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951.
Background
The efficacy of academic detailing in changing physicians' knowledge and practice has been the subject of many primary research publications and systematic reviews. However, there is little written about the features of academic detailing that physicians find valuable or that affect their use of it. The goal of our project was to explore family physicians' (FPs) perceptions of academic detailing and the factors that affect their use of it. 相似文献952.
Barbara Resnick Denise Orwig Janet Yu-Yahiro William Hawkes Michelle Shardell J. Richard Hebel Sheryl Zimmerman Justine Golden Michele Werner Jay Magaziner 《Annals of behavioral medicine》2007,34(1):67-76
Background: Exercise is an important strategy with potential to improve recovery in older adults following a hip fracture.Purpose: The purpose of this study was to test the impact of a self-efficacy based intervention, the Exercise Plus Program, and the
different components of the intervention, on self-efficacy, outcome expectations, and exercise behavior among older women
post-hip fracture.Methods: Participants were randomized to one of four groups: exercise plus, exercise only, plus only (i.e., motivation), or routine
care. Data collection was done at baseline (within 22 days of fracture), 2, 6, and 12 months post-hip fracture.Results: A total of 209 women were recruited with an average age of 81.0 years (SD=6.9). The majority was White (97.1%), was widowed
(57.2%), and had a high school education (66.7%). Generalized Estimating Equations were used to perform repeated measures
analyses. No differences in trajectories of recovery were observed for self-efficacy or outcome expectations. A statistically
significant difference in the overall trajectory of time in exercise was seen (p<.001), with more time spent exercising in
all three treatment groups.Conclusions: The study demonstrated that it was possible to engage these women in a home-based exercise program and that the plus only,
exercise only, and the exercise plus groups all increased exercise.
Support for this project was provided by National Institute on Aging grants R37 AG09901, R01-AG18668, R01 AG17082, and the
Claude D. Pepper Older Americans Independence Center P60-AG12583. 相似文献
953.
Timothy R. McAdams Karl R. Knudsen Naveen Yalamanchi James Chang Stuart B. Goodman 《Knee surgery, sports traumatology, arthroscopy》2007,15(9):1144-1149
The purpose of this study was to compare the histological characteristics of an autogenous fascia lata graft alone and a fascia
lata graft combined with a deltoid flap in the reconstruction of rotator cuff tears. Ten New Zealand white rabbits were divided
into two groups. Infraspinatus tendon defects (1 × 1 cm) were created in each animal. Reconstruction consisted of either a
fascia lata graft alone or a fascia lata graft combined with a distally based deltoid flap. At 3 months, tissue harvest and
histological analysis was performed. Compared to the fascia lata graft alone, there was significantly increased remodeling
activity and neovascularization in the group that included a deltoid flap. Also, there was pronounced interdigitation at the
graft/flap interface in the latter group. A mutually beneficial relationship may exist when an autogenous fascial graft is
combined with a functional deltoid flap for reconstructing large rotator cuff defects. 相似文献
954.
Eric Goodyer Frank Müller Katharina Licht Markus Hess 《European archives of oto-rhino-laryngology》2007,264(6):631-635
The shear modulus of the vocal fold is an essential parameter required to enhance our understanding of how the vocal fold
operates, to develop mathematical models of phonatation, and to provide benchmarks to quantify the effectiveness of surgical
procedures. The authors announced the successful deployment of an instrument to measure vocal fold elasticity in vivo last
year, and now present the data taken from eight patients in vivo. The shear modulus was measured at the mid-membranous point,
in a transverse direction with respect to the axis drawn between the anterior commissure and vocal process. The range of mean
shear modulus results is 701–2,225 Pa, with a mean value of 1,371 Pa. 相似文献
955.
Kyung Cheon Kim Kwang Jin Rhee Hyun Dae Shin Young Mo Kim 《Knee surgery, sports traumatology, arthroscopy》2007,15(12):1478-1481
Calcific tendinitis is a common condition with characteristic clinical and radiological findings. Although we do not know
which condition initiated the pathologic cascade, we present a rare case of calcific tendinitis of the long head of the biceps
brachii at its origin, associated with a SLAP lesion. The calcium deposit was removed and the SLAP lesion was repaired with
a suture anchor arthroscopically. 相似文献
956.
目的:观察兔骨髓基质细胞体外培养的生长行为及增殖、分化情况,探讨由骨髓分离培养神经干细胞的可行性和有效性。方法:无菌条件下行骨穿术,密度梯度离心分离获取骨髓基质细胞,利用多种增殖、分化诱导因子和神经干细胞培养液进行培养、分化诱导,用免疫细胞化学方法进行鉴定。结朵:骨髓基质细胞在体外培养中能形成NESTIN抗原阳性的细胞克隆团,进一步分化,部分细胞胞体增大并出芽,逐渐发育成为较成熟的长突起细胞,长突起相互连接、交织成网并建立纤维联系。结论:骨髓基质细胞具有较强的自我更新能力和多向分化潜能,易于取材、体外培养和增殖,在一定诱导条件下可以生成神经干细胞。 相似文献
957.
A linkage guide was devised for use in conjunction with knee arthroplasty instruments to achieve proper component rotation. The femoral component was rotationally aligned to the surgical epicondylar axis using one guide. The other guides were used after all bone surfaces were cut and soft tissue balancing was completed. A Kirschner wire was guided into the proximal tibial aspect parallel to the sagittal plane of the femoral component with the patella in its normal position and the knee in full extension. The wire was used as a reference to determine tibial component rotation. The relative rotational alignment of 21 knees in 19 patients who had undergone cruciate-retaining total knee arthroplasty utilizing this guide was assessed using the modified Eckhoff method. The results of radiographic analysis were compared with those in a control group of 25 knees where the guide was not employed. The external rotation of the femoral component relative to the tibial component was 1.3° ± 2.0° (mean ± SD) in the guided group and 1.1° ± 4.4° in the control group. The relative rotational angle was significantly more consistent using the guide. Implant malrotation can be reduced using our technique. 相似文献
958.
男性不育患者精浆尿酸的检测及临床意义初探 总被引:4,自引:1,他引:3
目的 :检测男性不育患者精浆尿酸的含量 ,并探讨其与不育的关系。 方法 :2 0 0 3年 2~ 8月就诊的男性不育患者 1 6 3例 ,分为 4组 :梗阻性无精子症组 ,1 5例 ;非梗阻性无精子症组 ,36例 ;少精子症组 ,4 3例 ;弱精子症组 ,6 9例。 2 0例正常生育男性为正常对照组。上述各组均作精液参数分析及精浆尿酸含量的测定。 结果 :正常对照组精浆尿酸含量为 (396 .9± 5 3.1 ) μmol/L ,显著高于梗阻性无精子症组 [(79.5± 1 8.1 ) μmol/L]、非梗阻性无精子症组[(2 4 5 .8± 76 .5 ) μmol/L]、少精子症组 [(2 6 2 .2± 79.2 ) μmol/L]和弱精子症组 [(2 5 1 .4± 75 .4 ) μmol/L](P均 <0 .0 1 )。其中 ,梗阻性无精子症组精浆尿酸含量又显著低于其他各不育症组 (P均 <0 .0 1 ) ,其余各不育症组间精浆尿酸含量差异无显著性 (P >0 .0 5 )。 结论 :精浆中尿酸作为生殖系统中的一种重要抗氧化物 ,可能在男性生殖中具有一定意义。 相似文献
959.
阿合奇县柯尔克孜族女学生月经初潮状况的调查分析 总被引:1,自引:0,他引:1
目的:对阿合奇县柯尔克孜族女学生月经初潮年龄、身高、体重、痛经状况及经前症状等进行现况调查,为研究新疆柯尔克孜族人群的发育水平提供参考资料。方法:问卷形式进行调查,采用寿命表法计算初潮年龄等并采用作图法显示整个月经来潮过程。结果:柯尔克孜族女学生月经初潮年龄高峰为14岁,初潮发生季节高峰为夏季,平均初潮年龄呈提前趋势,有痛经和经前症状者较多。月经初潮对身高、体重有一定影响。结论:阿合奇县柯尔克孜族女学生平均初潮年龄明显提前,与我国汉族和其他少数民族青少年生长发育特点一致。 相似文献
960.
Dendritic Cells Coinjected with Tumor Cells Treated with an Anticancer Drug to Induce Tumor Rejection 总被引:1,自引:0,他引:1
Naoya Inoue Seiji Yamasaki Kan Kondo Takatsugu Kan Katsuyoshi Furumoto Masayuki Imamura 《Surgery today》2003,33(4):269-276
Purpose: We examined whether bone marrow-derived dendritic cells (DCs) could induce antitumor immunity when a chemotherapeutic drug
was added.
Methods: CT26 (a murine colon cancer cell line syngeneic with BALB/c) and CT26-bearing mice were treated with mitomycin C (MMC) intraperitoneally
(i.p.). Next, mice immunized with a coinjection of DCs and MMC-treated CT26 (i.p.) were given an intradermal inoculation of
CT26. Finally, CT26-bearing mice were treated with MMC (i.p.) with or without DCs, given peritumorally.
Results: Although the inoculated tumor was not rejected in the control mice, CT26 was rejected in 50% of the mice injected with MMC
alone. Apoptosis was observed in the MMC-treated CT26 cells in vitro and in vivo. Immunization with DCs and apoptotic CT26
cells, but not with apoptotic CT26 alone, gave protection against tumor challenge in 7 of 13 mice. A significantly higher
level of cytotoxic T-cell activity and interferon-γ production was seen in the protected mice. When MMC (i.p.) treatment was
followed by peritumoral DC injection in the CT26-bearing mice, remarkable therapeutic effects were observed.
Conclusion: DCs can collaborate with chemotherapy-induced apoptotic tumor cells and elicit improved antitumor immunity, probably through
the acquisition of tumor-associated antigens from apoptotic tumor cells.
Received: January 7, 2002 / Accepted: September 3, 2002
Acknowledgments. We thank Dr. Kazuo Kinoshita for his useful advice on using flow cytometry. This research was partly supported by the Ministry
of Education, Culture, Sports, Science and Technology (No. 11671160).
Reprint requests to: S. Yamasaki 相似文献