全文获取类型
收费全文 | 1476篇 |
免费 | 80篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 28篇 |
妇产科学 | 44篇 |
基础医学 | 158篇 |
口腔科学 | 17篇 |
临床医学 | 99篇 |
内科学 | 513篇 |
皮肤病学 | 6篇 |
神经病学 | 157篇 |
特种医学 | 58篇 |
外科学 | 164篇 |
综合类 | 3篇 |
一般理论 | 2篇 |
预防医学 | 110篇 |
眼科学 | 31篇 |
药学 | 48篇 |
中国医学 | 6篇 |
肿瘤学 | 121篇 |
出版年
2024年 | 2篇 |
2023年 | 15篇 |
2022年 | 23篇 |
2021年 | 50篇 |
2020年 | 24篇 |
2019年 | 36篇 |
2018年 | 45篇 |
2017年 | 39篇 |
2016年 | 25篇 |
2015年 | 34篇 |
2014年 | 69篇 |
2013年 | 75篇 |
2012年 | 132篇 |
2011年 | 158篇 |
2010年 | 81篇 |
2009年 | 65篇 |
2008年 | 110篇 |
2007年 | 100篇 |
2006年 | 93篇 |
2005年 | 68篇 |
2004年 | 91篇 |
2003年 | 81篇 |
2002年 | 69篇 |
2001年 | 8篇 |
2000年 | 8篇 |
1999年 | 10篇 |
1998年 | 17篇 |
1997年 | 5篇 |
1996年 | 8篇 |
1995年 | 5篇 |
1994年 | 6篇 |
1993年 | 6篇 |
1992年 | 1篇 |
1991年 | 4篇 |
1990年 | 1篇 |
1989年 | 3篇 |
1988年 | 1篇 |
1987年 | 1篇 |
1981年 | 1篇 |
排序方式: 共有1570条查询结果,搜索用时 15 毫秒
131.
132.
133.
134.
135.
136.
137.
Manfredonia F Ciccarelli O Khaleeli Z Tozer DJ Sastre-Garriga J Miller DH Thompson AJ 《Archives of neurology》2007,64(3):411-415
OBJECTIVE: To investigate whether patients with early primary progressive multiple sclerosis show changes in T1 relaxation time (T1-RT) in normal-appearing white matter (NAWM) and normal-appearing gray matter (NAGM) during 2 years and whether T1-RT at baseline predicts disability. METHODS: Twenty-one patients and 12 control subjects were studied at baseline and after 2 years. Expanded Disability Status Scale (EDSS) and Multiple Sclerosis Functional Composite (MSFC) scores were assessed. T1 relaxation time histograms of NAWM and NAGM were obtained in all subjects, and mean, peak height, and peak location of the histograms were measured. Paired t tests were used to compare baseline and 2-year histogram values in patients and control subjects. To investigate whether T1-RT predicted clinical changes, multiple linear regression analysis was used. RESULTS: Patients showed increases in NAWM and NAGM T1-RT mean and peak location during follow-up, and significant decreases in NAWM and NAGM peak height. Baseline NAWM T1-RT mean values and peak height predicted disability at 2 years, as measured with the Multiple Sclerosis Functional Composite score. CONCLUSION: T1 relaxometry is a good marker of disease progression and has prognostic potential in primary progressive multiple sclerosis. 相似文献
138.
Application of fibrin glue sealant after hepatectomy does not seem justified: results of a randomized study in 300 patients 总被引:3,自引:0,他引:3
下载免费PDF全文
![点击此处可从《Annals of surgery》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Figueras J Llado L Miro M Ramos E Torras J Fabregat J Serrano T 《Annals of surgery》2007,245(4):536-542
OBJECTIVE: To evaluate the efficacy, amount of hemorrhage, biliary leakage, complications, and postoperative evolution after fibrin glue sealant application in patients undergoing liver resection. SUMMARY BACKGROUND DATA: Fibrin sealants have become popular as a means of improving perioperative hemostasis and reducing biliary leakage after liver surgery. However, trials regarding its use in liver surgery remain limited and of poor methodologic quality. PATIENTS AND METHODS: A total of 300 patients undergoing hepatic resection were randomly assigned to fibrin glue application or control groups. Characteristics and debit of drainage and postoperative complications were evaluated. The amount of blood loss, measurements of hematologic parameters liver test, and postoperative evolution (particularly involving biliary fistula and morbidity) was also recorded. RESULTS: Postoperatively, no differences were observed in the amount of transfusion (0.15 +/- 0.66 vs. 0.17 +/- 0.63 PRCU; P = 0.7234) or in the patients that required transfusion (18% vs. 12%; P = 0.2), respectively, for the fibrin glue or control group. There were no differences in overall drainage volumes (1180 +/- 2528 vs. 960 +/- 1253 mL) or in days of postoperative drainage (7.9 +/- 5 vs. 7.1 +/- 4.7). Incidence of biliary fistula was similar in the fibrin glue and control groups, (10% vs. 11%). There were no differences regarding postoperative morbidity between groups (23% vs. 23%; P = 1). CONCLUSIONS: Application of fibrin sealant in the raw surface of the liver does not seem justified. Blood loss, transfusion, incidence of biliary fistula, and outcome are comparable to patients without fibrin glue. Therefore, discontinuation of routine use of fibrin sealant would result in significant cost saving. 相似文献
139.
Extrahepatic complications from hepatic cystic echinococcosis are rare and may be life threatening. Although the prevalence of echinococcosis in Spain had decreased, the number of cases of this disease and its severity has risen again due to immigration. We report the case of a patient with a giant hepatic echinococcus cyst diagnosed during investigation of an abdominal mass. The mass was associated with three other cysts: the first cyst was fistulized to the biliary tract, without clinical or laboratory alterations, the second cyst was fistulized to the right pleural cavity, leading to pleural echinococcosis and respiratory distress due to massive pleural effusion, and the third cyst was calcified. The challenge in this case layed in its diagnosis and treatment. The clinical presentation was unusual due to the extension of the disease, hampering complete cystic excision. 相似文献
140.