全文获取类型
收费全文 | 928篇 |
免费 | 167篇 |
国内免费 | 18篇 |
专业分类
耳鼻咽喉 | 12篇 |
儿科学 | 48篇 |
妇产科学 | 9篇 |
基础医学 | 47篇 |
口腔科学 | 10篇 |
临床医学 | 158篇 |
内科学 | 237篇 |
皮肤病学 | 30篇 |
神经病学 | 47篇 |
特种医学 | 80篇 |
外科学 | 188篇 |
综合类 | 48篇 |
现状与发展 | 20篇 |
预防医学 | 62篇 |
眼科学 | 26篇 |
药学 | 29篇 |
中国医学 | 3篇 |
肿瘤学 | 59篇 |
出版年
2024年 | 7篇 |
2023年 | 42篇 |
2021年 | 18篇 |
2020年 | 23篇 |
2019年 | 10篇 |
2018年 | 50篇 |
2017年 | 44篇 |
2016年 | 32篇 |
2015年 | 40篇 |
2014年 | 40篇 |
2013年 | 60篇 |
2012年 | 22篇 |
2011年 | 32篇 |
2010年 | 48篇 |
2009年 | 64篇 |
2008年 | 38篇 |
2007年 | 26篇 |
2006年 | 32篇 |
2005年 | 17篇 |
2004年 | 15篇 |
2003年 | 18篇 |
2002年 | 14篇 |
2001年 | 18篇 |
2000年 | 11篇 |
1999年 | 19篇 |
1998年 | 29篇 |
1997年 | 33篇 |
1996年 | 44篇 |
1995年 | 29篇 |
1994年 | 18篇 |
1993年 | 21篇 |
1992年 | 7篇 |
1991年 | 9篇 |
1990年 | 10篇 |
1989年 | 12篇 |
1988年 | 15篇 |
1987年 | 15篇 |
1986年 | 12篇 |
1985年 | 13篇 |
1983年 | 6篇 |
1982年 | 9篇 |
1981年 | 5篇 |
1980年 | 5篇 |
1978年 | 13篇 |
1977年 | 10篇 |
1976年 | 8篇 |
1975年 | 7篇 |
1971年 | 4篇 |
1964年 | 5篇 |
1963年 | 4篇 |
排序方式: 共有1113条查询结果,搜索用时 15 毫秒
31.
David Adlam BA BM BCh DPhil Nicholas Evans MB BCh Aneil Malhotra MA MB BCh Disha Midha BCom/BSc BM Felicity Rowley BSc BM BCh David Hutchings MB ChB Mirae Shin BM BCh Guy Mole BSc Alexander Stockenhuber Mark Lumb BM BCh Jonathan Wordsworth MA MB BCh Sophie Frantal MSc J. Colin Forfar MD PhD FRCP 《Catheterization and cardiovascular interventions》2012,80(4):539-545
Objectives : To investigate rates of and reasons for second and subsequent stent procedures in an unselected, “real‐world” population. Background : Repeat stenting is the primary difference reported in clinical trials of alternative revascularization strategies. The incidence, indication, and outcome for repeat stenting in contemporary practice outside the more selective populations of trials and registries has not been described. Method : All patients undergoing a first percutaneous coronary intervention (PCI) procedure with stenting from January 2001 to August 2009 (10,509) from a large UK tertiary referral and district general hospital were identified. Mortality and the incidence, timing, and indication for repeat revascularization in this population were investigated from patient records. Results : Of 10,509 patients undergoing a first PCI and stent implant 23.5% underwent repeat angiography of which 11.2% required repeat PCI and 2% coronary artery bypass grafting (median follow‐up of 3.8 years). A total of 1.3% went on to a third PCI. The commonest indication for repeat stenting was disease progression remote from the original stent (46%) and planned staged PCI (23%); 21% had a stent‐related indication. Functional assessment before repeat stenting was used in one‐third of stable patients. Mortality was 2.5% per annum. Conclusions : In contemporary practice, patients undergoing a first stenting procedure have a low subsequent mortality, and the substantial majority (86.4%) requires no further revascularization over a median 3.8 year follow‐up. For those who do require repeat stenting, this is most commonly at a site remote from the first stent. © 2012 Wiley Periodicals, Inc. 相似文献
32.
33.
34.
35.
Kirsi Murtomäki MD Tuomas Mertsalmi MD Elina Jaakkola MD PhD Elina Mäkinen MD PhD Reeta Levo RN Tanja Nojonen RN Mikael Eklund BM Simo Nuuttila BM Kari Lindholm RN Eero Pekkonen MD PhD Juho Joutsa MD PhD Tommi Noponen PhD Toni Ihalainen PhD Valtteri Kaasinen MD PhD Filip Scheperjans MD PhD 《Movement disorders》2022,37(6):1284-1289
36.
Meredith Achey BM Jason L. Aldred MD Noha Aljehani MD Bastiaan R. Bloem MD PhD Kevin M. Biglan MD MPH Piu Chan MD PhD Esther Cubo MD PhD E. Ray Dorsey MD MBA Christopher G. Goetz MD Mark Guttman MD Anhar Hassan MB BCh FRACP Suketu M. Khandhar MD Zoltan Mari MD Meredith Spindler MD Caroline M. Tanner MD PhD Pieter van den Haak MSc Richard Walker MD Jayne R. Wilkinson MD 《Movement disorders》2014,29(7):871-883
Travel distance, growing disability, and uneven distribution of doctors limit access to care for most Parkinson's disease (PD) patients worldwide. Telemedicine, the use of telecommunications technology to deliver care at a distance, can help overcome these barriers. In this report, we describe the past, present, and likely future applications of telemedicine to PD. Historically, telemedicine has relied on expensive equipment to connect single patients to a specialist in pilot programs in wealthy nations. As the cost of video conferencing has plummeted, these efforts have expanded in scale and scope, now reaching larger parts of the world and extending the focus from care to training of remote providers. Policy, especially limited reimbursement, currently hinders the growth and adoption of these new care models. As these policies change and technology advances and spreads, the following will likely develop: integrated care networks that connect patients to a wide range of providers; education programs that support patients and health care providers; and new research applications that include remote monitoring and remote visits. Together, these developments will enable more individuals with PD to connect to care, increase access to expertise for patients and providers, and allow more‐extensive, less‐expensive participation in research. © 2014 International Parkinson and Movement Disorder Society 相似文献
37.
38.
Brian C. Case MD Sant Kumar BA Charan Yerasi MD Brian J. Forrestal MBBS Anees Musallam MD Chava Chezar-Azerrad MD Nauman Khalid MD Evan Shlofmitz DO Yuefeng Chen MD PhD Jaffar M. Khan BM BCh PhD Lowell F. Satler MD Itsik Ben-Dor MD Hayder Hashim MD Nelson L. Bernardo MD Toby Rogers MD PhD Ron Waksman MD 《Catheterization and cardiovascular interventions》2021,98(3):572-577
39.
Jaffar M. Khan BM BCh Robert J. Lederman MD 《Catheterization and cardiovascular interventions》2018,91(6):1052-1053
- Transcatheter electrosurgery has emerging value in a range of other new procedures that require traversing tissue (transcaval access, transcatheter Glenn Shunt) or slicing tissue (LAMPOON slicing of the mitral valve and BASILICA slicing of the aortic valve).
- This is the first report of bipolar radiofrequency wires used to cross lesions in humans, reported here in seven re‐entry CTO cases.
- The bipolar configuration may provide directionality to charge without need for wire alignment and advancement, but is theoretically disadvantageous for tissue “cutting” because of problems with charge concentration.
40.
A study was conducted on the phosphorylation of proteins in the neutrophil cytosol in response to phorbol myristate acetate (PMA) and N- formyl-methionyl-leucyl-phenylalanine (fMLP). Autoradiography of gel electrophoretograms prepared from neutrophils incubated with 32Pi in the presence and absence of the activators showed nine proteins whose state of phosphorylation was affected by neutrophil activation. 32P was gained by eight of these proteins and was lost by the ninth. For all but one of these proteins, the change in the extent of labeling appeared to reach completion by one to two minutes. It was possible to quantitate the changes in 32P content of three of the nine proteins. One of these was the 20-kD protein that lost label when the neutrophils were activated. Quantitation showed that over half the 32P present in this protein in the resting state was gone within 0.2 minutes after activation. The other two were proteins weighing 11 and 69 kD. The phosphorylation characteristics of these two proteins differed, depending on whether activation had been carried out with PMA or fMLP. These differences in protein phosphorylation support other evidence suggesting that PMA and fMLP do not activate neutrophils by identical biochemical pathways. Differences in phosphorylation between resting and activated cells were not affected by dibutyryl cyclic guanosine monophosphate (cGMP), dibutyryl cyclic adenosine monophosphate (cAMP), theophylline, aspirin, hydrocortisone, or colchicine. The differences were abolished, however, by 30 mumol/L trifluoperazine. This finding is consistent with the hypothesis that the calcium/calmodulin system plays a biochemical role in the activation of neutrophils. 相似文献