全文获取类型
收费全文 | 190368篇 |
免费 | 11542篇 |
国内免费 | 480篇 |
专业分类
耳鼻咽喉 | 2483篇 |
儿科学 | 6152篇 |
妇产科学 | 3963篇 |
基础医学 | 25775篇 |
口腔科学 | 8128篇 |
临床医学 | 13936篇 |
内科学 | 43367篇 |
皮肤病学 | 4800篇 |
神经病学 | 16065篇 |
特种医学 | 5776篇 |
外国民族医学 | 26篇 |
外科学 | 23868篇 |
综合类 | 1514篇 |
现状与发展 | 1篇 |
一般理论 | 68篇 |
预防医学 | 19100篇 |
眼科学 | 3839篇 |
药学 | 11371篇 |
中国医学 | 760篇 |
肿瘤学 | 11398篇 |
出版年
2023年 | 946篇 |
2022年 | 1631篇 |
2021年 | 4260篇 |
2020年 | 2776篇 |
2019年 | 3971篇 |
2018年 | 5500篇 |
2017年 | 4041篇 |
2016年 | 3827篇 |
2015年 | 4524篇 |
2014年 | 6116篇 |
2013年 | 7796篇 |
2012年 | 12154篇 |
2011年 | 12755篇 |
2010年 | 6513篇 |
2009年 | 5883篇 |
2008年 | 9982篇 |
2007年 | 10619篇 |
2006年 | 9942篇 |
2005年 | 10098篇 |
2004年 | 9383篇 |
2003年 | 8686篇 |
2002年 | 6673篇 |
2001年 | 5242篇 |
2000年 | 5248篇 |
1999年 | 4627篇 |
1998年 | 1717篇 |
1997年 | 1423篇 |
1996年 | 1418篇 |
1995年 | 1213篇 |
1994年 | 1205篇 |
1993年 | 1071篇 |
1992年 | 2774篇 |
1991年 | 2680篇 |
1990年 | 2430篇 |
1989年 | 2420篇 |
1988年 | 2183篇 |
1987年 | 2043篇 |
1986年 | 1906篇 |
1985年 | 1818篇 |
1984年 | 1324篇 |
1983年 | 1066篇 |
1982年 | 613篇 |
1981年 | 573篇 |
1980年 | 521篇 |
1979年 | 965篇 |
1978年 | 646篇 |
1977年 | 517篇 |
1975年 | 568篇 |
1974年 | 564篇 |
1973年 | 573篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
22.
Qiaojie Wang Karan Goswami Noam Shohat Arash Aalirezaie Jorge Manrique Javad Parvizi 《The Journal of arthroplasty》2019,34(5):947-953
Background
Whether prolonged operative time is an independent risk factor for subsequent surgical site infection (SSI) and periprosthetic joint infection (PJI) following total joint arthroplasty (TJA) remains a clinically significant and underexplored issue. The aim of this study is to investigate the association between operative time and the risk of subsequent SSI and PJI in patients undergoing primary TJA.Methods
We retrospectively reviewed 17,342 primary unilateral total knee arthroplasty and total hip arthroplasty performed at a single institution between 2005 and 2016, with a minimum follow-up of 1 year. A multivariate logistic regression model was conducted to identify the association between operative time and the development of SSI within 90 days and PJI within 1 year.Results
Overall, the incidence of 90-day SSI and 1-year PJI was 1.2% and 0.8%, respectively. Patients with an operative time of >90 minutes had a significantly higher incidence of SSI and PJI (2.1% and 1.4%, respectively) compared to cases lasting between 60 and 90 minutes (1.1% and 0.7%), and those lasting ≤60 minutes (0.9% and 0.7%, P < .01). In the multivariate model, the risk for infection increased by an odds ratio of 1.346 (95% confidential interval 1.114-1.627) for 90-day SSI and 1.253 (95% confidential interval 1.060-1.481) for 1-year PJI for each 20-minute increase in operative time.Conclusion
In patients undergoing primary TJA, each 20-minute increase in operative time was associated with nearly a 25% increased risk of subsequent PJI. We advocate that surgeons pay close attention to this underappreciated risk factor while maintaining safe operative practices, which minimize unnecessary steps and wasted time in the operating room. 相似文献23.
24.
25.
26.
27.
28.
R.D. Olmos R.C. de Figueiredo E.M. Aquino P.A. Lotufo I.M. Bensenor 《Brazilian journal of medical and biological research》2015,48(8):751-758
Thyroid diseases are common, and use of levothyroxine is increasing worldwide. We
investigated the influence of gender, race and socioeconomic status on the diagnosis
and treatment of thyroid disorders using data from the Brazilian Longitudinal Study
of Adult Health (ELSA-Brasil), a multicenter cohort study of civil servants (35-74
years of age) from six Brazilian cities. Diagnosis of thyroid dysfunction was by
thyrotropin (TSH), and free thyroxine (FT4) if TSH was altered, and the use of
specific medications. Multivariate logistic regression models were constructed using
overt hyperthyroidism/hypothyroidism and levothyroxine use as dependent variables and
sociodemographic characteristics as independent variables. The frequencies of overt
hyper- and hypothyroidism were 0.7 and 7.4%, respectively. Using whites as the
reference ethnicity, brown, and black race were protective for overt hypothyroidism
(OR=0.76, 95%CI=0.64-0.89, and OR=0.53, 95%CI=0.43-0.67, respectively, and black race
was associated with overt hyperthyroidism (OR=1.82, 95%CI=1.06-3.11). Frequency of
hypothyroidism treatment was higher in women, browns, highly educated participants
and those with high net family incomes. After multivariate adjustment, levothyroxine
use was associated with female gender (OR=6.06, 95%CI=3.19-11.49) and high net family
income (OR=3.23, 95%CI=1.02-10.23). Frequency of hyperthyroidism treatment was higher
in older than in younger individuals. Sociodemographic factors strongly influenced
the diagnosis and treatment of thyroid disorders, including the use of
levothyroxine. 相似文献
29.
Maria Gonzalez-Cao Cristina Carrera Juan Francisco Rodriguez Moreno Pedro Rodríguez-Jiménez Mónica Antoñanzas Basa Rosa Feltes Ochoa Teresa Puertolas Eva Muñoz-Couselo José Luis Manzano Ivan Marquez-Rodas Juan Martín-Liberal Ainara Soria Pilar Lopez Criado Almudena Garcia-Castaño Aram Boada Pablo Ayala de Miguel Susana Puig Guillermo Crespo Alfonso Berrocal 《Journal of the American Academy of Dermatology》2021,84(5):1412-1415