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41.
Juliana Azevedo de Meneses Liana de Araújo Trugilho Samantha de Aguiar Lima Amanda Carneiro Ferreira Freitas Henrique Saldanha Melo Maitê Rocha Ferreira 《The journal of maternal-fetal & neonatal medicine》2019,32(9):1516-1522
Objective: This study aimed to investigate a flaxseed diet during different developmental periods, and its effect on the blood pressure of rats submitted to stress.Methods: Fifty-six male rats (F1), born from 14 rats (F0), were divided into seven groups (n?=?8): flaxseed group (FG); flaxseed group gestation and lactation (FG-GL); flaxseed group weaning (FG-W); flaxseed group weaning and stress (FG-WS); flaxseed group stress (FG-S); flaxseed group gestation lactation and weaning (FG-GLW), and control Group (CG). Stress protocol was undertaken for 1 month. Blood pressure was analysed before and after the stress protocol. The left adrenal glands and serum corticosterone levels were analysed.Results: Systolic blood pressure before stress was lower in all groups with flaxseed diet compared with the CG (p?=?.00001). After stress, CG showed higher blood pressure compared with FG, FG-GL, and FG-GLW (p?=?.004). The levels of corticosterone were lower in the FG between all groups (p?.000001) and the CG showed higher compared with FG-W, FG-WS, FG-GL, and FG-GLW (p?.0001). The adrenal gland did not show differences.Conclusions: Results suggest a possible factor from a flaxseed diet against the effects of stress on a blood pressure in all periods of life but especially in the gestation and lactation periods. 相似文献
42.
Fernanda Neves de Carvalho Carolina Toniolo Zenatti Danila Cassia Reis Santana Juliana Maria da Silva Juliane Cristina Oliveira dos As Katia Kisielow dos Anjos Jessica Sigari Cassia de Lima Santos Marcelle Guerra Olivia Pereira Barros Tomaz Cochemore Roberto Camargo Narciso Mario Lucio Baptista Filho 《The Brazilian journal of infectious diseases》2018
43.
Andrew J. Muzyk Emily Peedin Juliana Lipetzky Haley Parker Mark P. McEachern Kelan Thomas 《Substance Abuse》2017,38(4):455-463
Background: The authors sought to systematically review the quantity and quality of literature describing substance use disorders (SUDs) education in US schools of pharmacy and determine the effectiveness of the educational interventions employed. Methods: The authors conducted a systematic review of SUDs education studies in US pharmacy schools. All literature database searches were performed on April 30, 2016, in 5 databases: Ovid MEDLINE, Ovid MEDLINE In-Process & Other Non-Indexed Citations, Embase.com, ERIC via FirstSearch, and CINAHL via EBSCOhost. The study authors conducted this systematic review according to the Preferred Reporting Items for Systemic Reviews and Meta-analyses guidelines and registered it with PROSPERO, which is an international prospective register of systematic reviews. The PROSPERO registration number is CRD42016037443. The study authors created a modified data extraction sheet based on the Best Evidence in Medical Education coding sheet. A Medical Education Research Study Quality Instrument (MERSQI) score was calculated for included articles. Results: From the 1626 retrieved records, 7 were included in the present review. The studies assessed students’ impressions and abilities regarding SUDs pre- and post-intervention. The mean ± SD MERSQI score of the 7 studies was 9.86 ± 1.21 (range: 8–11.5). The included articles assessed pharmacy students at various academic years, with the majority students in either their first or second year of pharmacy school, and described both required and elective courses. The educational interventions varied in design and outcomes measured. Education included nicotine, alcoholism, and SUDs in general. None of the included articles reported on education regarding opioid use disorders. Conclusions: The studies included in this systematic review demonstrate that teaching pharmacy students about SUDs produces a positive impact in their attitudes and knowledge on this subject. 相似文献
44.
Soares Mayara Sandrielly Pereira Viau Cassiana Macagnan Saffi Jenifer Costa Marcelo Zanusso da Silva Tatiane Morgana Oliveira Pathise Souto Azambuja Juliana Hofstatter Barschak Alethéa Gatto Braganhol Elizandra S Wyse Angela T Spanevello Roselia Maria Stefanello Francieli Moro 《Metabolic brain disease》2017,32(5):1693-1703
Metabolic Brain Disease - High plasma levels of methionine (Met) and its metabolites such as methionine sulfoxide (MetO) may occur in several genetic abnormalities. Patients with hypermethioninemia... 相似文献
45.
Juliana Medeiros de Moraes Diego Eterno de Oliveira Mendonça Vânia Beatriz L. Moura Milton Adriano Pelli Oliveira Cristina Lopes Afonso Marina Clare Vinaud Maria Márcia Bachion Ruy de Souza Lino Jr. 《Lasers in medical science》2013,28(4):1169-1176
Third-degree burn wounds are considered severe injuries because they destroy all the skin layers and may affect subcutaneous tissues, fasciae, muscles, and bones. To favor the healing process of the injured tissues, it is very useful to diminish the occurrence of the inflammatory process. The present study was aimed at comparing the effect of different energetic densities of AlGaInP laser on the inflammatory process and in the healing of third-degree burn wounds in Wistar rats. This study was approved by the Ethics Committee, in which 36 adult male rats were selected and suffered the induction of third-degree burn injury. These rats were divided as follows: group 1—control (treated with silver sulfadiazine), group 2—received energy density of 3 J/cm2, and group 3—received energy density of 6 J/cm2. All animals daily received an occlusive bandage with silver sulfadiazine and 8 % papain. The laser therapy was performed alternatively three times a week. The animals were evaluated on the 3rd, 7th, 14th, and 21st days after the initial lesion and euthanized for the macroscopic, histologic, and morphometric analysis. A higher production of collagen was observed at 7 days and a greater re-epithelialization at 21 days in group 3 (6 J/cm2). Furthermore, the latter when compared to the other groups presented macroscopically a better aspect of the scar at 21 days with more granulation tissue and fibrosis. We conclude that the AlGaInP laser used in dosages of 3 and 6 J/cm2 favors the healing of third-degree burn wounds induced in rats. 相似文献
46.
Juliana Moscardini Chavasco Bárbara Helena Muniz Prado E Feliphe Claudio Daniel Cerdeira Fabrício Damasceno Leandro Luiz Felipe Leomil Coelho Jéferson Junior da Silva Jorge Kleber Chavasco Amanda Latercia Tranches Dias 《Revista do Instituto de Medicina Tropical de S?o Paulo》2014,56(1):13-20
The antimicrobial activity of plant hidroethanolic extracts on bacteria
Gram positive, Gram negative, yeasts, Mycobacterium tuberculosis H37
and Mycobacterium bovis was evaluated by using the technique of Agar
diffusion and microdilution in broth. Among the extracts evaluated by Agar diffusion,
the extract of Bidens pilosa leaf presented the most expressive
average of haloes of growth inhibition to the microorganisms, followed by the extract
of B. pilosa flower, of Eugenia pyriformis'' leaf
and seed, of Plinia cauliflora leaf which statistically presented
the same average of haloes inhibitory formation on bacteria Gram positive, Gram
negative and yeasts. The extracts of Heliconia rostrata did not
present activity. Mycobacterium tuberculosis H37 and
Mycobacterium bovis (BCG) appeared resistant to all the extracts.
The susceptibility profile of Candida albicans and
Saccharomyces cerevisiae fungi were compared to one another and
to the Gram positive Bacillus subtilis, Enterococcus
faecalis and the Gram negative Salmonella typhimurium
bacteria (p > 0.05). The evaluation of cytotoxicity was carried
out on C6-36 larvae cells of the Aedes albopictus mosquito. The
extracts of stem and flower of Heliconia rostrata, leaf and stem of
Plinia cauliflora, seed of Anonna crassiflora
and stem, flower and root of B. pilosa did not present toxicity in
the analyzed concentrations. The highest rates of selectivity appeared in the
extracts of stem of A. crassiflora and flower of B.
pilosa to Staphylococcus aureus, presenting potential
for future studies about a new drug development. 相似文献
47.
Characterization of four Latin American families confirms previous findings and reveals novel features of acid‐labile subunit deficiency 下载免费PDF全文
Paula A. Scaglia Ana C. Keselman Débora Braslavsky Lucía C. Martucci Liliana M. Karabatas Sabina Domené Mariana L. Gutiérrez María G. Ballerini María G. Ropelato Angela Spinola‐Castro Adriana A. Siviero‐Miachon Juliana Saito Tartuci María Sol Rodríguez Azrak Rodolfo A. Rey Héctor G. Jasper Ignacio Bergadá Horacio M. Domené 《Clinical endocrinology》2017,87(3):300-311
48.
Tôrres Luísa Helena do Nascimento Silva Débora Dias da Neri Anita Liberalesso Hilgert Juliana Balbinot Hugo Fernando Neves Sousa Maria da Luz Rosário de 《Nutrition (Burbank, Los Angeles County, Calif.)》2013,29(1):152-157
ObjectivePoor oral status, represented by partial/complete tooth loss, may lead to changes in food choice, which may ultimately lead to underweight, overweight, or obesity. The aim of this study is to evaluate whether poor oral status is associated with underweight or overweight/obesity, regardless of physical activity.MethodsThis cross-sectional study is part of a major project, The Frailty in Brazilian Elderly Study, carried out in Campinas, Brazil (2008–2009). The sample was composed of 900 independent-living older adults. Complete data were available for 875 individuals including sociodemographic, self-reported amount of medications used and eating difficulty questionnaire, smoking habit, depressive symptoms, physical activity, oral examination, and anthropometric assessments according to the WHO criteria. Body mass index was used as an outcome. Multinomial logistic regression was adjusted for confounding variables.ResultsThe mean age of the sample was 72.7 y (±5.81) and the prevalence of edentulism was 47.7%. Edentate individuals not wearing dentures were more likely to be underweight [odds ratio (OR) = 3.94, 95% confidence interval (CI) 1.14–13.64] and overweight/obese (OR = 2.88, 95%CI 1.12–7.40). Males (OR = 0.56, 95%CI 0.36–0.85) and those not using medications (OR = 0.41 95%CI 0.24–0.70) were less likely to be overweight/obese. Individuals who smoke (OR = 2.62, 95%CI 1.26–5.44) were more likely to be underweight. Older individuals with family income between 3.1 and 5 minimum wage (OR = 1.69, 95%CI 1.00–2.87) were more likely to be overweight/obese.ConclusionTo our knowledge, this is one of the first studies associating poor oral health, represented by edentulism not rehabilitated with dentures, with unfavorable body mass, regardless of the two major confounders, physical activity and depression symptoms. 相似文献
49.
50.
Ariana Ferrari Aline Martins de Carvalho Josiane Steluti Juliana Teixeira Dirce Maria Lobo Marchioni Samuel Aguiar Jr. 《Nutrients》2015,7(6):4318-4335
To assess the ingestion of folate and nutrients involved in the 1-carbon cycle in non-treated patients with colorectal adenocarcinoma in a reference center for oncology in southeastern Brazil. In total, 195 new cases with colorectal adenocarcinoma completed a clinical evaluation questionnaire and a Food Frequency Questionnaire (FFQ). Blood samples from 161 patients were drawn for the assessment of serum folate. A moderate correlation was found between serum concentrations of folate, folate intake and the dietary folate equivalent (DFE) of synthetic supplements. Mulatto or black male patients with a primary educational level had a higher intake of dietary folate. Of patients obtaining folate from the diet alone or from dietary supplements, 11.00% and 0.10%, respectively, had intake below the recommended level. Of the patients using dietary supplements, 35% to 50% showed high levels of folic acid intake. There was a prevalence of inadequacy for vitamins B2, B6 and B12, ranging from 12.10% to 20.18%, while 13.76% to 22.55% of patients were likely to have adequate choline intake. The considerable percentage of patients with folate intake above the recommended levels deserves attention because of the harmful effects that this nutrient may have in the presence of established neoplastic lesions. 相似文献