Reija Ruuhela Kirsi Suominen Timo Partonen 《Environmental health and preventive medicine》2014,19(4):286-294
Objectives
Suicide peaks in late spring and October are still seen in Finland among many countries. Weather factors have been suggested as explanations for these peaks, although with inconsistent results. Since the exact timing of these peaks varies each year, the length of daylight and changes in it seem inadequate as an explanation. We hypothesized that ambient temperature and the timing of thermal seasons might associate with suicide rate.Methods
Suicide rates from three areas across Finland (N = 10,802) were analyzed with Poisson regression in six different models against variables calculated from the local ambient daily temperature, diurnal temperature range, and the duration from the onset of thermal seasons. Separate models for men and women were constructed.Results
The temperature change over 5 days associated with the suicide rate of men in Helsinki region, or in other words, the lower the suicide rate was, the higher the temperature decrease had been. For women, the results were more inconsistent.Conclusions
Our study is in line with some earlier studies which imply that impairment of thermoregulation might exist among suicide victims. 相似文献44.
Elina Koskela Kirsi Setälä Riku Kivisaari Juha Hernesniemi Aki Laakso 《Acta neurochirurgica》2014,156(7):1273-1279
Background
Visual field defects (VFDs) negatively affect activities of daily living and rehabilitation following aneurysmal subarachnoid haemorrhage (aSAH). The aim here was to assess VFDs in patients with aSAH and their associations with age, gender, aSAH severity, and clinical outcome.Methods
Patients admitted to Helsinki University Central Hospital and treated during 2011 were participants in this prospective study. Findings obtained with the Octopus 900 perimeter (Haag-Streit Inc, Koenic, Switzerland), the Goldmann perimeter (Haag-Streit Inc, Bern, Switzerland), or the confrontation visual field test on admission and 3 days, 14 days, 2 to 4 months, and 6 months postoperatively were assigned to 16 classes. Associations between post-chiasmal VFDs and relevant clinical, radiological, and demographic data were analysed with uni- and multivariate logistic regression.Results
Of 105 survivors at 6 months, 20 (19 %) had VFDs occurring for aneurysm- or operation-related reasons; homonymous hemianopias or quadrantanopias were the most common finding, occurring in 16 patients (15 %). Posterior ischaemic optic neuropathy presented in two patients (2 %). Ten survivors (10 %) no longer fulfilled visual field requirements for driving licences. Significant associations emerged between VFDs at 6 months and the Hunt and Hess (H&H), World Federation of Neurosurgical Societies (WFNS), and Fisher grades on admission, presence of intracerebral haemorrhage (ICH), hydrocephalus, or postoperative infarction, and higher modified Rankin Scale scores at 6 months. Multivariate logistic regression showed the H&H grade and presence of ICH to independently predict VFDs.Conclusions
Assessing VFDs is advisable, especially among patients with poor-grade aSAH (H&H grade IV or V) and ICH. 相似文献45.
THE ROLE OF PSYCHIATRIC,CARDIOMETABOLIC, AND MUSCULOSKELETAL COMORBIDITY IN THE RECURRENCE OF DEPRESSION‐RELATED WORK DISABILITY
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46.
Janne Orava Lauri Nummenmaa Tommi Noponen Tapio Viljanen Riitta Parkkola Pirjo Nuutila Kirsi A Virtanen 《Journal of cerebral blood flow and metabolism》2014,34(6):1018-1023
Brown adipose tissue (BAT) is able to generate heat and dissipate energy in response to cold exposure in mammals. It has recently been acknowledged that adult humans also have functional BAT, whose metabolic activity is reduced in obesity. In healthy humans, the cerebral mechanisms that putatively control BAT function are unclear. By using positron emission tomography (PET), we showed that cold-induced BAT activation is associated with glucose metabolism in the cerebellum, thalamus, and cingulate, temporoparietal, lateral frontal, and occipital cortices in lean participants, whereas no such associations were found under warm control conditions. The cold-induced increase in cerebral glucose metabolism was more robust in lean than obese participants. Cerebral glucose metabolism was not associated with skeletal muscle or white adipose tissue glucose uptake under warm or cold conditions. In conclusion, BAT metabolism was accompanied by the activation of specific cerebral regions, and this shows an uncharacterized role that the brain plays in the regulation of BAT function. In obese participants, the cold-induced response in cerebral activity was attenuated that provides a clue for obesity-induced impairment in BAT metabolism. 相似文献
47.
Anne‐Sofie Skou MD Heidi Glosli MD PhD Kirsi Jahnukainen MD PhD Marianne Jarfelt MD PhD Guemundur K. Jónmundsson MD Johan Malmros‐Svennilson MD PhD Karsten Nysom MD DMSc Henrik Hasle MD PhD On behalf of the Nordic Society of Pediatric Hematology Oncology 《Pediatric blood & cancer》2014,61(9):1638-1643
48.
Although there is a strong body of evidence showing that motivational factors are critical components of self‐regulated professional learning and commitment to work, little is known about nursing students' motivation regulation during their studies. The aim of this study was to gain a deeper understanding of nursing students' motivation regulation (MR) strategies and factors contributing to their reported use along their 3‐year study path in a blended learning environment. A purposeful sampling was used to select 12 undergraduate nursing students, who exhibited different MR profiles and had completed almost 3 years of study in a BL degree program. A qualitative, deductive, content analysis was used to depict students' experiences from their retrospective recollection in the interview situation. Seven motivation strategies were identified: environmental structuring, self‐consequating, goal‐oriented self‐talk, efficacy management, emotion regulation, regulation of value, and interest enhancement. Individual and situational factors were found to enhance and to sustain the use of appropriate MR strategies. The students exhibited versatility in their use of MR strategies, which were related to the study phase. These findings regarding nursing students' MR strategies should be considered in the development of nursing education programs and the implementation of improvements that contribute to professional and self‐regulated learning in BL programs. 相似文献
49.
Raija Auvinen Ritva Syrjnen Jukka Ollgren Hanna Nohynek Kirsi Skogberg 《Influenza and other respiratory viruses》2022,16(2):276
BackgroundThe clinical significance of respiratory syncytial virus (RSV) among adults remains underinvestigated. We compared the characteristics and population‐based attack rates of RSV and influenza hospitalizations.MethodsDuring 2018–2020, we recruited hospitalized adults with respiratory infection to our prospective substudy at a tertiary care hospital in Finland and compared the characteristics of RSV and influenza patients. In our retrospective substudy, we calculated the attack rates of all RSV and influenza hospitalizations among adults in the same geographic area during 2016–2020.ResultsOf the 537 prospective substudy patients, 31 (6%) had RSV, and 106 (20%) had influenza. Duration of hospitalization, need for intensive care or outcome did not differ significantly between RSV and influenza patients. RSV was more often missed or its diagnosis omitted from medical record (13% vs 1% p = 0.016 and 48% vs 15%, p > 0.001). In the retrospective substudy, the mean attack rates of RSV, influenza A, and influenza B hospitalizations rose with age from 4.1 (range by season 1.9–5.9), 15.4 (12.3–23.3), and 4.7 (0.5–16.2) per 100,000 persons among 18‐ to 64‐year‐olds to 58.3 (19.3–117.6), 204.1 (31.0–345.0), and 60.4 (0.0–231.0) per 100,000 persons among 65+‐year‐olds and varied considerably between seasons.DiscussionWhile the attack rates of influenza hospitalizations were higher compared with RSV, RSV and influenza hospitalizations were similar in severity. Missing or underreporting of RSV infections may lead to underestimating its disease burden. Both RSV and influenza caused a substantial amount of hospitalizations among the elderly, stressing the need for more effective interventions. 相似文献
50.
Monika Scheer Christian Vokuhl Iris Veit‐Friedrich Marc Münter Thekla von Kalle Michael Greulich Steffan Loff Sabine Stegmaier Monika Sparber‐Sauer Felix Niggli Ruth Ladenstein Bernarda Kazanowska Gustaf Ljungman Kirsi Jahnukainen Jrg Fuchs Stefan S. Bielack Ewa Koscielniak Thomas Klingebiel 《Pediatric blood & cancer》2020,67(2)