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Yuhki Koike Keiichi Uchida Mikihiro Inoue Kazuya Ohtsu Takaaki Tanaka Kohei Otake Koji Tanaka Masato Kusunoki 《Pediatrics international》2013,55(3):373-376
A case of sudden cardiopulmonary arrest in a 3‐month‐old girl is presented. The patient had barely recovered from hypoxic encephalopathy when she presented with repeated respiratory distress. Computed tomography and endoscopic analysis revealed a shiny polyp in the lateral wall of the nasopharynx, and this polyp was suspected to be the main cause of respiratory distress. After referral to our hospital, surgical removal was performed, and the histopathological diagnosis was hairy polyp. Hairy polyp is a rare congenital benign tumor that sometimes induces respiratory distress. This polyp can potentially induce a life‐threatening event. In a systematic review of 40 reported cases, polyps of ≤3.0 cm in diameter have a higher risk of respiratory distress than do those >3.0 cm in diameter (P = 0.01). Small hairy polyps may be lethal because of delayed diagnosis. To locate small hairy polyps, physicians should not hesitate to perform further examination because there is the possibility of oversight with only physical examination. 相似文献
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Sei‐ichiro Motegi Yoko Yokoyama Akihiko Uchiyama Sachiko Ogino Yuko Takeuchi Kazuya Yamada Tomoyasu Hattori Hiroaki Hashizume Yuichi Ishikawa Makoto Goto Osamu Ishikawa 《The Journal of dermatology》2014,41(12):1047-1052
Atypical progeroid syndrome (APS), including atypical Werner syndrome (AWS), is a progeroid syndrome involving heterozygous mutations in the LMNA gene encoding the nuclear protein lamin A/C. We report the first Japanese case of APS/AWS with a LMNA mutation (p.D300N). A 53‐year‐old Japanese man had a history of recurrent severe cardiovascular diseases as well as brain infarction and hemorrhages. Although our APS/AWS patient had overlapping features with Werner syndrome (WS), such as high‐pitched voice, scleroderma, lipoatrophy and atherosclerosis, several cardinal features of WS, including short stature, premature graying/alopecia, cataract, bird‐like face, flat feet, hyperkeratosis on the soles and diabetes mellitus, were absent. In immunofluorescence staining and electron microscopic analyses of the patient's cultured fibroblasts, abnormal nuclear morphology, an increase in small aggregation of heterochromatin and a decrease in interchromatin granules in nuclei of fibroblasts were observed, suggesting that abnormal nuclear morphology and chromatin disorganization may be associated with the pathogenesis of APS/AWS. 相似文献
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Shuichi Ota Toshihiro Matsukawa Satoshi Yamamoto Shinichi Ito Motohiro Shindo Kazuya Sato Takeshi Kondo Kyuhei Kohda Hajime Sakai Akio Mori Tohru Takahashi Hiroshi Ikeda Hiroyuki Kuroda Yoshihito Haseyama Masaki Yamamoto Takeo Sarashina Makoto Yoshida Ryoji Kobayashi Mitsufumi Nishio Toshimichi Ishihara Yasuo Hirayama Yasutaka Kakinoki Hajime Kobayashi Takashi Fukuhara Masahiro Imamura Mitsutoshi Kurosawa 《European journal of haematology》2018,101(1):95-105
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Effectiveness of electric toothbrushing in patients with neuromuscular disability: A randomized observer‐blind crossover trial 下载免费PDF全文
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Kotaro Shimizu Atsuhiko Uno Kazuya Takemura Naoki Ashida Ryohei Oya Takahiro Kitamura Yukinori Takenaka Yoshifumi Yamamoto 《Auris, nasus, larynx》2018,45(3):640-643
Laryngeal cleft is an anomaly of failed posterior closure of the larynx. Most cases are diagnosed and need treatment early in life due to respiratory and swallowing problems. We report an unusual case of a 66-year-old man with an asymptomatic laryngeal cleft until treatment for hypopharyngeal cancer. During concurrent chemoradiotherapy (CCRT), despite reduced tumor volume, he presented severe dysphagia and dyspnea, followed by severe pneumonia twice. Because CCRT had to be discontinued, a pharyngolaryngectomy was performed for the cancer treatment. The resected specimen showed total removal of the tumor and a total longitudinal cleft of the cricoid cartilage, classified as a type III laryngeal cleft by the Benjamin and Inglis’ classification. A review of computed tomography images indicated that the redundant mucosa from bilateral edges closed the separation of the posterior cricoid cartilage and narrowed the laryngeal airway during CCRT. Adult presentations of laryngeal cleft are quite rare with only ten reported cases in English literature; the present case is of the oldest patient. Undiagnosed cases with laryngeal cleft may exist asymptomatically or without severe symptoms. The awareness of this condition may increase its diagnosis as a cause of diseases such as aspiration and recurrent pneumonia even in adult patients. 相似文献
60.
Hirayama Y Hirasawa H Oda S Shiga H Nakanishi K Matsuda K Nakamura M Hirano T Moriguchi T Watanabe E Nitta M Abe R Nakada T 《Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy》2003,7(5):475-482
The aim of our study was to examine renal replacement therapies (RRT) that have been used for acute renal failure (ARF) in our intensive care unit (ICU) patients and to compare their outcomes. Sixteen patients who underwent intermittent hemodialysis (IHD), 14 patients who underwent continuous hemofiltration (CHF) in combination with IHD (CHF + IHD), and 38 patients who underwent continuous hemodiafiltration (CHDF) were evaluated. Regarding the effects of blood purification on hemodynamics and renal function, the percentage increase in blood pressure and percent rapid increase in urinary output were the greatest in the CHDF group. The hourly urinary output after the start of initial blood purification increased only in the CHDF group. The survival rate was significantly higher in the CHDF group. These results suggest that CHDF should be the first-line therapy for patients with ARF and that we are moving in the right direction regarding the application of RRT to treat ARF in ICU patients. 相似文献