全文获取类型
收费全文 | 83425篇 |
免费 | 5311篇 |
国内免费 | 846篇 |
专业分类
耳鼻咽喉 | 1572篇 |
儿科学 | 1008篇 |
妇产科学 | 1254篇 |
基础医学 | 14100篇 |
口腔科学 | 2195篇 |
临床医学 | 7456篇 |
内科学 | 15337篇 |
皮肤病学 | 2924篇 |
神经病学 | 6207篇 |
特种医学 | 4837篇 |
外科学 | 11018篇 |
综合类 | 358篇 |
现状与发展 | 3篇 |
一般理论 | 30篇 |
预防医学 | 3806篇 |
眼科学 | 1829篇 |
药学 | 7767篇 |
中国医学 | 1046篇 |
肿瘤学 | 6835篇 |
出版年
2023年 | 627篇 |
2022年 | 2014篇 |
2021年 | 3125篇 |
2020年 | 1553篇 |
2019年 | 2039篇 |
2018年 | 2560篇 |
2017年 | 2004篇 |
2016年 | 2887篇 |
2015年 | 3978篇 |
2014年 | 4562篇 |
2013年 | 5288篇 |
2012年 | 7872篇 |
2011年 | 7274篇 |
2010年 | 4239篇 |
2009年 | 3508篇 |
2008年 | 5032篇 |
2007年 | 4530篇 |
2006年 | 3899篇 |
2005年 | 3557篇 |
2004年 | 2944篇 |
2003年 | 2532篇 |
2002年 | 2167篇 |
2001年 | 1754篇 |
2000年 | 1610篇 |
1999年 | 1204篇 |
1998年 | 513篇 |
1997年 | 379篇 |
1996年 | 299篇 |
1995年 | 250篇 |
1994年 | 234篇 |
1993年 | 206篇 |
1992年 | 441篇 |
1991年 | 456篇 |
1990年 | 395篇 |
1989年 | 363篇 |
1988年 | 345篇 |
1987年 | 327篇 |
1986年 | 260篇 |
1985年 | 227篇 |
1984年 | 172篇 |
1983年 | 149篇 |
1982年 | 85篇 |
1981年 | 88篇 |
1979年 | 136篇 |
1978年 | 107篇 |
1975年 | 102篇 |
1974年 | 92篇 |
1972年 | 92篇 |
1971年 | 87篇 |
1970年 | 83篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
31.
32.
Clinical clues for differential diagnosis between verruca plana and verruca plana‐like seborrheic keratosis 下载免费PDF全文
Won‐Jeong Kim Won‐Ku Lee Margaret Song Hoon‐Soo Kim Hyun‐Chang Ko Byung‐Soo Kim Moon‐Bum Kim 《The Journal of dermatology》2015,42(4):373-377
Sometimes the clinical differentiation between verruca plana (VP) and VP‐like seborrheic keratosis (SK) could be challenged. However, there have been no studies on this issue to date. The aim of this study was to elucidate clinical and dermoscopic differences between these two diseases, and also to suggest a diagnostic algorithm of VP and VP‐like SK without skin biopsy. The patients who had lesions clinically considered as VP or VP‐like SK were the target of our study. We took clinical and dermoscopic photos with informed consent and conducted a questionnaire. All patients had their diagnoses confirmed by biopsy. Thirty‐three patients were enrolled in our study. Seventeen patients were finally diagnosed with VP (51.5%) and 16 patients with VP‐like SK (48.5%). In clinical findings, VP‐like SK showed significantly more scattered distribution than VP (P = 0.039), which exhibited more clustered or grouped distribution (P = 0.039). In dermoscopic findings, brain‐like appearance was more commonly observed in VP‐like SK (P = 0.003) whereas VP showed more red dots or globular vessels (P = 0.017) and even‐colored light brown to yellow patch (P < 0.001). Sex, onset age, the size of each lesion, location, color and shape showed no significant differences between them (P > 0.05). Based on our results, we suggest a diagnostic algorithm using Koebner's phenomenon, dermoscopic findings, distribution of each lesion and biopsy for multiple VP‐like lesions in adults, and we think it will be a very useful diagnostic tool in daily clinical dermatological practice. 相似文献
33.
Clinical usefulness of intraductal ultrasonography for the management of acute biliary pancreatitis 下载免费PDF全文
34.
Fluid is usually restricted during thoracic surgery, and vasoactive agents are often administered to maintain blood pressure. One-lung ventilation (OLV) decreases arterial oxygenation; thus oxygen delivery to the brain can be decreased. In this study, we compared phenylephrine and dopamine with respect to maintaining cerebral oxygenation during OLV in major thoracic surgery.Sixty-three patients undergoing lobectomies were randomly assigned to the dopamine (D) or phenylephrine (P) group. The patients’ mean arterial pressure was maintained within 20% of baseline by a continuous infusion of dopamine or phenylephrine. Maintenance fluid was kept at 5 mL/kg/h. The depth of anesthesia was maintained with desflurane 1MAC and remifentanil infusion under bispectral index guidance. Regional cerebral oxygen saturation (rScO2) and hemodynamic variables were recorded using near-infrared spectroscopy and esophageal cardiac Doppler.The rScO2 was higher in the D group than the P group during OLV (OLV 60 min: 71 ± 6% vs 63 ± 12%; P = 0.03). The number of patients whose rScO2 dropped more than 20% from baseline was 0 and 6 in the D and P groups, respectively (P = 0.02). The D group showed higher cardiac output, but lower mean arterial pressure than the P group (4.7 ± 1.0 vs 3.9 ± 1.2 L/min; 76.7 ± 8.1 vs 84.5 ± 7.5 mm Hg; P = 0.02, P = 0.02). Among the variables, age, hemoglobin concentration, and cardiac output were associated with rScO2 by correlation analysis.Dopamine was superior to phenylephrine in maintaining cerebral oxygenation during OLV in thoracic surgery. 相似文献
35.
36.
37.
Recent studies have reported an association between gastroesophageal reflux disease (GERD) and atrial fibrillation (AF). The objective of the present study was to evaluate whether AF is one of the risk factors for GERD occurrence.In this hospital-based, retrospective, case–control study, the patients were classified into 2 groups. The patients diagnosed with new AF were assigned to the AF group (n = 1612); those diagnosed without AF and GERD were assigned to the control group (n = 1612). The subjects in the control group were selected from outpatients of total healthcare center without a history of AF or GERD, and matched for age and gender. We evaluated the incidence of GERD and risk factors for GERD occurrence between the 2 groups.The number of patients experiencing occurrence of GERD during the follow-up period was significantly higher in the AF group than those in the control group, respectively (129 patients vs 98 subjects, P = 0.037). The incidence of GERD was significantly higher in the AF group than in the control group by Kaplan–Meier analysis with log-rank test (P = 0.008). The AF group''s adjusted hazard ratio of GERD occurrence against that of the control group was 1.37 (95% confidence interval [CI]: 1.16–1.57; P = 0.009) according to Cox''s proportional hazard model.The presence of AF appears to increase the incidence of GERD and may be considered a risk factor for the development of GERD. Further, large prospective and cohort studies will be required to better establish the correlation of GERD with AF. 相似文献
38.
Lee Mi Jung Romero Sergio Velozo Craig A. Gruber-Baldini Ann L. Shulman Lisa M. 《Quality of life research》2019,28(6):1595-1603
Quality of Life Research - This study investigated the PROMIS Self-Efficacy Measure for Managing Chronic Conditions (PROMIS-SE) domain distributions and examined the factor structure of the... 相似文献
39.
Interaction effects between the 5‐hydroxy tryptamine transporter‐linked polymorphic region (5‐HTTLPR) genotype and family conflict on adolescent alcohol use and misuse 下载免费PDF全文