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排序方式: 共有10000条查询结果,搜索用时 31 毫秒
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A. Bersano L. Candelise R. Sterzi G. Micieli M. Gattinoni A. Morabito 《Neurological sciences》2006,27(5):332-339
Abstract The future challenge for improving stroke patients’ outcome will be to implement new Stroke Units (SUs) worldwide. However
the best SU model remains uncertain. The aim of this study was to evaluate the number of SUs and the quality characteristics
of acute stroke care in Italy. We conducted a SU survey in Italy, interviewing the directors of the hospital wards that discharged
at least 50 acute stroke patients a year. A SU was defined as an acute ward area with stroke-dedicated beds and staff. To
compare the quality of care provided in SUs with that in general wards (GWs) we investigated the characteristics of five domains:
hospital setting, unit setting, staffing, process of care and diagnostic investigations. We identified 68 SUs and 677 GWs.
Multivariate logistic regression analyses demonstrated that SUs compared to GWs had higher quality scores in unit setting
(ROC area=0.9721), staffing (ROC area=0.8760) and care organisation (ROC area=0.7984). The hospital setting (ROC area=0.7033)
and the availability of rapid diagnostic investigations (ROC area=0.7164) had lower power in discriminating SU from GW. In
Italy in 2003/04 only 9% of the hospital services had organised SU care. The study demonstrated that SUs admitted more than
100 patients per year, had more monitoring equipment and staffing time, and practised multidisciplinary meetings and early
mobilisation. The utility of these structural and performance characteristics needs validation from outcome studies. 相似文献
953.
Gregory Guldner MD MS Jason Schultz BS Perry Sexton MD Corwyn Fortner BS Mark Richmond MD 《Academic emergency medicine》2003,10(2):134-139
OBJECTIVES: Physicians commonly use etomidate for adult rapid-sequence intubation (RSI), but the manufacturer does not recommend its use for children under 10 years of age due to a lack of data. The authors present their experience with etomidate for pediatric RSI in order to further develop its risk-benefit profile in this age group. METHODS: Trained abstractors reviewed the medical records for all children under 10 years old who received etomidate for RSI between July 1996 and April 2001. RESULTS: 105 children, with an average age of 3 (+/-2.9) years, received a median dose of 0.32 (+/-0.12) mg/kg of etomidate. The systolic blood pressure increased an average of 4 mm Hg (95% CI = -3.3 to 9.2); the diastolic blood pressure increased 7 mm Hg (95% CI = -3.1 to 11) within 10 minutes of receiving etomidate. The heart rate increased an average of 10 beats/min (95% CI = 4.0 to 17.4). Complications included three patients who vomited within 10 minutes of etomidate administration. There were no cases of documented myoclonus, status epilepticus, or new-onset seizures. Thirty-eight patients received corticosteroids during the hospital course, none for suspected adrenal insufficiency. Three patients died, all from severe brain injury. CONCLUSIONS: In children less than 10 years old, etomidate seems to produce minimal hemodynamic changes, and appears to have a low risk of clinically important adrenal insufficiency, myoclonus, and status epilepticus. The association between etomidate and emesis (observed in less than 3% of enrolled patients) remains unclear. For clinical situations in which minimal blood pressure changes during RSI are critical, etomidate appears to have a favorable risk-benefit profile for children under 10 years old. 相似文献
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Claire M Rickard Brigit L Roberts Jonathon Foote Matthew R McGrail 《Dimensions of critical care nursing》2006,25(5):234-242
Research coordinators in intensive care are a growing specialty about which little is known. This cross-sectional study surveyed the Australia and New Zealand Intensive Care Research Coordinators' Group (n = 49) regarding demographics, education, employment history, job structure, and role content. Most research coordinators were highly qualified and experienced nurses who undertake pharmaceutical trials, multicenter projects, departmental medical and nursing research, audits and data registries, and their own projects. 相似文献
956.
Robin L. Bissinger MSN RNC NNP Cheryl A. Carlson MS RNC NNP 《Newborn and Infant Nursing Reviews》2006,6(2):87
Surfactant, a complex substance containing specific proteins and phospholipids, is essential for gas exchange in the lungs. Research shows that surfactant not only lowers surface tension, but also plays a role in host defense. Surfactant replacement therapy is a cornerstone in the treatment of respiratory distress syndrome in premature infants. New information on endogenous surfactant composition including surfactant apoproteins has led to advances in the surfactant replacement products currently available. Because of the success of surfactant deficiency treatment in neonates, surfactant replacement therapy has been studied in both the pediatric and adult population for the treatment of other respiratory disorders. This article describes the composition, metabolism, and function of endogenous surfactant and other uses of surfactant replacement therapies in neonates. 相似文献
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