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31.
Hamed Kargozaran MD Vu Vu BS Partha Ray MD Sanjay Bagaria MD Shawn Steen MD Xing Ye MS Singh Gagandeep MD 《Annals of surgical oncology》2011,18(2):345-351
Background
The efficacy of surgery for invasive mucinous neoplasms is unclear. We examined the natural history of invasive mucinous cystic neoplasms (MCN) and invasive intraductal papillary mucinous neoplasms (IPMN) in patients who underwent pancreatic resection.Methods
The Surveillance, Epidemiology, and End Results (SEER) database (1996–2006) was queried for cases of resected invasive MCN and IPMN. Demographics, tumor characteristics, and overall survival were examined using log-rank analysis and multivariate Cox regression model.Results
Of 185 MCN cases and 641 IPMN cases, 73% and 48%, respectively, were women (P < 0.0001). Most (73%) IPMN were in the head of the pancreas; most (64%) MCN were in the tail/body (P < 0.0001). Lymph node metastasis was more common for IPMN than MCN (46% vs. 24%, P < 0.0001). Overall survival after resection was better for patients with stage I MCN vs. stage I IPMN (P = 0.0005), and it was better for patients with node-negative MCN vs. node-negative IPMN (P = 0.0061). There was no significant difference in survival of patients with stage IIA MCN vs. stage IIA IPMN (P = 0.5964), stage IIB MCN vs. stage IIB IPMN (P = 0.2262), or node-positive MCN vs. node-positive IPMN (P = 0.2263). Age older than 65 years (hazards ratio (HR) 1.71, P = 0.0046), high tumor grade (HR 2.68, P < 0.0001), higher T stage (HR 2.11, P < 0.0001), and IPMN histology (HR 1.90, P = 0.0040) predicted worse outcome in node-negative patients.Conclusions
Our findings suggest that survival is better after resection of invasive MCN versus invasive IPMN when disease is localized within the pancreas, but this difference disappears in the presence of nodal metastasis or extrapancreatic extension. 相似文献32.
Ljiljana Vlaški Dragan Dankuc Nada Vučković Vladimir Kljajić Danijela Dragičević Slobodanka Lemajić-Komazec 《Central European Journal of Medicine》2012,7(3):344-348
Aim
The aim of this paper is to present two case reports of patients with hemangiomas of the external auditory canal, and to overview all cases published in English language literature so far. 相似文献33.
Khanh vinh qu?c L??ng Lan Thi Hoàng Nguy?n 《World journal of gastroenterology : WJG》2012,18(38):5338-5350
Abnormal bone metabolism and dysfunction of the calcium-parathyroid hormone-vitamin D axis have been reported in patients with viral hepatitis. Some studies suggested a relationship between vitamin D and viral hepatitis. Genetic studies have provided an opportunity to identify the proteins that link vitamin D to the pathology of viral hepatitis (i.e., the major histocompatibility complex class Ⅱ molecules, the vitamin D receptor, cytochrome P 450 , the renin-angiotensin system, apolipoprotein E, liver X receptor, toll-like receptor, and the proteins regulated by the Sp1 promoter gene). Vitamin D also exerts its effects on viral hepatitis via non-genomic factors, i.e., matrix metalloproteinase, endothelial vascular growth factor, prostaglandins, cyclooxygenase-2, and oxidative stress. In conclusion, vitamin D could have a beneficial role in viral hepatitis. Calcitriol is best used for viral hepatitis because it is the active form of the vitamin D 3 metabolite. 相似文献
34.
Phan Vu Tra My Corinne Thompson Hoang Le Phuc Pham Thi Ngoc Tuyet Ha Vinh Nguyen Van Minh Hoang Pham Van Minh Nguyen Thanh Vinh Cao Thu Thuy Tran Thi Thu Nga Nguyen Thi Thu Hau James Campbell Nguyen Tran Chinh Tang Chi Thuong Ha Manh Tuan Jeremy Farrar Stephen Baker 《Emerging infectious diseases》2013,19(6):977-980
We performed a case–control investigation to identify risk factors for norovirus infections among children in Vietnam. Of samples from 1,419 children who had diarrhea and 609 who were asymptomatic, 20.6% and 2.8%, respectively, were norovirus positive. Risk factors included residential crowding and symptomatic contacts, indicating person-to-person transmission of norovirus. 相似文献
35.
36.
Nu Viet Vu Michelle L. Marcy Amber Barnhart Jerry A. Colliver Joseph Q. Henkle Kim Hodgson 《Teaching and learning in medicine》2013,25(4):255-259
The purpose of this study was to gather additional evidence pertinent to the construct validity of standardized patient‐based clinical performance examinations. Specifically, the study determined whether students who indicated they had previously read about, seen, or worked up a case on the examination performed differently on that case from those students who had not. Overall, it was found that students with previous reading or direct experiences with cases on the test tended to have higher case mean scores on those cases than those who had not. These results demonstrated that scores on standardized patient‐based performance examinations are sensitive to the examinees’ various learning experiences. 相似文献
37.
Nguyen Van Vinh Chau Nguyen Thi Thu Hong Nghiem My Ngoc Tran Tan Thanh Phan Nguyen Quoc Khanh Lam Anh Nguyet Le Nguyen Truc Nhu Nguyen Thi Han Ny Dinh Nguyen Huy Man Vu Thi Ty Hang Nguyen Thanh Phong Nguyen Thi Hong Que Pham Thi Tuyen Tran Nguyen Hoang Tu Tran Tinh Hien Ngo Ngoc Quang Minh Le Manh Hung Nguyen Thanh Truong Lam Minh Yen H. Rogier van Doorn Nguyen Thanh Dung Guy Thwaites Nguyen Tri Dung Le Van Tan for the OUCRU COVID- research group 《Emerging infectious diseases》2021,27(1):310
38.
Antaki F Tringali A Deprez P Kwan V Costamagna G Le Moine O Delhaye M Cremer M Devière J 《Gastrointestinal endoscopy》2008,67(1):163-168
BACKGROUND: Duodenal duplication cysts are rare congenital anomalies. Symptomatic cases have classically been treated by surgical resection, which can be complex because of the close proximity of the cysts to the papilla. OBJECTIVE: To describe a series of 8 patients with symptomatic duodenal duplication cysts who were treated endoscopically, with a special focus on the long-term outcome. DESIGN: Retrospective case series. SETTING: Three tertiary-care European academic hospitals. PATIENTS: Eight patients, age 8 to 72 years, were treated endoscopically for symptomatic intraluminal duodenal duplication cysts between 1981 and 2006. Seven patients presented with acute pancreatitis, and one patient presented with jaundice. INTERVENTION: Endoscopic incision and marsupialization of the cysts was performed by using a variety of endoscopic tools (needle-knife and regular sphincterotomes, cystotomes, and polypectomy snares). MAIN OUTCOME MEASUREMENTS: Technical success of endoscopic intervention and long-term clinical recurrence of symptoms. RESULTS: No major complications occurred. All patients remained asymptomatic at a median follow-up of 7.3 years. LIMITATIONS: Retrospective study; the small number of patients. CONCLUSIONS: The endoscopic treatment of symptomatic intraluminal duodenal duplication cysts is a safe and effective technique, with excellent long-term results. It represents a minimally invasive alternative to surgical resection and might be considered the preferred therapeutic modality for these cases. 相似文献
39.
Antibiotic therapy for inpatients with community‐acquired pneumonia in a developing country 下载免费PDF全文
40.