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51.
Zalawadiya SK Veeranna V Panaich SS Afonso L Ghali JK 《The American journal of cardiology》2012,109(11):1664-1670
Limited information is available about gender and ethnic differences in red cell distribution width (RCDW) with regard to its relation to mortality in a population free of cardiovascular (CV) disease and diabetes. To assess gender and ethnic differences in RCDW and their effect on the association between RCDW and mortality, the Third National Health and Nutritional Examination Survey (n = 15,460, 1988 to 1994) data were examined. Multivariate adjusted Cox proportional hazard analysis was performed to assess effect of gender and ethnicity on the association between RCDW and mortality (total, CV disease, and coronary heart disease [CHD]). RCDW (mean ± SE) was greater in black women (13.1 ± 0.03) and men (13.4 ± 0.02) compared to women of white (12.9 ± 0.02) and other (13.0 ± 0.07) ethnicities and men of white (13.3 ± 0.02) and other (13.3 ± 0.07) ethnicities, respectively (p <0.001). The interaction between RCDW and gender was statistically significant for all study outcomes (p <0.001) but nonsignificant for RCDW and ethnicity. After adjusting for key variables, RCDW in women was associated with adjusted hazard ratios of 1.22 (95% confidence interval [CI] 1.14 to 1.31) for all-cause mortality, 1.17 (95% CI 1.07 to 1.28) for CV deaths, and 1.18 (95% CI 1.03 to 1.35) for CHD deaths; in men, adjusted hazard ratios were 1.29 (95% CI 1.20 to 1.38) for all-cause mortality, 1.27 (95% CI 1.17 to 1.37) for CV deaths, and 1.25 (95% CI 1.13 to 1.39) for CHD deaths (p <0.05 for all). In conclusion, blacks and men have significantly greater RCDWs compared to whites and women. Greater RCDW is associated with a greater risk of mortality in men compared to women, whereas no effect modification is observed by ethnicity. 相似文献
52.
Our understanding of the causes of periodontal disease have two major competing paradigms: one that focuses on ‘local’ etiologic factors and one that focuses on remote ‘host‐level’ factors. We provide a historical overview of local and remote cause hypotheses and discuss some key reasons why the local cause hypothesis has become dominant. 相似文献
53.
Marques DN da Mata AD Silveira JM Marques JR Amaral JP Guilherme NF 《Clinical oral investigations》2012,16(1):155-163
The objective of this study is to compare salivary hydrogen peroxide (HP) release kinetics and potential toxicity of systemic
exposure of four different whitening products. A double-blind, randomized controlled trial was conducted in a Portuguese dental
faculty clinic. Two hundred forty volunteers were randomized to eight intervention groups. Participants were randomly assigned
to receive active or placebo applications of one of four different products: Opalescence 10% PF™ (OPL), Vivastyle? 10%™ (VS10%),
Vivadent Paint On Plus™ (PO+), and Trés White Supreme™ (TWS). Saliva collection was obtained by established methods at different
times. The HP salivary content was determined by a photometric method. Salivary HP variations, total amount of salivary HP,
and counts of subjects above the safe daily HP dose were the main outcome measures. All whitening systems significantly released
HP to the saliva when compared to placebo, and all showed different release kinetics. The adaptable tray system (TWS) presented
a risk increase of 37% [20–54%, 95% confidence interval] when compared to the other systems. The use of an adaptable tray
whitening system with higher concentration of HP increases the toxicity potential. 相似文献
54.
Coelho-De-Souza FH Camargo JC Beskow T Balestrin MD Klein-Júnior CA Demarco FF 《Journal of applied oral science : revista FOB》2012,20(2):174-179
Objective
This randomized double-blind clinical trial compared the performance of posterior composite restorations with or without bevel, after 1-year follow-up.Material and Methods
Thirteen volunteers requiring at least two posterior composite restorations were selected. Twenty-nine cavities were performed, comprising 14 without bevel (butt joint) and 15 with bevel preparation of the enamel cavosurface angle. All cavities were restored with simplified adhesive system (Adper Single Bond) and composite resin (Filtek P60). A halogen light curing unit was used through the study. Restorations were polished immediately. Analysis was carried out at baseline, after 6 months and after 1 year by a calibrated evaluator (Kappa), according to the FDI criteria. Data were statistically analyzed by Mann-Whitney test (p<0.05).Results
Beveled and non-beveled cavities performed similarly after 1 year follow-up, regarding to fractures and retention, marginal adaptation, postoperative hypersensitivity, recurrence of caries, surface luster and anatomic form. However, for surface and marginal staining, beveled cavities showed significantly better performance (p<0.05) than butt joint restorations.Conclusions
It was concluded that the restorations were acceptable after 1 year, but restorations placed in cavities with marginal beveling showed less marginal staining than those placed in non-beveled cavities. 相似文献55.
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59.
Ryan T. Fitzgerald Joana Osorio Ashok Panigrahy George V. Mazariegos Giulio Zuccoli 《Pediatric neurology》2013,48(1):76-78
We report on tacrolimus-associated posterior reversible encephalopathy syndrome with the previously unreported finding of leptomeningeal enhancement occurring separate from the site of parenchymal magnetic resonance signal abnormality. Recognition of this atypical finding as a noninfectious cause of leptomeningeal enhancement may assist those caring for patients affected by posterior reversible encephalopathy syndrome. 相似文献
60.