The effects of autologous platelet gel on wound healing

Laser resurfacing techniques have become a popular means of achieving rejuvenation of damaged skin. Interest is great in attempting to speed re-epithelialization and healing so that patients can return to their normal activities as quickly as possible. Previous studies have demonstrated that wounds heal more quickly when they are covered and kept moist than when they are left open to the air. Until now, no study has been conducted to investigate whether the healing process of a superficial skin burn might be accelerated by the use of an autologous platelet gel as a biologic dressing. Our study of five pigs showed that autologous platelet gel can influence wound healing by stimulating an intense inflammatory process that leads to highly significant increases in the production of extracellular matrices and granulation tissue. The platelet gel accelerated vascular ingrowth, increased fibroblastic proliferation, and accelerated collagen production. However, the gel did not appear to accelerate re-epithelialization. The aggressive production of granulation tissue and the acceleration of collagen production might mean that autologous platelet gel will have a future role in the treatment of burns because the highly vascularized bed it helps create should promote the success of skin grafting in patients with deep partial-thickness and full-thickness burns.     

Shiga toxin-producing Escherichia coli

Shiga toxin-producing Escherichia coli (STEC) are emerging as a significant source of foodborne infectious disease in the developed world. Multistate outbreaks of E. coli O157 and non-O157 serogroups in the United States are facilitated by the centralization of food processing and distribution. Our ability to recognize the clonality of these clusters has been advanced by developments in molecular detection techniques and in the establishment of active surveillance practices. These studies have helped identify important risk factors for both sporadic and outbreak STEC infection, allowing us to develop appropriate prevention strategies. Identification of these factors is of critical importance because of the lack of adequate treatments available. This brief review of the literature discusses major developments in the epidemiology, pathogenesis, diagnosis, treatment, and prevention of STEC disease published in the past few years.     

Cluster Models in Cellular Level Electron Dose Calculations

A program for calculating absorbed dose was developed for radioimmunotherapy (RIT) purposes. It was used to determine the difference in the therapeutic effect of ¹¹¹     

When Snitches Corroborate: Effects of Post-identification Feedback from a Potentially Compromised Source

Feedback provided to eyewitnesses can influence memory as to how confident their previous line-up selections were. Witnesses given confirming feedback remember being more confident than witnesses who are told their selection was incorrect regardless of their accuracy. This can have a powerful impact on judges and juries. In this article, we examine the effect of feedback from a ‘snitch’ (a jailhouse informant). This manipulation often occurs in real cases, despite that fact that snitches could have something to gain from providing information to police. Our participants witnessed a staged crime and then identified the perpetrator from a target-absent line-up. Two days later, participants were provided with feedback and were probed for confidence. Results show that confirming feedback from a snitch has the same effect as a confession made by the actual suspect, and disconfirming feedback reduces confidence. Implications and relation to the extant literature on eyewitness confidence are discussed.     

Benefit of social media on patient engagement and satisfaction: Results of a 9-month,qualitative pilot study using Facebook

Background

Despite the potential benefits of social media, health care providers are often hesitant to engage patients through these sites. Our aim was to explore how implementation of social media may affect patient engagement and satisfaction.