全文获取类型
收费全文 | 2494篇 |
免费 | 119篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 30篇 |
儿科学 | 42篇 |
妇产科学 | 7篇 |
基础医学 | 386篇 |
口腔科学 | 69篇 |
临床医学 | 209篇 |
内科学 | 573篇 |
皮肤病学 | 38篇 |
神经病学 | 243篇 |
特种医学 | 79篇 |
外科学 | 273篇 |
综合类 | 1篇 |
预防医学 | 93篇 |
眼科学 | 55篇 |
药学 | 181篇 |
中国医学 | 10篇 |
肿瘤学 | 334篇 |
出版年
2022年 | 30篇 |
2021年 | 58篇 |
2020年 | 26篇 |
2019年 | 37篇 |
2018年 | 53篇 |
2017年 | 50篇 |
2016年 | 52篇 |
2015年 | 44篇 |
2014年 | 59篇 |
2013年 | 81篇 |
2012年 | 135篇 |
2011年 | 154篇 |
2010年 | 76篇 |
2009年 | 86篇 |
2008年 | 125篇 |
2007年 | 133篇 |
2006年 | 124篇 |
2005年 | 146篇 |
2004年 | 131篇 |
2003年 | 121篇 |
2002年 | 133篇 |
2001年 | 56篇 |
2000年 | 63篇 |
1999年 | 62篇 |
1998年 | 36篇 |
1997年 | 42篇 |
1996年 | 39篇 |
1995年 | 26篇 |
1994年 | 31篇 |
1993年 | 21篇 |
1992年 | 34篇 |
1991年 | 32篇 |
1990年 | 22篇 |
1989年 | 23篇 |
1988年 | 37篇 |
1987年 | 26篇 |
1986年 | 15篇 |
1985年 | 38篇 |
1984年 | 9篇 |
1983年 | 13篇 |
1982年 | 10篇 |
1981年 | 15篇 |
1980年 | 8篇 |
1979年 | 8篇 |
1977年 | 7篇 |
1974年 | 8篇 |
1972年 | 12篇 |
1971年 | 13篇 |
1970年 | 7篇 |
1969年 | 12篇 |
排序方式: 共有2623条查询结果,搜索用时 15 毫秒
1.
Kimihiro Shimizu Yoshimi Otani Takashi Ibe Osamu Kawashima Mituhiro Kamiyoshihara Yasuo Morishita 《General thoracic and cardiovascular surgery》2005,53(1):39-41
Late-onset chylothorax occurred 49 days after right lower lobectomy for lung cancer in a 76-year-old man. Chylothorax was successfully managed by conservative treatment with chest tube drainage and an enteral low-fat diet. Chylothorax may occur in the late period after pulmonary resection and systematic mediastinal lymph node dissection for lung cancer, for which conservative management is the treatment of choice. 相似文献
2.
3.
4.
L Sumitra Hada Nobuko Kakiuchi Masao Hattori Tsuneo Namba 《Phytotherapy research : PTR》1989,3(4):140-144
During the course of our studies on dental caries prevention by traditional medicines, fatty acids (myristic and oleic acids etc.) and procyanidins from betel nuts (the seed of Areca catechu L.) were respectively revealed to be the major antibacterial principles against a primary cariogenic bacterium, Streptococcus mutans, and the major inhibitory principles against glucosyltransferase from S. mutans. 相似文献
5.
Yasuhiko Tamada Kikuka Yokochi Yoshimi Oshitani Yukiko Nitta Toshihiko Ikeya Kazuo Hara Katsushi Owaribe 《The Journal of dermatology》1995,22(3):201-204
We report a 73-year-old woman with typical clinical, histological and immunofluorescence features of pemphigoid nodularis. Direct immunofluorescence studies of prurigo nodularis-like lesions and peribullous skin showed the linear deposition of IgG and C3 at the basement membrane zone. Circulating IgG against the basement membrane was also detected by indirect immunofluorescence. The serum from the patient was shown to contain the autoantibody against 230 kDa hemidesmosomal antigen associated with bullous pemphigoid antigen. 相似文献
6.
K Morikawa M Kakiuchi M Fukuoka H Kato Y Ito Y Gomi 《Japanese journal of pharmacology》1990,52(3):405-411
We evaluated the effects of various intravenously administered drugs, which had been shown to influence bladder function in anesthetized and/or conscious rats, on the cystometrogram in conscious restrained-denervated rats (produced by transection of the hypogastric nerve) placed in a restraining cage in comparison to those in conscious restrained-intact rats (with the hypogastric nerve intact) placed in a restraining cage. The bladder capacity in the restrained-denervated rats was smaller than that in restrained-intact rats and did not change when they were transferred to a wide cage, but the bladder capacity of the restrained-intact rats decreased following transfer to the wide cage. Therefore, the activity of the hypogastric nerve in conscious rats appears to be stimulated by restraint. Atropine suppressed the amplitude of the micturition contraction (time to micturition in the cystometrogram). In the restrained-denervated rats, thiopental and indomethacin increased the bladder capacity at almost the same doses as those in restrained-intact rats, but it took a higher dose of morphine to increase the bladder capacity than in restrained-intact rats. These findings suggest that cystometrography in restrained-denervated rats is a useful method for evaluating the effect of a newly developed agent on bladder function without any influence from the hypogastric nerve. 相似文献
7.
Shigeharu Kimura Yoshimi Ohshige Liping Lin Tadashi Okumura Chizuko Yanaihara Noboru Yanaihara† Yahe Shiotani 《Journal of neuroendocrinology》1994,6(5):503-507
The localization of pituitary adenylate cyclase-activating polypeptide (PACAP) in the hypothalamus-pituitary system in rats was examined in light and electron microscopic immunocytochemistry using a specific antiserum to synthetic PACAP 1–38 (R0831). In light microscopic study, intensely PACAP-immunostained perikarya were observed in the supraoptic and paraventricular magnocellular nucleus in the hypothalamus. In the median eminence, many immunoreactive nerve fibers were observed in the internal layer, but a few immunoreactive terminals were noticed in the external layer. In the pituitary gland, numerous immunoreactive nerve fibers were observed in the posterior lobe. In the intermediate lobe, moderately immunostained cells were observed, but in the anterior lobe no immunostained cells were noticed. In electron microscopic study, PACAP-immunoreactivity was examined by avidin-biotin peroxidase complex method. In the perikarya of the supraoptic and paraventricular magnocellular nucleus, DAB-reaction products were distributed diffusely in the cytoplasmic matrix, frequently attaching to the rough-surfaced endoplasmic reticulum. In the nerve terminals of the posterior lobe, reaction products were observed among the secretory granules, but sometimes upon them. In the cells of the intermediate lobe, reaction products were also distributed in the cytoplasmic matrix. 相似文献
8.
Kenji Yoshimi Masatoshi Takeda Tsuyoshi Nishimura Takashi Kudo Yu Nakamura Kunitoshi Tada Nobuyoshi Iwata 《Brain research》1991,560(1-2):149-158
Changes in MAP2 and clathrin immunoreactivity were studied in gerbil hippocampus after transient cerebral ischemia. MAP2 immuno-reactivity decreased significantly by 1 h in the subiculum-CA1 and CA2 areas which correspond to reactive change, while no decrease was observed in CA1 until day 4. Before the initiation of delayed neuronal death, MAP2 immunoreactivity was not changed in CA1. On the other hand clathrin immunoreactivity increased in the pyramidal cell layer of CA1 by 3 h after ischemia and remained high for 2 days. Clathrin immunoreactivity in the pyramidal cell layer of CA1 diminished after delayed neuronal death. The transient change of clathrin was noted especially in CA1 in the period prior to delayed neuronal death. These results imply an abnormal change in clathrin turnover after ischemia, which may participate in the pathogenesis of delayed neuronal death. 相似文献
9.
Sugie Shigeyuki; Yoshimi Naoki; Tanaka Takuji; Mori Hideki; Williams Gary M. 《Carcinogenesis》1994,15(1):95-98
The nuclear pore density and area were measured on freeze-fracturednuclei of ACI/N rat liver altered foci, adenomas and carcinomasinduced by 2-acetylaminofluorene, and compared with those ofnormal hepatocytes. The pore density of nuclei from these preneoplasticand neoplastic lesions was significantly higher than that ofhepatocytes, but there was no difference between lesions. Thearea of nuclear pores of the focus cells did not differ fromnormal hepatocytes, whereas the areas of pores of adenoma andcarcinoma cells were increased. Moreover, the nuclear pore areaof carcinomas was significantly greater than that of adenomas.These results suggest that some changes may occur in nuclearpores in the progress of tumorigenesis. 相似文献
10.
Masaki Shinoda Tsuyoshi Yamaguchi Yoshimi Tanaka Osamu Sato Sin Kobayashi Yutaka Suzuki 《Child's nervous system》1992,8(4):219-221
Single photon emission computerized tomography (SPECT) is now widely used as one of the tools in evaluating cerebral blood flow (CBF). The authors report the CBF changes in childhood hydrocephalus. Five pediatric cases studied by 123I-IM SPECT in children are presented. The authors counted radioactivities both in early and delayed images in each patient, and calculated the reabsorption ratio (RR). Two negative-RR cases and three positive-RR cases were found. All of the negative-RR patients had a poor prognosis, while all of the positive-RR patients had a favorable outcome. 相似文献