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981.
Dal Pizzol Tda S Pons Eda S Hugo FN Bozzetti MC Sousa Mda L Hilgert JB 《Cadernos de saúde pública / Ministério da Saúde, Funda??o Oswaldo Cruz, Escola Nacional de Saúde Pública》2012,28(1):104-114
The study aimed to measure use of medication and polypharmacy among the elderly in Carlos Barbosa, Rio Grande do Sul State, Brazil, and to compare socio-demographic, economic, and health characteristics in relation to area of residence (urban versus rural) in a random sample of 811 persons 60 year of age or older. Interviews were used to collect data on socio-demographic characteristics, chronic illnesses, and self-reported use of medications. The association between area of residence and medication or polypharmacy was adjusted for confounders using Poisson regression with robust variance. Prevalence rates for use of medication and polypharmacy were higher among older persons living in the urban area. Living in the urban area was positively and independently associated with use of medication (PR = 1.10; 95%CI: 1.02-1.20) and polypharmacy (PR = 1.83; 95%CI: 1.27-2.65) in this group of elderly in southern Brazil. 相似文献
982.
Marc Derieppe Baudouin Denis de Senneville Hugo Kuijf Chrit Moonen Clemens Bos 《Molecular imaging and biology》2014,16(5):642-651
Purpose
Previously, we demonstrated the feasibility to monitor ultrasound-mediated uptake of a cell-impermeable model drug in real time with fibered confocal fluorescence microscopy. Here, we present a complete post-processing methodology, which corrects for cell displacements, to improve the accuracy of pharmacokinetic parameter estimation.Procedures
Nucleus detection was performed based on the radial symmetry transform algorithm. Cell tracking used an iterative closest point approach. Pharmacokinetic parameters were calculated by fitting a two-compartment model to the time-intensity curves of individual cells.Results
Cells were tracked successfully, improving time-intensity curve accuracy and pharmacokinetic parameter estimation. With tracking, 93 % of the 370 nuclei showed a fluorescence signal variation that was well-described by a two-compartment model. In addition, parameter distributions were narrower, thus increasing precision.Conclusions
Dedicated image analysis was implemented and enabled studying ultrasound-mediated model drug uptake kinetics in hundreds of cells per experiment, using fiber-based confocal fluorescence microscopy. 相似文献983.
António Miguel Ferreira Hugo Café Katya Reis Santos Júlia Toste Hugo Marques 《The international journal of cardiovascular imaging》2014,30(4):783-784
We report the incidental finding of a muscular congenital diverticulum of the left ventricular apex in a young adult with AV node reentry tachycardia. The role of cardiovascular magnetic resonance in the differential diagnosis of this rare cardiac malformation is briefly discussed. 相似文献
984.
Vitor Hugo Pereira João Português Lucy Calvo Inocência Machado Olga Azevedo António Lourenço 《The international journal of cardiovascular imaging》2014,30(6):1203-1204
The image shows a pseudoaneurysm of the mitral-aortic intervalvular fibrosa and a fistula between the non-coronary sinus and the left atrium. 相似文献
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A 71-year-old woman, undergoing coronary angiography during preoperative evaluation for a major noncardiac surgery, was fortuitously detected as having penetrating atherosclerotic ulcer of the ascending aorta 5 years after coronary artery bypass surgery. While acute aortic dissections have been described after coronary bypass grafting, penetrating atherosclerotic ulcer of the ascending aorta as a delayed complication of bypass surgery has never been reported. The patient was treated conservatively and closely observed. A brief review of literature is also presented. 相似文献
988.
Prosthetic Survival and Complication Rate of Single Implant Treatment in the Periodontally Healthy Patient after 16 to 22 Years of Follow‐Up 下载免费PDF全文
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